All issues
Volume 78, Issue 11
Displaying 1-7 of 7 articles from this issue
- |<
- <
- 1
- >
- >|
-
HISTOPATHOLOGICAL FINDINGS OF THE INTERNAL BRANCH OF THE SUPERIOR LARYNGEAL NERVE AFTER REGENERATIONISEI SATOH1975 Volume 78 Issue 11 Pages 1141-1143
Published: November 20, 1975
Released on J-STAGE: March 19, 2008
JOURNAL FREE ACCESSRegeneration of, the internal branch of the superior laryngeal nerve was studied after the nerve was sectioned and immediately sutured. The nerve was sectioned and sutured lilaterally in five dogs in this experiment. Ten months after operation, longitudinal sections of the nerve including portion of the nerve suture and cross sections of the nerve 1em peripheral and central to the suture were prepared and stained by using the phosphotungstic acid hematoxylin method. Mucous membranes of the posterior wall of the larynx were also sectioned and stained by silver.
As the results, each regenerative nerve formed a neuroma at the portion of the nerve sutured. In the nerve peripheral so the suture, remarkable proliferation of connective tissue surrounding each axon was recognized and decrease of the diameter of axons was observed. In the nerve central to the suture, only proliferation of connective tissue surrounding axon was observed. Moreover, the nerve ending fibers were observed in mucous membrane of the posterior wall of the larynx although these fibers seemed decreased in their number.
These results lead us to the conclusion that the internal branch of the superior laryngeal nerve does not recover perfectly after this nerve was sectioned and then repaired immediately.View full abstractDownload PDF (997K) -
KOUJI OKUZAWA1975 Volume 78 Issue 11 Pages 1144-1153
Published: November 20, 1975
Released on J-STAGE: March 19, 2008
JOURNAL FREE ACCESSP-K (Prausnitz-Kustner) reaction tests have conventionally been used for proof of reaginic antibodies in vivo in immediate type nasal allergosis. Recently, however, Ishizaka et al.discovered IgE, a carrier of reagin, and Krotzer et al., and Honda et al. made it possible to prove the reaginic antibody in vitro by applying rat mast cell degranulation in allergen-reaginic antibody reactions.
As screening of patients with nasal allergosis, measurement of serum IgE levels and an improved type of rat mast cell degranulation test were performed as well as conventional in vivo tests. The results were as follows;
1. In immediate type nasal allergy (Japanese cedar pollinosis and house dust hypersensitivity) the results of the provocation tests and intracutaneous skin tests showed a correlation with the results of the RMCD (Rat Mast Cell Degranulation) method and the appearance rate of eosinophile in nasal secretion.
2. Among Patients tested those having the serum IgE value of 700 ng/ml or more showed positive in the RMCD test, while 80-86% of the patients with the serum IgE value of less than 700 ng/ml also showed positive in the RMCD test.
3. It has been proved that the RMCD method is effective in screening of various sensitized antigens and that this method can be a substitute for the conventional P-K reaction test.View full abstractDownload PDF (1365K) -
YASUO SAKAKURA, YASURO MIYOSHI, KOTARO UKAI, YUICHI MAJIMA, SEIICHIRO ...1975 Volume 78 Issue 11 Pages 1154-1161
Published: November 20, 1975
Released on J-STAGE: March 19, 2008
JOURNAL FREE ACCESSSalivary IgA levels in healthy adults and children and in otolaryngological patients were measured by electroimmunodiffusion based on the hypothesis that secretory IgA might have an important role in chronic infection of the middle ear, maxillary sinus and palatine tonsil. Salivary IgA levels were as follow: normal adults, 3.2mg/d1±1.92 (N=57); normal children, 2.8mg/d1±2.37 (N=93); adults with chronic otitis media, 2.Omg/dl±1.21 (N=39); adults with chronic sinusitis, 1.6mg/d1±1.08mg/dl± (N=27) and children with chronic tonsilitis, 1.0mg/dl ±0.86 (N=32). The differences in mean salivary IgA concentration between the control and the patients with chronic otitis media, chronic sinusitis and chronic tonsillitis were highly significant at the level of P<0.005. This suggests that local IgA production decreases in these patients. Measu rements of a concentration of salivary IgA may be useful as an indicator of local IgA production in otolaryngic patients. In the next study, the volunteers were exposed to cold outdoor climate for two hours and then were asked to eat very hot noodles. The first gush of excess nasal secretion was collected for secretory IgA determination. The mean IgA level was 14.9mg/dl±8.44 in normal nasal secretion and 145.3mg/dl±157.4 in maxillary secretion from chronic sinusitis. The bulk of maxillary IgA might be derived from serum. A concentration of IgA and secretory piece was compared between saliva and nasal secretion from the same individual in normal subjects, and saliva and maxillary secretion from the patients with chronic sinusitis respectively. A ratio of salivary IgA to nasal averaged 11.0, while a ratio in secetory piece averaged 2.5. There was no relationship to a concentration of IgA betweensaliva and nasal secretion. A ratio of salivary IgA to maxillary averaged 237, while a ratio in secretory piece averaged 1.4. It should be mentioned that secretory piece was not detected in 5 of 14 maxillary secretions. Such deficiency might be due to a failure of production of secretory piece of the.infected epithelial cells.View full abstractDownload PDF (585K) -
NOBUO USUI1975 Volume 78 Issue 11 Pages 1162-1168
Published: November 20, 1975
Released on J-STAGE: March 19, 2008
JOURNAL FREE ACCESSThe respiratory effect of mild irritants to the nasal mucous membrane has been studied by a number of researchers.
Some investigators have reported an increase in pulmonary resistance; Others have noted a decrease. This study was undertaken to learn whether stimulation to the receptors site in the nose can initiate an increase or decrease in tracheobronchial airflow resistance in man.
The experiments were made on 12 laryngectomized patients ranging in age from 50 to 77 years.
The measurements before and after irritation of the nasal mucosa were obtained as follows:
1) during normal breathing,
2) after swab stick stimulation for right nose,
3) after swab stick stimulation for left nose. In addition, all subjects received 0. 5mg atropine sulfate subcutaneously, and 25 minutes later the same measurements were performed before and after nasal stimulation.
Lower pulmonary resistance decreased after irritation of the nasal mucosa. Injection of atropine caused greater decrease of lower pulmonary resistance after nasal stimulation. This decrease in pulmonary resistance suggests that bronchial dilatation occurred.
Our study demonstrated that a reflex arc existed between the nose and the lungs in laryngec. tomized patients.View full abstractDownload PDF (1184K) -
AKIYOSHI KONNO, KIYOSHI TOGAWA, KOICHIRO HIGASHI, SUSUMU UCHIKOSHI, TA ...1975 Volume 78 Issue 11 Pages 1169-1176
Published: November 20, 1975
Released on J-STAGE: March 19, 2008
JOURNAL FREE ACCESSFourty cases of maxillary carcinoma, treated by combined therapy of irradiation, intra-arterial infusion of 5-FU and aspiration of necrotized mass through the control window in the gingivobuccal fold, in Akita University Hospital in a three years period between 1971 and 1974, were investigated clinically and histopathologically. Fourteen cases of squamous cell carcinoma, treated by the combined therapy and surgery and followed up for a period of 1-3years, were all alive without recurrence or metastasis. Incidence of cervical lymph node and distant metastsis was closely related to histological typeof the tumor, and highly frequent distant metastasis was found in anaplastic carcinoma. Twenty-eight surgical specimens obtained by partial, total or extended total maxillectomy after combined therapy were examined microscopically to evaluate histological effectiveness of the combined therapy and its relationship to histological type and staging of the tumor. Evidence of high correlation between them might help us in selecting the mode of treatment, conservative or radical operation, in individual cases. Histological classification used in this study was as follows: 1) Squamous cell carcinoma well differentiated type (9 cases) moderately differentiated type (3 cases) poorly differentiated type (10 cases) 2) Anaplastic cell carcinoma (5 cases) 3) Basal cell carcinoma (0 cases) 4) Transitional cell carcinoma (0 cases) 5) Adenocarcinoma (1 cases) In 12 cases out of 28 specimens (43%) tumor cells were not found in histopathological serial sections In poorly differentiated squamous cell carcinoma, no tumor cells were found in 8 out of 10 cases (80%), in moderately differentiated type, in 1 out 3 cases (33%), in well differentiated type, in no case out of 9 (0%), and in anaplastic carcinoma, in 3 out of 5 cases (60%). In regard to "T" category of TNM classification, in 5 out of 7 cases (71, 70) tumor was free in T2 squamous cell carcinoma, but in only 4 out of 13 cases (31%) in T3. In T2 of poorly differentiated sqamous cell carcinoma and anaplastic caroinoma, the combined therapy is the treatment of choice, but in T3 it is recommended to be followed by some modified surgery with functional and cosmetic care in order to ascertain histologically no residual tumor after the combined therapy. In well differentiated squamous cell carcinoma radical operation of ample extent should be performed depending upon the staging of the tumor.View full abstractDownload PDF (681K) -
TEIZO MUKAI, TOSHIYUKI NISHIOKA, AKIO UYAMA1975 Volume 78 Issue 11 Pages 1177-1183
Published: November 20, 1975
Released on J-STAGE: July 31, 2008
JOURNAL FREE ACCESSA 50 years old newsman was complaining of sore throat and odynophagia since June 8, 1974. He was diagnosed as acute peritonsillitis on the left side. Slight swelling in the same side of the neck was also found. He was hospitalized on June 11. Urinalysis revealed glycosuria. The glucose tolerance test showed 242mg/dl blood sugar at 1 hour. On June 17, a crecipitation was proved in the region on the left side of the neck. About 10 ml white pus which looked like melted ice cream was removed by an incision and aspiration. Bacillus in the pus was identified as Clostridium perfringens by use of C W medium and the test paper, which contained the serum of the type A antitoxin. The fore chest with spreading suppurations was incised also. From both incised wounds the pus was continuously aspirated by low negative pressure. In the most serious condition, ca. 100ml pus, contained necrotic tissue was drained daily, resulting a large subcutaneous cavity formation in the neck and the fore chest. The lesion was treated locally by cleaning with Oxydol, pouring Lincomycin in the cavity and application of the solar lampe. Intravenous injection of the immune serum and the administration of aminobenzyl-penicillin and neomyson along with diabetic diet were effective in the treatment of this anaerobic bacillus infection in a diabetic.View full abstractDownload PDF (1500K) -
YASURO MIYOSHI, MASARU OHYAMA, FUSA IZUCHI, MIKIKAZU YAMAGIWA, YUICHI ...1975 Volume 78 Issue 11 Pages 1184-1192
Published: November 20, 1975
Released on J-STAGE: July 31, 2008
JOURNAL FREE ACCESSThe authors noticed the recovery of the nasal air current in the laryngectomized patients by connecting a tube between the tracheal stoma and the naris, so named this technique an artificial airway tube method. In this manner, the olfactory acuities of 60 laryngectomized patients, ranged from 9 days to 18 5/6 years postoperatively, were evaluated by measuring the detection threshold for the smell of various odors such as beta-phenyl ethyl alcohol, cyclotene and iso-valeric acid. At the same time we also measured respectively the onset and duration time for the sense of smell of Alinamin (Thiamine propyl disulfide) administered intravenously. Aside from the methods above mentioned, it is also known that swallowing of air leads a little olfactory sensation by nasal rout in some laryngectomized individuals. Thus utilizing airswallowing, olfactory testings by these 3 odors were undergone to guess their olfaction in daily life. Results obtained are summarized as follows; 1. The mean detection threshold for each of these 3 substances in the laryngectomized patients was nearly equal to that obtained in normal persons. While in the intravenous olfaction tests, more inferior data were seen in the laryngectomized patients than that of normal controls. Namely, not only the time needed for the onset of the sense of smell was twice longer, but also its duration shortened obviously as compared with their normal values.2. The best score was revealed in the subjects within one year after surgery in comparison with the others. 3. No significant differences of the olfactory acuities were observed between the groups, one with esophageal speech and the other with artificial voice apparatus. 4. When the laryngectomized patients put on the artificial airway tube, microclimate in the nasal cavity might be similar to that of normal one. 5. Olfactory sensation by swallowing procedure appeared in 40% of the laryngectomized patients in this series. But, the mean detection thresholds of individual odors were greatly higher than those obtained by the artificial airway tube method. For olfactory sensation, the longer the postoperative period, the more increased the incidence of its appearance.This study showed that the olfaction did not change in these patients. The assumption istherefore made that neurological changes in the terminal endings in this special sense organ do not occur after total laryngectomy.View full abstractDownload PDF (1829K)
- |<
- <
- 1
- >
- >|