耳鼻咽喉科臨床
Online ISSN : 1884-4545
Print ISSN : 0032-6313
ISSN-L : 0032-6313
101 巻, 7 号
選択された号の論文の14件中1~14を表示しています
  • 有病率と感作率について
    原田 保
    2008 年 101 巻 7 号 p. 491-498
    発行日: 2008/07/01
    公開日: 2011/10/07
    ジャーナル フリー
    Recently, it was reported that the incidence of Japanese cedar pollinosis has increased in Japan since 1990. In this study, specific IgE antibodies to Japanese cedar pollen were measured by the CAP method. The subjects were 1, 100 patients who visited the Allegergy Clinic of the Department of Otolaryngology, Kawasaki Medical School between 2000 and 2007. The sensitization rate was 62.7%. The percent positivity was highest in the 20-29 years old group, and decreased with age.
    From these findings, the nationwide prevalence of Japanese cedar pollinosis was estimated to be between 15 and 20%. In addition, the annual numbers of patients with Japanese cedar pollinosis was found to be been increasing. Further epidemiological studies in various regions are required to clarify the regional variation in the prevalence of cedar pollinosis.
  • 三浦 誠, 平海 晴一, 金丸 眞一, 宮崎 拓也, 石川 正昭
    2008 年 101 巻 7 号 p. 500-501
    発行日: 2008/07/01
    公開日: 2011/10/07
    ジャーナル フリー
  • 近藤 貴仁, 萩原 晃, 小川 恭生, 西山 信宏, 長谷川 達哉, 山田 哲也, 鈴木 衞
    2008 年 101 巻 7 号 p. 503-507
    発行日: 2008/07/01
    公開日: 2011/10/07
    ジャーナル フリー
    We report the case of a 45-year-old man with meningeal carcinomatosis who presented with bilateral progressive sensorineural hearing loss. The patient had been operated on for sigmoid colon cancer and lung cancer in 2006. He had experienced left hearing loss and left susurrus aurium since April 2007. Magnetic resonance imaging (MRI) revealed an enhanced mass in the left internal acoustic meatus, so we first suspected vestibular schwannoma. One month later, sudden sensorineural hearing loss developed on the other side. We examined the cerebrospinal fluid (CSF), and adenocarcinoma was detected. A diagnosis of meningeal carcinomatosis was made. With a history of malignant tumor, meningeal carcinomatosis should be considered as a cause of sensorineural hearing loss.
  • 一條 宏明
    2008 年 101 巻 7 号 p. 509-514
    発行日: 2008/07/01
    公開日: 2011/10/07
    ジャーナル フリー
    Peripheral positional vertigo is classified into the posterior semicircular canal type and the horizontal semicircular canal type. In the posterior canal type, rotatory nystagmus occurs on the Dix-Hallpike maneuver. The horizontal canal type demonstrates direction-changing horizontal nystagmus in a supine position with head turn. We classified horizontal canal positional vertigo into 3 types. Eighty-eight patients aged between 22 and 85 years (average age, 56.9 years; 65 women and 23 men) were studied. Each had direction-changing horizontal positional nystagmus, without evidence of neurologic disease. Nystagmus patterns were classified into three types: 1) apogeotropic type (nystagmus is always persistent, namely nystagmus lasts more than one minute), 2) persistent geotropic type (nystagmus lasts more than one minute), 3) transient geotropic type (nystagmus decays and stops within 30 seconds). Apogeotropic nystagmus was detected in 31 patients with 30 patients exhibiting the persistent geotropic type, and 27 patients the transient geotropic type. The apogeotropic type is explained by heavy debris cupulolithiasis of the horizontal semicircular canal. The pathophysiology of persistent geotropic type is considered a result of light debris cupulolithiasis of the horizontal semicircular canal. Transient geotropic type is explained by canalolithiasis of the horizontal canal.
  • 奥村 仁, 大滝 一, 高橋 姿
    2008 年 101 巻 7 号 p. 515-519
    発行日: 2008/07/01
    公開日: 2011/10/07
    ジャーナル フリー
    Rhinosporidiosis is a chronic granulomatous disease that commonly affects the nasal mucosa and ocular conjunctiva. The disease is endemic in southern India and Sri Lanka. In Japan, it is extremely rare, however, with a significant number of foreign workers from endemic regions, this uncommon disease may be observed more frequently in the future. Therefore, it is important to recognize the clinical features and pathogenesis of this disease.
    We recently managed a case of rhinosporidiosis that presented with left-sided epistaxis. The diagnosis was confirmed by histological examination. Wide surgical incision was performed and there was no recurrence during the follow-up period.
  • 川畠 雅樹, 福岩 達哉, 黒野 祐一
    2008 年 101 巻 7 号 p. 521-526
    発行日: 2008/07/01
    公開日: 2011/10/07
    ジャーナル フリー
    An 82-year-old man was referred to our hospital with bloody rhinorrhea on the right side of 3 months' duration. There was no history of bloody tears, nasal pain and nasal obstruction. On physical examination, a mobile and elastic soft mass was slightly palpable in the area of the right lacrimal sac. Nasal endoscopic examination revealed a soft reddish mass located in the right inferior nasal meatus. CT scan showed an enhanced soft tissue mass filling the right nasolacrimal duct from the orbit to the nasal cavity. There was no bone destruction. MRI showed a low-intensity mass on T1-weighted images and a high-intensity mass on T2-weighted images. The tumor was enhanced by gadolinium. A biopsy was performed from the tumor in the inferior nasal meatus. On histology, the tumor consisted of large cells with abundant granular cytoplasm and an oval nucleus, which formed a solid and occasionally trabecular pattern. These findings were interpreted as suspected acinic cell carcinoma. The tumor was excised en bloc by a right medial maxillectomy with lateral rhinotomy, removing the medial wall of the maxillary sinus and the medial part of the orbit. The resectioned dark-brown tumor was 4×10×8mm and possessed a well-defined capsule. Histrologically, the tumor was composed of large cells with abundant eosinophilic granular cytoplasm and an oval nucleus, which formed a solid and occasionally trabecular pattern. Neither nuclear atypia nor mitosis was found. Immunohistochemically, tumor cells were positive for antimitochondrial antibody, cytokeratin (AE1/AE3). The Ki-67 labeling index was <1%. Taken together, the tumor was diagnosed as oncocytoma. He remained disease free at 13 months' follow-up.
  • 本多 啓吾, 土師 知行
    2008 年 101 巻 7 号 p. 527-529
    発行日: 2008/07/01
    公開日: 2011/10/07
    ジャーナル フリー
    Sinonasal inverted papilloma is a benign but locally aggressive tumor with significant malignant potential. Incomplete resection of the tumor often results in local recurrence. On computed tomography, the tumor usually has soft tissue density. High-density areas within the tumor usually represent intratumoral calcification and intratumoral osteogenesis is extremely rare. To the best of our knowledge, only four cases have been reported so far. We report an additional case of sinonasal inverted papilloma with intratumoral osteogenesis. The patient was a 55-year-old Japanese female who presented with symptoms of acute sinusitis. Intranasal polypoid lesion was diagnosed as an inverted papilloma histopathologically. Computed tomography revealed a high-density area lying across the maxillary osteum. Endoscopic resection of the tumor was performed. Histopathological examination of the surgical specimen revealed metaplastic bone tissue surrounded by the tumor. Further investigations are required to elucidate the pathophysiological mechanisms of osteogenesis in inverted papilloma.
  • 長谷川 陽一, 服部 賢二, 宇野 吉裕, 岡崎 鈴代
    2008 年 101 巻 7 号 p. 531-534
    発行日: 2008/07/01
    公開日: 2011/10/07
    ジャーナル フリー
    Benign cartilaginous tumor of the larynx is an uncommon neoplasm comprising less than 1% of all laryngeal tumors. The most common region is the cricoid cartilage. In most reports, conservative surgery to preserve the larynx has been regarded as reasonable because of the slow growth of this tumor. We report a case of chondroma originating in the cricoid cartilage with review of the literature. A 72-year-old male was referred to our hospital because of dyspnea and hoarseness. Pulmonary function study demonstrated an obstructive pattern of the upper airway. CT scanning showed a subglottic mass involving the cricoid cartilage and laryngoscopy demonstrated a submucosal tumor. We resected the tumor with a laryngofissure approach. Consequently, the pathological diagnosis was laryngeal chondroma. Although this patient has not shown any reccurence to date, strict observation is required due to the high recurrence risk.
  • 茂木 英明, 林 景子, 工 穣, 宇佐美 真一
    2008 年 101 巻 7 号 p. 535-540
    発行日: 2008/07/01
    公開日: 2011/10/07
    ジャーナル フリー
    Cystic lymphangiomas are congenital malformations of the lymphatic system, such as benign tumors that may be seen in the neck of infants. Surgical therapy entails risk of complications, depending on the location and extent of the tumor. Therefore, alternative treatments such as sclerotherapy with OK-432, have been developed. We report here a case of cystic lymphangioma treated by ultrasonography (US)-guided percutaneous aspiration and intraregional injection of OK-432 under general anesthesia. The difficulty in this case was the location of the tumor, which contacted the trachea. If OK-432 were to induce an inflammatory response in the trachea, it could lead to tracheal stenosis and respiratory disturbances. Therefore, this case required endotracheal Intubation and mechanical ventilation after injection therapy for three days. OK-432 sclerotherapy is an effective treatment for cystic lymphangiomas in infants, and should be considered before surgical excision.
  • 野田 加奈子, 平野 隆, 松本 陽, 鈴木 正志
    2008 年 101 巻 7 号 p. 541-547
    発行日: 2008/07/01
    公開日: 2011/10/07
    ジャーナル フリー
    The CyberKnife is an image-guided frameless dedicated stereotactic radiotherapeutic device. This instrument is composed of a combination of a robot manipulator and LINIAC. Between January 2004 and August 2007, 11 patients with 15 malignant lesions of the head and neck were treated with this system because of tumor recurrence, difficulty in surgery or additional increase after external radiotherapy. Primary lesions were diagnosed in 8 cases. Of 8 these cases, 5 cases involved the paranasal sinus, 2 cases involved the temporal bone, and 1 case involved the parapharyngeal space. Metastatic lymph nodes were found in two cases and metastatic bone observed in one case. The response rate (CR+PR) was 13.3% and local control rate (CR+PR+SD) was 80.0%. Adverse events were assessed by the Common Terminology Criteria for Adverse Events (CTCAE) v. 3 (10/2004). Grade 3 was observed in three cases and grade 4 in one case. Our early experience indicates that CyberKnife is an effective treatment for local control of locally advanced or recurrent head and neck tumor, however adverse events are not rare.
  • 西池 季隆, 大崎 康宏, 入船 盛弘, 宇野 雅子, 粟飯原 輝人, 原田 保
    2008 年 101 巻 7 号 p. 549-553
    発行日: 2008/07/01
    公開日: 2011/10/07
    ジャーナル フリー
    We reviewed 9 patients with active pulmonary tuberculosis (TB) accompanying head and neck cancer. There were 5 patients with hypopharyngeal cancer, 2 with laryngeal cancer and 2 with tongue cancer. All patients were male and the mean age was 62 years old. TB detected simultaneously with the diagnosis of cancer was defined as “synchronous” and found in 4 patients, and TB that developed during the cancer course was defined as “secondary” and found in 5 patients. Two of the synchronous patients had a previous TB history and 3 of the secondary patients had a TB history. Bacteriologic cure was achieved within an average of 3 months. In one patient, TB relapsed 3 years after antitubercular chemotherapy. Seven patients died of malignancies, one died of other diseases and one has remained disease-free for 4 years to date.
  • 臼渕 肇, 太田 康, 金澤 丈治, 椿 恵樹, 飯野 ゆき子, 山田 茂樹
    2008 年 101 巻 7 号 p. 555-559
    発行日: 2008/07/01
    公開日: 2011/10/07
    ジャーナル フリー
    Group A streptococci may cause a variety of infections, some of which are severe and may be lifethreatening. Patients affected by severe invasive group A streptococcal infection may develop a syndrome characterized by circulatory insufficiency with multiple organ failure, namely, streptococcal toxic shock-like syndrome (TSLS). Here, we report a case of streptococcal TSLS originating from the left neck. A 70-year-old man was referred to our hospital with a diagnosis of deep neck and mediastinal infection. Debridement of his left neck and drainage of anterior and posterior parts of the mediastinum were immediately performed. As Group A streptococci were detected from the effusion and blood, he was diagnosed as having streptococcal TSLS. Intensive systemic care involving long-term administration of penicillin G in addition to drainage of the infection helped him recover from TSLS. He underwent further debridement twice to control local infection. Early diagnosis of and surgical intervention for TSLS are mandatory. Subsequently, appropriate supportive treatment of vital organ dysfunction and administration of penicillin as the antibiotic of choice represent the cornerstones of the management of this syndrome.
  • 久保 伸夫
    2008 年 101 巻 7 号 p. 560-561
    発行日: 2008/07/01
    公開日: 2011/10/07
    ジャーナル フリー
  • 磯野 道夫, 斉藤 和也, 村田 清高
    2008 年 101 巻 7 号 p. 562-563
    発行日: 2008/07/01
    公開日: 2011/10/07
    ジャーナル フリー
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