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92 巻, 4 号
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植田 尚男, 野口 愃, 内田 實1999 年 92 巻 4 号 p. 329-332
発行日: 1999/04/01
公開日: 2011/11/04
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植田 尚男, 野口 愃, 内田 實1999 年 92 巻 4 号 p. 329a-332
発行日: 1999/04/01
公開日: 2011/11/04
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太田 成彦1999 年 92 巻 4 号 p. 333-334
発行日: 1999/04/01
公開日: 2011/11/04
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松尾 聡1999 年 92 巻 4 号 p. 334-335
発行日: 1999/04/01
公開日: 2011/11/04
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沖中 芳彦1999 年 92 巻 4 号 p. 335-337
発行日: 1999/04/01
公開日: 2011/11/04
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高野 信也1999 年 92 巻 4 号 p. 337-339
発行日: 1999/04/01
公開日: 2011/11/04
ジャーナル フリーPDF形式でダウンロード (347K) -
―鼻アレルギーと慢性副鼻腔炎の比較―竹野 幸夫, 夜陣 紘治1999 年 92 巻 4 号 p. 339-341
発行日: 1999/04/01
公開日: 2011/11/04
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―エアロゾルの副鼻腔への移行―鈴木 賢二1999 年 92 巻 4 号 p. 341-343
発行日: 1999/04/01
公開日: 2011/11/04
ジャーナル フリーPDF形式でダウンロード (3229K) -
北野 博也, 藤 村昌樹1999 年 92 巻 4 号 p. 344-345
発行日: 1999/04/01
公開日: 2011/11/04
ジャーナル フリーPDF形式でダウンロード (2590K) -
古川 朋靖, 渡辺 道隆, 正木 義男, 都丸 香緒, 山口 洋子, 市川 銀一郎1999 年 92 巻 4 号 p. 347-354
発行日: 1999/04/01
公開日: 2011/11/04
ジャーナル フリーThe main clinical findings of OPCA include cerebellar symptoms, extrapyramidal symptoms, autonomic nerve symptoms, in addition to various oculo-motor disturbances. We reported a case of OPCA where neuro-otological examination facilitated the diagnosis. Neuro-otological examination was carried out in 6 cases of OPCA, and duration of illness and experimental findings were compared.
Subject: Neuro-otological examination was undertaken in 6 OPCA patients over a 5 year period 1993-1997. The mean patient age was 53.8 years, and the ratio of males to females was 2:4. Duration of illness was 3 years for 2 patients, 4 years for 2 patients, 6 years for 1 patient and 8 years for 1 patient.
Method: For all patients, the following examinations were carried out. (1) audiogram, ABR (2) nystagmus (3) eye tracking (4) optokinetic nystagmus, saccade (5) visual suppression.
Results: Smooth pursuit eye movement impairment was independent of the duration of illness. Nystagmus findings, saccadic eye movement and the visual suppression test revealed that impairment increased in patients whose duration of illness was more than around 4 to 6 years. The oculo-motor disturbances of OPCA start with impairment of cerebellar and smooth pursuit eye movement, and eventually result in brainstem disorders such as saccadic eye movement and visual suppression. As the duration of illness lengthens, the oculo-motor system itself will no longer function and response to all of the examinations will be lost. Neuro-otological examinations were found to be valuable for the diagnosis of OPCA.抄録全体を表示PDF形式でダウンロード (1107K) -
及川 敬太, 安藤 敬子, 佐藤 公輝1999 年 92 巻 4 号 p. 355-361
発行日: 1999/04/01
公開日: 2011/11/04
ジャーナル フリーSuperficial leiomyosarcoma is rarely encountered in the head and neck area. We report the rare case of a 63-year-old woman with superficial subcutaneous leiomyosarcoma in her retroauricular region. We performed wide local excision, and covered the surgical defect using a posterior scalp flap.抄録全体を表示PDF形式でダウンロード (10145K) -
石永 一, 加藤 昭彦, 山田 弘之1999 年 92 巻 4 号 p. 363-366
発行日: 1999/04/01
公開日: 2011/11/04
ジャーナル フリーThirty-six patients with epistaxis requiring hospitalization evaluated over the previous five years were statistically. Twelve patients could not be controlled by the conventional packing method. Ligation of the ethmoidal arteries was perfomed in 4 cases, selective catheter embolization in 5 cases, and turbinectomy and electro-cauterization in 3 cases. In one patient treated by ligation of the ethmoidal artery, and in four patients treated by selective catheter embolization, control of epistaxis failed. All 4 patients were subsequently treated by turbinectomy and electro-cauterization. Because of its relative simplicity and effectiveness, turbinectomy from the infra turbinal posterior end is proposed as the standard method for treatment of epistaxis. Ligation of the ethmoidal arteries should be used for the treatment of epistaxis originating from the olfactory cleft, and selective catheter embolization for treatment of those cases in which the bleeding points were undetectable.抄録全体を表示PDF形式でダウンロード (564K) -
向井 將, 向井 千珈子1999 年 92 巻 4 号 p. 367-373
発行日: 1999/04/01
公開日: 2011/11/04
ジャーナル フリーFrom August 1980 to November 1984 we experienced six cases of systemic reactions during pollen immunotherapy out of a total of fifty-three cases treated.
Case 1 was a 27 year old female. Ten minutes after injection with 0.05ml of a 1:1000 dilution of ragweed and with 0.2ml of 1:100 cedar, she went into anaphylactic shock. She recovered in approximately one hour following steroid therapy. Case 2 was a 38 year old female. Coughing and itching appeared about one hour after the injection with 0.2ml of a 1:100 dilution of cedar. She recovered one hour later. Case 3 was a 22 year old female. She presented with an anaphylactic reaction, in addition to cough and itching 30 minutes after the injection of 0.2ml of a 1:1000 dilution of cedar. Case 4 was a 25 year old male. He presented with only itching approximately two hours after the injection of 0.07ml of a 1:100 dilution of cedar. Symptoms ceased in two hours. Case 5 was a 34 year old female. She presented with urticaria and coughing ten minutes after the injection of 0.05ml of a 1:100 dilution of cedar. She went into anaphylactic shock after forty minutes. Epinephrine was used to treat her, and she recovered two hours later. Case 6 was a 34 year old female. She had an anaphylactic reaction fifteen minutes after the injection of 0.5ml of a 1:10, 000 dilution of cedar.
Subsequent questioning of the female cases revealed that the systemic reaction occurred two or three days before menstruation. Increased osmolarity, electrolyte disturbances and altered transcapillary fluid balance were reported in association with premenstrual syndrome.
Following the last case, we avoided immunotherapy during the one to three day period before menstruation in female patients. Since then, we have experienced no case of systemic reaction out of ninety-six additional cases treated using immunotherapy after the intervening thirteen year period (from 1985 to 1998).
We concluded that the systemic reactions of female were related to premenstrual conditions.抄録全体を表示PDF形式でダウンロード (943K) -
中野 宏, 柴田 敏章, 中井 茂, 福島 龍之, 河田 了, 内田 真哉1999 年 92 巻 4 号 p. 375-379
発行日: 1999/04/01
公開日: 2011/11/04
ジャーナル フリーA case of mucoepidermoid carcinoma arising in the inferior surface of the tongue is described. A 78-year-old woman visited our hospital complaining of a tongue tumor and there was an associated lymph node swelling in the middle jugular chain. An incisional biopsy was performed, and was followed by a partial glossectomy and right-sided radical neck dissection. Pathological diagnosis of the tongue tumor was a low grade mucoepidermoid carcinoma with some lymph node metastasis. Since the prognosis of mucoepidermoid carcinoma differs considerably with grading, it was important to perform therapy in accordance with the grading. In this case, although the pathological diagnosis was low grade, it was thought to be high grade because of cervical lymph nodes metastasis. So we performed radical neck dissection for cervical metastasis and post operative radiotherapy.抄録全体を表示PDF形式でダウンロード (6050K) -
吉田 智子, 熊澤 博文, 白石 由里, 井上 俊哉, 岩井 大, 蔦 佳尚, 山下 敏夫, 坂井 田紀子1999 年 92 巻 4 号 p. 381-386
発行日: 1999/04/01
公開日: 2011/11/04
ジャーナル フリーWe investigated five patients with eosinophilic granulomas of soft tissue in the parotid region. Four patients were male and one patient was female. Patient age ranged from 11 to 42. The patients had moderate to marked eosinophilia in the peripheral blood and high serum immunoglobulin IgE. The lesions of Kimura's disease showed intermediate intensity on T1-weighted MRI and high intensity on T2-weighted images. Four patients were treated with surgical excision of the swollen parts of the facial tumor and received various medication therapies post operatively. One patient was treated with medication therapies alone, without surgical excision. Three patients who underwent full surgical excision recovered without recurrence. The remaining two patients have had repeated recurrences. A combination of surgery and medication is usually effective. However, when combination therapy is not effective, radiation therapy may be an alternative to prevent recurrence of Kimura's disease.抄録全体を表示PDF形式でダウンロード (6264K) -
―免疫組織化学法を用いて―高橋 英二, 小川 徹也, 伊藤 八次, 鈴木 智雄, 宮田 英雄1999 年 92 巻 4 号 p. 387-392
発行日: 1999/04/01
公開日: 2011/11/04
ジャーナル フリーThe development and progression of cancer are known to be regulated by various oncogenes and tumor suppressor genes. We investigated the expression of p53 and RB proteins in 13 cases of parotid carcinomas, which cases were admitted to the Department of Otorhinolaryngology, Gifu University School of Medicine from January 1989 to September 1998. These cases were investigated by immunohistochemical techniques using p53 and RB monoclonal antibodies. The results were as follows:
1) p53 protein nuclear staining was shown in 8 of 13 cases. A significant difference in the expression of p53 proteins was observed between high grade carcinoma groups and low grade carcinoma groups (Fisher's exact test; p=0.03). These results suggest that expression of p53 protein is related to the malignant grade of parotid gland carcinomas.
2) RB protein nuclear staining was shown in 7 of 13 cases. A significant difference in the expression of RB protein was not observed between high grade carcinoma groups and low grade carcinoma groups (Fisher's exact test; p=0.27). Expression of RB protein did not appear to be related to malignant grade of parotid gland carcinomas.抄録全体を表示PDF形式でダウンロード (4916K) -
渡辺 哲生, 末永 智, 須 小毅, 鈴木 正志, 茂木 五郎1999 年 92 巻 4 号 p. 393-400
発行日: 1999/04/01
公開日: 2011/11/04
ジャーナル フリーWe present 6 patients with a retropharyngeal abscess who were treated at our hospital as well as a review of the subject in the Japanese literature over the past 30 years. The incidence of retropharyngeal abscess among patients in our hospital was about 5% among patients with deep neck infections. Five of the 6 patients were adults. The causes of the abscess were foreign bodies in 2 patients, and acute infection of the upper respiratory tract, trauma, pyogenic cervical spondylosis and endoscopy respectively, in each of the other patients. Two patients had diabetes mellitus. Surgical drainage was performed via an intraoral approach in 3 patients and an extraoral approach in 3. A tracheotomy was necessary in 11 patient. Review of the Japanese literature showed an increased incidence of abscesses in adult patients with acute upper respiratory tract infection or diabetes, a pattern that paralleled that in our experience. The number of patients with fatal complications like mediastinitis increased over the 30-year period. Although retropharyngeal abscess is relatively rare, an understanding of this disease and appropriate treatment are required.抄録全体を表示PDF形式でダウンロード (5409K) -
新井 信一郎, 澤井 薫夫, 藤井 恵子, 秋田 茂樹, 水田 啓介, 鈴木 智雄, 宮田 英雄1999 年 92 巻 4 号 p. 401-406
発行日: 1999/04/01
公開日: 2011/11/04
ジャーナル フリーThe case of bilateral parapharyngeal abscesses in a 61 year-old man is reported. This patient had complaints of a sore throat and swelling on his anterior left ear. We diagnosed bilateral parapharyngeal abscesses on CT and MRI scans.
A bacteriological study of these abscesses revealed both aerobic and anaerobic bacteria; a mixed infection of streptococcus constellatus and prevotella intermedia had caused serious inflammation. Drainage and antibiotic therapy proved to be effective.抄録全体を表示PDF形式でダウンロード (3410K) -
雨皿 亮, 鈴村 恵理1999 年 92 巻 4 号 p. 407-411
発行日: 1999/04/01
公開日: 2011/11/04
ジャーナル フリーA rare case of solitary extramedullary plasmacytoma of the thyroid gland which occurred in a 44 year-old female is reported. The patient visited us complaining of a painless anterior cervical mass. CT findings revealed a 2×2cm low density mass with strong enhancement. Aspiration cytology results were class II. Right hemithyroidectomy and regional neck dissection were performed. Postoperative histological examination revealed that the tumor was an IgG-kappa producing plasmacytoma accompanied by chronic thyroiditis. There was no evidence of lymphnodal metastasis or distant metastasis. Neither M-protein in the serum nor Bence Jones protein in the urine was detected.抄録全体を表示PDF形式でダウンロード (5491K) -
朝倉 光司, 氷見 徹夫, 原渕 保明, 浜本 誠, 形浦 昭克, 晴山 雅人, 傳野 隆一, 平田 公一, 草島 勝之1999 年 92 巻 4 号 p. 413-417
発行日: 1999/04/01
公開日: 2011/11/04
ジャーナル フリーA clinical study was performed on 25 patients with cervical esophageal carcinomas who had been treated at the Sapporo Medical University from 1983 to 1995.
The disease-specific 5-year cumulative survival rate was 34.2% overalls and 41.2% in the radical surgery cases. There were no long-term survivors in the radiotherapy cases. Tumor control was better in those cases receiving blunt dissection of the total esophagus than in those receiving a cervical dissection; the 5-year cumulative survival rate of the former group was 51.6%. Recurrence of the disease in the cervical lymph nodes was not noted in the cases receiving a radical neck dissection.抄録全体を表示PDF形式でダウンロード (682K) -
小宮 尚, 山川 卓也, 岡添 真介, 片岡 丈志, 川野 健二1999 年 92 巻 4 号 p. 419-423
発行日: 1999/04/01
公開日: 2011/11/04
ジャーナル フリーA case of spontaneous mediastinal emphysema is reported. A 14-year-old boy presented with a sore thoat and pains in the neck and anterior chest. The symptoms appeared after he drank soda water. Plain x-ray and a CT scan of the neck and mediastinum revealed air around his trachea and in the soft tissue of his neck. These symptoms were reduced by antibiotic therapy and bed rest. This patient was thought to represent a case of spontaneous mediastinal emphysema.抄録全体を表示PDF形式でダウンロード (4442K) -
青野 央1999 年 92 巻 4 号 p. 425-433
発行日: 1999/04/01
公開日: 2011/11/04
ジャーナル フリーElectrical stimulation of the affected muscle is one therapeutic scheme for treatment of severe facial palsy, although the efficacy of electrical stimulation has not been clearly demonstrated. The purpose of this study was to determine if and how electrical stimulation of the mimetic muscle influences muscle atrophy and regeneration of the innervating nerve in the course of facial paralysis. Facial palsy was induced in guinea pigs by clamping the bilateral facial nerves for 15 minutes. Repeated electric stimulation of 0.1ms in duration (20Hz) and 10V in strength, for 20 minutes a day, was administered to the orbicularis oculi muscle of the left side. Electrical stimulation was administered in the three ways; daily for 20 days during the whole course of facial palsy (group A), daily for days 1-10 after paralysis (group B) and daily for days 11-20 (group C). Electromyographical and histochemical findings showed that the muscle atrophy was prevented in all groups irrespective of the timing of electrical stimulation, however, nerve regeneration was inhibited in groups A and C. These results suggest that electrical stimulation of the muscle should not be conducted after the 10th day of palsy when the innervating nerve has reached the affected muscle.抄録全体を表示PDF形式でダウンロード (5725K) -
―スギ花粉症に対するDSCGとの比較―荻野 敏, 入船 盛弘, 仙波 治, 坂口 喜清, 馬谷 克則, 野入 輝久, 榎本 雅夫, 寒川 高男, 北嶋 和智1999 年 92 巻 4 号 p. 435-450
発行日: 1999/04/01
公開日: 2011/11/04
ジャーナル フリーThe clinical usefulness of 200μg/day of mometasone furoate (MF) nasal spray administered over 2 weeks was compared against 31.2μg/day of disodium cromoglycate (DSCG) using a telephone nominating method in a total of 69 patients with Japanese cedar pollenosis.
The Japanese cedar pollen count in 1996 was extremely low, apporoximately 1/10-4/20 of that in 1995. On an analysis of the overall improvement, marked or moderate improvement was observed in 69.0% (20/29) and 20.7% (6/29) of patients receiving MF and DSCG, respectively; this was statistically different. MF also showed significantly superior efficacy over DSCG in almost all subjective and objective nasal symptoms. A significant correlation between the total nasal symptom scores based on three main symptoms of nasal allergy and overall improvement judged by an independent investigator was confirmed. The proper discriminant rate by discriminant analysis was high at 93.1%. On an analysis of the overall safety, good safety was observed for both treatment groups. The above results suggest that MF is highly useful in the treatment of Japanese cedar pollenosis.抄録全体を表示PDF形式でダウンロード (1981K) -
臼井 信郎1999 年 92 巻 4 号 p. 452-453
発行日: 1999/04/01
公開日: 2011/11/04
ジャーナル フリーPDF形式でダウンロード (300K)
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