巻号一覧
前身誌
76 巻, 5 号
選択された号の論文の16件中1～16を表示しています
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ことに中耳滲出液について細見 泰敏, 後藤 まゆき, 山本 悦生, 一色 信彦1983 年 76 巻 5 号 p. 1377-1381
発行日: 1983/05/01
公開日: 2011/11/04
ジャーナル フリー口蓋裂患者の初回口蓋形成術施行時 (0～2才) と,二次手術施行時 (3～28才) に鼓膜穿刺を行ない中耳滲出液の有無を調べた.
(1) 0～2才では, 33%の中耳に粘稠な貯留液を認めた.
(2) 3～28才では, 7%の中耳に粘稠な貯留液を認めた.
(3) 中耳貯留液の培養により, その60%に細菌を検出した. 検出された細菌は, Staphyloccus aureus, α-haemolytic streptococcus, Streptococcus pneumoniae であった.
口蓋裂患者の中耳疾患発症には, 耳管咽頭口の細菌汚染が重要な役割を果たしているものと推測される.抄録全体を表示PDF形式でダウンロード (520K) -
梅谷 芳雄, 湊川 徹, 稲守 徹, 涌谷 治夫, 小笠原 寛, 雲井 健雄1983 年 76 巻 5 号 p. 1383-1390
発行日: 1983/05/01
公開日: 2011/11/04
ジャーナル フリーFive cases of carcinoma of the auditory canal and middle ear treated in the period from 1976 to 1981 at the Hyogo Medical College were presented. The primary site of one case was presumed to be in the middle ear and the other 4 were to be in the external auditory canal. Pathologically, one of them was an adenoid cystic carcinoma and the others were squamous cell carcinomas.
These patients were treated primarily with operation and radiation and chemotherapy were administered additionally. Although good results were obtained in 2 cases with chemotherapy, wide resection should be the first choice because it makes postoperative treatment easier.抄録全体を表示PDF形式でダウンロード (6460K) -
安斉 友博, 大槻 好正, 村上 正文, 今泉 秀雄, 大谷 巌, 大内 仁1983 年 76 巻 5 号 p. 1391-1397
発行日: 1983/05/01
公開日: 2011/11/04
ジャーナル フリー38才の男性で, 狩猟中の誤射により経外鼻孔的に蝶形骨洞まで達した銃弾異物の症例を報告した. われわれが調べた範囲では, 蝶形骨洞銃弾異物で経外鼻孔的に侵入した報告はなく, 極めて稀な侵入経路をとった症例と思われる. 併せて, 副鼻腔異物に関して若干の文献的考察を行った.抄録全体を表示PDF形式でダウンロード (3788K) -
谷 光毅, 山本 邦之1983 年 76 巻 5 号 p. 1399-1403
発行日: 1983/05/01
公開日: 2011/11/04
ジャーナル フリー56才の女性にみられた, 長期間にわたり存在したと考えられる鼻結石の1例を経験した. 結石の大きさは, 高径3.0×前後径3.6×横径1.6cm, 乾燥重量は約5gで, 燐酸カルシウム及び炭酸カルシウムを主成分としていた. 核となった物質は認められなかった.抄録全体を表示PDF形式でダウンロード (2054K) -
近藤 隆, 河辺 義孝1983 年 76 巻 5 号 p. 1405-1412
発行日: 1983/05/01
公開日: 2011/11/04
ジャーナル フリーFrom 1965 to 1978, we encountered 13 cases of carcinoma of the nasal cavity, which were statistically observed and found to be 6.7% of all the tumors of the nose and paranasal cavities.
Nasal cavity tumors are rather small in number, but they are pathologically quite rich in character. It has been revealed that nasal cavity tumors hold a special position in the classification of tumors. Adequate treatment for carcinomas of the nasal cavity demands a thorough evaluation of the site of origin and route of spread of the tumor.
Since these lesions tend to remain localized, the problem is principally one of local control of the disease. Failure to achieve local control seems to reflect initial underestimation of the extent of the disease. In general, nasal cavity tumors have favorable prognoses compared with the tumors of the paranasal sinuses. The five-year crude survival rate was 60.0%.抄録全体を表示PDF形式でダウンロード (881K) -
特に気象との関係について佐々木 〓, 朴沢 二郎, 福岡 敬二, 野沢 出, 川畑 武裕1983 年 76 巻 5 号 p. 1413-1422
発行日: 1983/05/01
公開日: 2011/11/04
ジャーナル フリーTwo hundred and twenty-eight patients of epistaxis were treated in Hakodate Municipal Hospital from July in 1980 to June in 1981. The patients' ages ranged from 0 to 70 years. There were 130 males and 98 females.
The origin of epistaxis was classified into local (37.1%), systemic (28.7%) and essential causes (34.2%). For these patients, the relation between the incidence of epistaxis and weather conditions was investigated. As a result, a high incidence of epistaxis was observed to be closely connected with the following three atmospheric factors: i) dryness of the air, ii) approach of low atmospheric pressure and iii) passage of a cold front.
In the Hakodate district, high incidences of epistaxis were observed in January and in the period from March to April when there were frequent passages of cold fronts accompanied by low atmospheric pressure.抄録全体を表示PDF形式でダウンロード (1032K) -
古川 仭, 石黒 英世, 石橋 陽二, 梅田 良三1983 年 76 巻 5 号 p. 1423-1426
発行日: 1983/05/01
公開日: 2011/11/04
ジャーナル フリーLaser surgery is an excellent surgical technique. We employed CO2 laser to remove the recurrent small cancerous tissue that developed in the post cricoidal area. The laser beam was irradiated via an operative microscope. At first, the focused beam was used for cutting the tumor and the defocused beam was employed subsequently to reduce the quantity of the tumor. Vaporization was useful for getting rid of the deeper part of the tumor.
No significant hemorrhage was observed during the operation.
However, because of delayed healing course of wound, a progressive necrotizing lesion occured after surgery. When the coating of necrotic tissue was detached spontaneously from the wound, massive bleeding happened and the patient died from shock. We discussed indications for laser surgery and pointed out factors which have close relations in healing of the wound.抄録全体を表示PDF形式でダウンロード (1789K) -
田辺 正博, 牛呂 公一, 楠本 健夫, 土師 知行, 辻田 達朗1983 年 76 巻 5 号 p. 1427-1434
発行日: 1983/05/01
公開日: 2011/11/04
ジャーナル フリーThe pectoralis major myocutancous island flap was used for head and neck reconstruction in six patients. Reconstruction was made on five of the patients following extirpative surgery of the oral cavity. The flap was also used in one patient for the reconstruction of a large defect in the submandibular region due to radiation necrosis. No loss resulted in any portion of the flaps in any of the patients. No complications were encountered.
The advantages of the pectoralis major myocutancous island flap are as follows. The flap has an excellent blood supply and is very reliable. Reconstruction can be performed in one stage. Large defects of tissue can be filled with the thick skin-subcutaneous-muscle complex. The muscle pedicle protects the carotid artery and restores the contour to the dissected neck. There is usually no need of skin grafting to the donor site.
The disadvantages of this flap are as follows. The thickness of the flap limits its use only to large tissue defects. The flap is problematic in cases with thick subcutaneous fat and muscle. The loss of the function of the pectoralis major muscle is inevitable. The bulkiness of the musule pedicle covering the neck has the potential of obscuring recurrent neck disease.
Although, this flap will probably become more commonly used, there may still be cases in which regional or other skin flaps are preferable to this flap.抄録全体を表示PDF形式でダウンロード (5296K) -
ゲンタマイシンを中心に斎藤 等, 上出 一朗, 小野 寿之, 中江 進, 平杉 嘉昭1983 年 76 巻 5 号 p. 1435-1452
発行日: 1983/05/01
公開日: 2011/11/04
ジャーナル フリーComparative ototoxicity and nephrotoxicity studies of gentamicin between 60-minute intravenous infusion and intramuscular administration were carried out using a total of 36 rabbits. The following results were obtained:
At the dose of 30mg/kg, there was no difference in ototoxicity and nephrotoxicity between 60-minute intravenous infusion and intramuscular administration.
At the dose of 40mg/kg, almost similar ototoxicity was observed via both administration routes. However, deaths that are considered attributable to nephrotoxicity were found in more animals in the 60-minute intravenous infusion group than in the intramuscular administration group. This result indicates that the risk of ototoxicity may be secondarily increased by a retarded excretion of gentamicin.
The dose of 40mg/kg was considered to be the threshold to develop significant nephrotoxicity and ototoxicity by 60-minute intravenous infusion.抄録全体を表示PDF形式でダウンロード (7960K) -
柳原 弘男1983 年 76 巻 5 号 p. 1453-1470
発行日: 1983/05/01
公開日: 2011/11/04
ジャーナル フリーThe initial part of the present investigation clarified the relationship between hearing impairment and the pathology of the cochlea in experimentally-induced round-window membrane (RWM) rupture. The auditory brain stem response (ABR) was employed to assess hearing of the animals. In 15 (56%) of the 27 guinea pigs, hearing loss immediately after the rupture remained within 10dB. In these animals, there was no injury of the organ of Corti, despite hemorrhage in the perilymphatic space. In 4 of the 7 animals which survived from 7 to 100 days, during which hearing loss was within 10dB immediatery after the rupture of the RWM, no further deterioration of hearing ensued, and there was no specific pathologic change in the cochlea except for hemorrhage of the perilymphatic space. The results indicated that the RWM rupture alone might not cause serious hearing impairment as long as the organ of Corti remained intact.
In the latter part of the present study, comparative histological study of the healing process of the RWM ruptures was performed in 13 guinea pigs using the fascia and the perichondrium. After the RWM was totally ruptured, it was closed with the temporal fascia in 6 guinea pigs and with the perichondrium in 7. One to three months after surgery, histological specimens of the RWM were obtained. Either the temporal fascia or perichondrium seemed to function as a “supporting guide” in closure of the RWM and the healing process of the RWM rupture with these materials were essentially the same. Complete absorption of these materials usually took three months.抄録全体を表示PDF形式でダウンロード (12570K) -
関根 修二1983 年 76 巻 5 号 p. 1471-1479
発行日: 1983/05/01
公開日: 2011/11/04
ジャーナル フリー前庭眼反射(VOR)利得と左右逆転視プリズム1時間装着による利得の変化(適応現象)およびプリズム除去後の利得変化におよぼす年令の影響を, 5才から79才までの健常者80 名について観察した.暗所遮眼下の平均利得は, 5～9才群で0.84と最も高く,加令とともに漸次減少し, 30才代群で0.59と最も低く, 再び加令とともに利得は高値となり, 70才代群で0.77であった. 一方, 逆転視プリズムによるVORの適応現象とプリズム除去後の回復過程については年令の変化をうけず, 暗所遮眼下のVOR利得を基準とすると, 各年代群間に有意の差は認められなかった. このことから暗所遮眼下のVOR利得に対する年令変化は, 30才代まではヒトの生活環境下における視覚入力と前庭入力の不一致からくるVORの可塑的な変化 (学習) が主に関与し, 30才代以降は, この学習が減少しプルキンエ細胞の数の減少等の加令による変化が前面に出てくるものと推測された. 左右逆転視プリズム装着によるVORの適応現象は, 年令変化を受けておらず, 暗所下のVOR利得の制御機構と適応現象が異った解剖学的局在を有していることが推測された. さらにVORの適応現象が年令変化をうけないことは, これを臨床検査として用いる場合に有利な条件となる.抄録全体を表示PDF形式でダウンロード (964K) -
第1報: 中耳粘膜および耳管における神経ペプチド分布二之湯 修, 山下 敏夫, 天野 一, 久保 伸夫, 熊沢 忠躬1983 年 76 巻 5 号 p. 1481-1489
発行日: 1983/05/01
公開日: 2011/11/04
ジャーナル フリー中耳粘膜及び耳管における神経ペプチド分布を蛍光抗体法及びPAP法により観察した.中耳粘膜については, SP, VIP, APP, GRP, 各ペプチド神経線維の分布を調べた.神経線維のほとんどは微小血管に沿ってみられたが,中には独立して走行する神経線維もみられた. SP, VIP, APP, 3種のペプチド神経線維は,中耳粘膜において多く分布していたが, GRP神経線維については, その分布は全体的に少なかった.中耳腔内分布において, 4種のペプチド神経線維は,耳管鼓室口附近に多く鼓室口より遠ざかるにつれて,その分布は少なくなる傾向がみられた.
耳管におけるペプチド神経線維の報告はすでにVIPそしてAPPに関して調べられているが, 今回著者らは蛍光抗体法及びPAP法により耳管におけるSP神経線維分布を調べ得たので報告した. SP神経線維は耳管鼓室口より中央部にかけて少なく, 耳管咽頭口附近に多く分布していた. 粘膜下そして血管周囲にその分布を多く認めたが, 耳管腺周囲には少なかった.
上頸神経節除去により中耳粘膜におけるAPP神経線維は消失したが, SP, VIP, GRP, 各神経線維は影響を受けなかった. 中耳粘膜及び耳管に見出された各ペプチド神経線維は血管拡張, 血流増加作用及び分泌亢進作用があると言われており, それらは従来のアドレナリン作動神経線維, コリン作動神経線維と共同して耳管を通しての通気性の維持をして中耳における感染防禦及び異物除去作用などに影響しているものと勘案した.抄録全体を表示PDF形式でダウンロード (4251K) -
水野 正浩, 木村 徹男, 宮田 守, 森田 守1983 年 76 巻 5 号 p. 1491-1498
発行日: 1983/05/01
公開日: 2011/11/04
ジャーナル フリーThe clinical effects of Cerocral were studied on 16 patients with peripheral vertigo principally Meniere's disease, and these effects were assessed by subjective and objective parameters. The results obtained were as follows;
(1) Cerocral was effective in 80% of patients.
(2) As to the subjective symptoms, the frequency and intensity of vertigo and nausea and/or vomitting were prominently improved, and tinnitus, headache and shoulder stiffness were comparatively improved.
(3) As to the objective parameters, the stepping test and positional nystagmus test were also prominently improved.
(4) No sereous side-effects were observed.
Thus, Cerocral seemed to be effective and safe for treatment of peripheral vertigo.抄録全体を表示PDF形式でダウンロード (738K) -
玉田 彰, 加納 直行, 大川 正直, 野々村 光栄, 由井 正剛, 牧本 一男1983 年 76 巻 5 号 p. 1499-1504
発行日: 1983/05/01
公開日: 2011/11/04
ジャーナル フリーLM 209 is a new product of antihistamine to treat allergic diseases. We investi-gated the antiallergic activity of LM 209 for allergic rhinitis, using 24 patients appeared in the ENT clinic of Kyoto University Hospital and Nagahama Red Cross Hospital from Spring to July, 1982. This drug was given to each patient for 3 weeks continuously. The results obtained were as follows.
1) The effectiveness for sneezing, watery rhinorrhea and nasal obstruction was 79.2, 66.7 and 33.3% respectively.
2) Overall effectiveness for allergic rhinitis was 66.7%, including seasonal and perennial types.
3) The side effect of drowsiness and tiredness was minimal, for which a long term administration was feasible.抄録全体を表示PDF形式でダウンロード (521K) -
アズノール®錠との二重盲検比較試験原田 康夫, 夜陣 紘治, 築家 大介, 竹内 實, 野田 益広, 北澤 式文1983 年 76 巻 5 号 p. 1505-1515
発行日: 1983/05/01
公開日: 2011/11/04
ジャーナル フリーIn order to evaluate the efficacy of AZ-S tablets (GASN 5mg) on pharyngitis, a double blind test was performed with AZ-U gargle tablets (GASN 2mg) as a control. The subjects were 45 patients with pharyngitis for AZ-S and 48 for AZ-U. All the AZ-S tablets were administered into the labiogingival region of the upper jaw.
1. AZ-S tended to be more effective for spontaneous pain and reddness of the pharyngeal mucous membrane than AZ-U (p<0.10). AZ-S was significantly more effective for swelling and discomfort in the pharynx (p<0.05).
2. Pharyngitis was cured in significantly shorter periods with AZ-S than with AZ-U (p<0.05).
3. Overall efficacy tended to be superior with AZ-S tablet (p<0.10).
4. No obvious side effect attributable to AZ-S or AZ-U was observed.
5. From the above results, AZ-S tablets administered into the labiogingival region of the upper jaw was considered to be more effective for pharyngitis than AZ-U gargle tablets.抄録全体を表示PDF形式でダウンロード (1171K) -
山際 幹和, 福生 治城, 坂倉 康夫, 三吉 康郎1983 年 76 巻 5 号 p. 1517-1529
発行日: 1983/05/01
公開日: 2011/11/04
ジャーナル フリーSaikokaryukotsuboreito is a prescription of crude drugs and mainly contains pinelliae and magnolia. It has been used for the therapy of men with abnormal sensation in the throat in Kanpo medicine (Chinese traditional medicine inherited and developed in Japan).
The authors administered Tsumura-Saikokaryukotsuboreito (7.5g daily for two weeks) to a consecutive series of 50 male patients and evaluated the efficacy of the drug by analysing the patients' subjective signs and symptoms.
The drug was effective in 56% of the patients in a week, for 64% in 2 weeks and for 72% in 3 weeks (one week after the cessation of the drug). Side effects were minimal, and only one patient reported anorexia.
It was indicative that modern and traditional medicine combined might produce a higher rate of efficacy and usefulness in the therapy of abnormal sensation in the throat.抄録全体を表示PDF形式でダウンロード (1547K)
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