耳鼻咽喉科臨床
Online ISSN : 1884-4545
Print ISSN : 0032-6313
ISSN-L : 0032-6313
81 巻, 9 号
選択された号の論文の21件中1~21を表示しています
  • 設楽 哲也
    1988 年 81 巻 9 号 p. 1251-1255
    発行日: 1988/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    Adequate medical treatment of malignant tumors in the oral cavity is most important in the management of otorhinolaryngological diseases.
    The methods of treatment in current use are laser therapy, irradiation, total removal of the tumor by surgery, reconstructive operation, chemotherapy, immunological approach and various combinations of these.
    “Five year cure-rates” with these procedures are better than in the past, but it is necessary to promote both early diagnosis and early treatment to gain much better results.
    Otolaryngologists play the most important role in the management of malignant tumors of the oral cavity, and they should be responsible for both earlier diagnosis and earlier therapy. Therefore, all otolaryngologists should know about all the diseases of the oral cavity.
  • ―その臨床応用―
    川端 五十鈴, 堀口 利之, 近藤 玲子
    1988 年 81 巻 9 号 p. 1256-1257
    発行日: 1988/09/01
    公開日: 2011/11/04
    ジャーナル フリー
  • ―教室15年間の検討から―
    岡本 牧人, 設楽 哲也, 古沢 慎一, 平山 方俊
    1988 年 81 巻 9 号 p. 1259-1266
    発行日: 1988/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    Six hundred patients with sudden deafness visiting Kitasato University Hospital during the past 15 years were divided into two groups: group I, 150 seen in the past three years and group II, 450 seen in the previous 12 years.
    There was no statistically significant difference in sex or incidence of vertigo between the two groups. Younger and older patients were significantly more numerous in group I. The interval between onset of symptom and first hospital visit was longer in group I than in group II. The average hearing level was equal in patients who visited our hospital within four days after the onset of symptom, but among patients whose first visit was later, the average hearing level was better in group I than in group II. These facts point to the improvement of diagnosis and treatment of sudden deafness among general otologists, as a result of research and information about sudden deafness by the Intractable Diseases Research Commitee of the Ministry of Health and Welfare of Japan. It is now easy for most general otologists to diagnose and treat this desease, so patients receive primary care for several days before being referred to our hospital for secondary treatment.
    The number of cured and definitely improved patients has increased significantly. On the other hand, 20% of the patients in both groups did not show improvement. We must continue to work to improve the rate of cure and to define the cause and pathology of this disease.
  • 川上 友美, 永田 誠治, 川上 理郎, 奥村 雅史, 牧本 一男, 高橋 宏明
    1988 年 81 巻 9 号 p. 1267-1271
    発行日: 1988/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    A rare case of simultaneous bilateral sudden deafness in a 58-year-old female with diabetes mellitus is presented.
    She visited Hokusetsu General Hospital with complaints of sudden bilateral hearing disturbances and right tinnitus. She had had poorly controlled diabetes mellitus three years. Several treatments, including medications for diabetes mellitus led to for very good recovery of hearing improvement in the right ear, but only slight improvement in the left ear.
    Our experience with this case and a review of the literature indicate that in sudden deafness secondary to diabetes mellitus there are various etiologic mechanisms, such as metabolic dysfunction of the stria vascularis, changes of endolymphatic osmotic pressure, sludging of blood cells, vasospasm and abnormalities of the vessels in the cochlea.
    Further clinical and experimental studies are needed to elucidate the pathophysiology of sudden hearing impairment in patients with diabetes mellitus.
  • 伊藤 信輔, 久冨 圭子, 井上 望, 山口 勝矢, 渡辺 慈之
    1988 年 81 巻 9 号 p. 1273-1276
    発行日: 1988/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    A sensitive method of demonstrating latent imbalance of labyrinthine function was devised. The subject was asked to walk at his usual speed with eyes closed in a circle 2 meters in diameter. This test was given to 22 patients whose vestibular function as tested by the Romberg, Mann, Fukuda and Babinski-Weil's methods had become normal after an attack of vertigo due to unilateral vestibular disease. Eighteen patients complained of difficulty in walking, and 11 tended to fall to the inside of the circle while turning to the affected side. It was thought that disorders of the cristospinal reflex became manifest during this circular walk.
  • 熊川 孝三
    1988 年 81 巻 9 号 p. 1277-1284
    発行日: 1988/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    The author investigated high-resolution MR imaging (MRI) of the inner ear and evaluated its usefulness in the selection of patients for cochlear implants. MRI was performed with a 1.5T unit with the use of the head coil. The minimum thickness of the sections was 2.5mm. T1-and T2-weighted images were obtained. The matrix size was 256×256, and the field of view was 15cm. ECG-gating was introduced to eliminate motion artifacts.
    T2-weighted images could clearly delineate details of liquid containing labyrinth structures, including the cochlea, the vestible, the semicircular canals, and the internal auditory canal. With the proper use of T1 and T2 sequences, tissue characterization between lymph fluid and soft tissue could be obtained. This point was considered to be one of the greatest advantages of MRI over high-resolution CT in the diagnosis of inner ear disorders. The head coil technique seems to be superior to the surface coil technique in that it can generate homogeneous signal intensity, and therefore visual comparison of cochlea signals of both sides is possible under the same conditions.
    The author concluded that high-resolution MRI of the inner ear is useful for the preoperative assessment of cochlear implant candidates in order to rule out soft tissue occlusion of the cochlea, which cannot be diagnosed even by high-resolution CT.
  • 本山 壯一, 井上 功, 牧本 一男, 高橋 宏明, 大野 正博
    1988 年 81 巻 9 号 p. 1285-1293
    発行日: 1988/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    We describe four patients with acute sinusitis which developed in the intensive care unit following the long term use of intubation tubes or nasogastric tubes. They had fever and leukocytosis which started 8 to 25 days after insertion.
    CT scans revealed sinusitis in all four cases. In two patients, the lesions were seen recognized only in a maxillary sinus, while the remaining two showed evidence of pansinusitis, one had bilateral sinusitis. Cultures of maxillary discharge grew out staphylococcus aureus, peptostreptococcus, candida albicans and citrobacter freundii. All four cases were treated with antral puncture and sinus irrigation, and definite improvement of acute sinusitis was documented. Intubation tubes and feeding tubes in the nasal cavities may be considered one of the etiologic factors leading to acute sinusitis. In this regard, in the clinical courses of such ICU patients with persistent fever of unknown origin and/or leukocytosis, acute sinusitis should be kept in mind as possible of infection.
  • 高橋 正紘, 伊藤 光子, 石井 純子
    1988 年 81 巻 9 号 p. 1295-1300
    発行日: 1988/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    Surgical methods (instruments and techniques), surgical anatomy and indications for rhino-microsurgery are described. A self-retaining retractor speculum facilitates bimanual operation under a microscope. Microsurgery proved to be very useful for attaining magnification, safety and selective surgery as well as avoiding extranasal operations. The relationship between the viewing axis of the microscope and the patient's head is important to determine the fields of operation. As landmarks for opening the sinuses, we used the anterior wall of the sphenoid sinus, the funnel of the orbit and the posterior end of the middle turbinate. The microscopic intranasal operation, being safe and cosmetically excellent, is appropriate for treating the most posterior part of the sinuses.
  • ―RAST・皮内反応の問題点―
    橋口 一弘, 小川 浩司, 山崎 嘉司, Claudia Kita, 都築 達
    1988 年 81 巻 9 号 p. 1301-1306
    発行日: 1988/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    Radioallergosorbent test (RAST), skin test and nasal challenge (provocative) test are used to identify allergen of nasal allergy. We have compared the results of tests to evaluate the methods and to establish appropriate indications for their use.
    House dust extract is a mixture of numerous allergenic components, mainly mites' component, so there seems to be a close correlation between sensitivities to house dust and mites. One hundred and sixty-two patients were tested with a battery of Dermatophagoides pteronyssinus (D1), Dermatophagoides farinae (D2), house dust by Greer Labos (H1), and house dust by Hollister-Stier Labos. (H2) We found 96% agreement of IgE antibodies to D1 and D2, 92% agreement for D2 and HI and 95% agreement for H1 and H2. We performed provocative tests with house dust by Torii Co. in Japan in 16 skin test-positive but RAST-negative and one skin test-negative but BAST-positive individuals. Twelve of these 17 patients had a nasal response. These results show that house dust in Japan probably contains more components of mites than does that in the United States.
    In cases of Japanese cedar (Cryptomeria japonica) pollinosis, there is much closer correlation between skin tests and RAST. Thirteen RAST-negative but skin testpositive patients had seasonal symptoms.
    RAST shows no false positive but sometimes shows false negative results.
    It therefore follows that RAST should be ordered only after a careful history and physical examination. As a screening test, RAST is too expensive, and excessive use of it should be condemned.
  • 浅井 俊治, 市川 銀一郎, 深間 内厚子, 内田 利男, 高川 直樹
    1988 年 81 巻 9 号 p. 1307-1311
    発行日: 1988/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    An 88-year-old female complained of mild dyspnea. A tumor was seen hanging over the mesopharynx. It measured 1.8×1.5×1.0cm and arose from the middle area of the right tonsil. Histopathological examination of the tumor showed abcess formation and acute inflammation with no evidence of malignancy. Five other cases reported from 1984 to 1986 year were reviewed. They were all younger than our patient.
  • 渡辺 祐介, 丹羽 英人, 服部 琢, 横井 久, 柳田 則之
    1988 年 81 巻 9 号 p. 1313-1318
    発行日: 1988/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    Fibromatosis is a benign tumorous condition of the soft tissues arising from musculoaponeurotic structures of the body. The commonest site of origin is the anterior abdominal wall. It is rarely seen in the facial region. Some of them are locally aggressive and have a high recurrence rate, following inadequate resection.
    We report a case of 30-year-old female who had presented with a history of increasing painless exophthalmos and diplopia of the right eye. CT scan revealed involvement of the orbit, paranasal sinuses and pterygopalatine fossa on the right side. The tumor was removed surgically with preservation of the eye ball. The post operative course was uneventful, with no recurrence 18 months later. Pathological examination showed that the collagenous matrix was dominated by mature fibroblasts, which was diagnostic of fibromatosis.
  • 菊地 茂, 喜多村 健, 浅井 昌大, 菅澤 正
    1988 年 81 巻 9 号 p. 1319-1326
    発行日: 1988/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    We describe three cases of intravagal paraganglioma and review the literature on clinical and histological findings and treatment. Our patients ranged in age from 36 to 46 years (mean, 40 years old); two males and one female.
    All three patients had a large parapharyngeal mass, and paralysis of the reccurent laryngeal nerve was noted in two of them. At surgery the tumors were found to be very close to the vagus nerve. However, the carotid bifurcation was not widened. Postoperative irradiation (60 Gy) was performed in one case because the tumor was unresectable. All tumors demonstrated similar histological characteristics. They were highly vascularized and had prominent hyalinized collagenous septa. An alveolar pattern was produced by the reticulin network. Each tumor cell had an ovoid or round nucleus and eosinophilic cytoplasm. Cytoplasmic argyrophil granules were demonstrated by the Grimelius stain, proving the tumors to be paragangliomas.
  • 籾山 安弘, 西端 慎一, 藤野 明人, 高橋 廣臣
    1988 年 81 巻 9 号 p. 1327-1332
    発行日: 1988/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    Twenty five cases of head and neck hemangioma are reviewed. These patients were treated at Kitasato University from 1971 to 1984.
    Histopathological examination revealed capillary hemangiomas (15 cases), cavernous hemangiomas (9 cases) and venous hemangioma (1 case). Capillary hemangiomas were found on the tongue and in the nasal cavity, and cavernous hemangiomas were found in the submandible and buccal subcutaneous tissue.
    The majority of the patients with cavernous hemangiomas were teenagers. Capillary hemangiomas were found in the fifth and sixth decades. There were no sexual difference.
    Five patients had phlebolithiasis in the subcutaneous tissue of the neck and cheek. The total number of hemangiomas in these regions was eight in this series, a higher incidence than in previous reports. Histopathologically, these five cases of phlebolithiasis were cavernous hemangiomas.
    Our experience with these cases confirms that soft X-ray examination is useful in the diagnosis of phlebolithiasis.
  • 古田 康, 川浪 貢, 飯塚 桂司
    1988 年 81 巻 9 号 p. 1333-1338
    発行日: 1988/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    The authors describe a patient who presented with recurrent chest pain during chemotherapy with 5-fluorouracil (5-FU).
    A 69-year-old man with metastatic lung carcinoma received 5-FU 1500mg/day by continuous infusion for 5 days. He developed chest pain during the second and third courses of 5-FU infusion, but there were no ischemic changes on the electrocardiogram.
    Cardiotoxicity as a rare side effect of 5-FU therapy has been reported, but its etiology remains unclear. The ischemic chest pain and EGG changes observed in most cases suggest that coronary artery spasm may be the cause of 5-FU cardiotoxicity. Although cardiotoxicity is a rare complication of 5-FU therapy, the authors think it is advisable to stop the treatment when chest pain occurs.
  • ―内耳窓破裂の発症機転の検討―
    西原 信成, 暁 清文, 柳原 尚明
    1988 年 81 巻 9 号 p. 1339-1344
    発行日: 1988/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    The inner ear pressure (PIE) in response to pressure changes in the external ear canal was measured in guinea pigs during opening and closing of the fenestrum of the otic bulla. Opening of the bulla caused only a transient change in the PIE, and the PIE was lower than when the bulla was closed, because the applied pressure was transmitted to the inner ear exclusively via the ossicular chain. When the otic bulla was closed, the pressure was transmitted not only via the ossicular chain but also via the round window through the middle ear cavity. When the bulla was closed, the PIE was increased more by a positive pressure load than by a corresponding negative one. The PIE showed a linear relationship to the ear canal pressure at least within ±200 mmH2O, as long as pressure was applied slowly to the ear canal. When the loading pressure was changed abruptly, a bouncing response, possibly reflecting elasticity of the round window, was evoked. It diminished or disappeared when the round window was ruptured artificially.
  • 蔡 一龍
    1988 年 81 巻 9 号 p. 1345-1356
    発行日: 1988/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    Since the development of conservation laryngeal surgery and the advent of computed tomography (CT) scanners, a precise preoperative evaluation of the extent of laryngeal cancer has been of prime importance.
    Eight patients with known carcinoma of the larynx were examined with CT of the larynx prior to surgery, and whole-mount serial sections of the extirpated larynx were compared with the corresponding level of CT sections to evaluate the reliability of CT during my study abroad in Japan from Dec. 1985 through Dec. 1986.
    1. The results indicated that CT scanning accurately delineates the anatomic location and pathologic extent of the tumor three-dimensionally in all cases examined. There is also good demonstration of the anterior commissure and preepiglottic, paraglottic and subglottic spaces which are sometimes poorly seen by laryngoscopy or by any other means.
    2. Determination of invasion of the laryngeal cartilage by tumor proved to be very difficult to diagnose with CT.
    3. The CT images obtained while the patient is breathing quietly, coupled with additional sections at the level of the vocal cord during slight valsalva maneuver afford good visualization of laryngeal tumors.
    4. It should be emphasized that a thorough pathologic examination of extirpated specimens with serial sections is essential for laryngeal surgeons, because it is impossible to determine the patient's prognosis without microscopic demonstration of the degree of invasion.
  • 辻久 茂, 矢野 一彦, 行木 英生, 吉原 重光, 渡辺 健二, 上原 美貴, 藤原 隆行
    1988 年 81 巻 9 号 p. 1357-1370
    発行日: 1988/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    We studied the clinical effect and safety of AA-673 (25mg) tablets in 84 patients with perennial allergic rhinitis at 4 institutions. The patients received a 25mg tablet of AA-673 three times daily for at least 4 weeks.
    The final global improvement rating showed “moderate to marked improvement”in 42% of the patients, and “slight to marked improvement”in 76%. The global improvement rate rose from two weeks to four weeks after the start of the administration. Subjective improvement of sneezing attacks, nasal discharge and nasal obstructaon was reported by 50%, 58% and 51% of the patients, respectively.
    Side effects, observed in 7 patients (8.3%), were all mild and transient.
    We consider AA-673 (25mg) tablets to be effective for the treatment of peren-nial allergic rhinitis.
  • 高安 勧次, 香取 早苗
    1988 年 81 巻 9 号 p. 1371-1382
    発行日: 1988/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    The therapeutic value of MOXYL, a post-synaptic al-blocking agent in cases of vertigo due to vertebro-basilar insufficiency was evaluated in an 8-week administration to 30 patients.
    1) The overall improvement rate was 89.7%. The drug appears to be effective regardless of age.
    2) It was especially effective in patients with a short duration of disease. However, adequate efficacy can also be expected in cases with long-standing disease.
    3) The clinical drug effects has the characteristics of a rapid onset of action, extensive efficacy, and quick symptom reversal.
    4) Only one patient experienced a side effect.
    These results indicate that MOXYL is a very useful drug and is the drug of choice for vertigo due to vertebro-basilar insufficiency.
  • 佐藤 宏昭, 中村 一, 本庄 巖, 藤田 明彦, 高橋 晴雄, 林 正彦
    1988 年 81 巻 9 号 p. 1383-1387
    発行日: 1988/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    The clinical usefulness of Tsumura-Saireito, which was judged by tympanoaudiometric tests, was compared with that of cepharanthin in 64 ears of 42 children with otitis media with effusion. The trial was a randomized controlled study.
    The efficacy rate for the 32 ears treated with Tsumura-Saireito was 43.8% and that for the 32 ears treated with Cepharanthin was 18.8%; the difference was significant (p<0.05). No side effects were observed in either group.
    These results indicate that Tsumura-Saireito is more effective in children with otitis media with effusion than Cepharanthin.
  • 村田 清高
    1988 年 81 巻 9 号 p. 1388-1389
    発行日: 1988/09/01
    公開日: 2011/11/04
    ジャーナル フリー
  • 1988 年 81 巻 9 号 p. e1
    発行日: 1988年
    公開日: 2011/11/04
    ジャーナル フリー
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