Practica Oto-Rhino-Laryngologica
Online ISSN : 1884-4545
Print ISSN : 0032-6313
ISSN-L : 0032-6313
Volume 94, Issue 11
Displaying 1-17 of 17 articles from this issue
  • Tamotsu HATADA
    2001 Volume 94 Issue 11 Pages 957-962
    Published: November 01, 2001
    Released on J-STAGE: November 04, 2011
    JOURNAL FREE ACCESS
    The etiology in most inner ear diseases remains to be clarified and although immunologic injury was implicated in the pathogenesis of inner ear diseases in McCabe's report, “Auto Immune Sensorineural Hearing Loss”, an autoimmune etiology could not be proven because the inner ear is an extremely small sensory organ. Recently, advances in the cellular and molecular analysis of immunological reactivity have been increasingly applied to diseases of the inner ear, and in this chapter, the author first describes some animal models of immune mediated inner ear diseases, followed by discussion of clinical studies. The immunological study of immune mediated inner ear diseases ofen requires readily available purified inner ear antigen. Some authors have reported that the fractionations (32-35, 42, 68 kDa) of the inner ear proteins from the inner ear tissue were important in immune mediated inner ear diseases, however, these proteins are widely distributed and not specific to the inner ear. Further purification of the antigens from the corresponding inner ear locations and the study of their amino acid and DNA sequences, in order to synthesize inner ear antigens for use in clinical investigation into inner ear diseases, may be possible in the future.
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  • [in Japanese], [in Japanese]
    2001 Volume 94 Issue 11 Pages 964-965
    Published: November 01, 2001
    Released on J-STAGE: November 04, 2011
    JOURNAL FREE ACCESS
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  • Masakatsu TAKI, Hirofumi SAKAGUCHI, Masataka MURAKAMI, Yasuo HISA, Fum ...
    2001 Volume 94 Issue 11 Pages 967-972
    Published: November 01, 2001
    Released on J-STAGE: November 04, 2011
    JOURNAL FREE ACCESS
    Dolichoectasia often causes neurological symptoms, because it presses on cranial nerves and the brain stem. We report a case of dolichoectasia of the vertebral artery. The patient was a 66-year-old woman with hypertension and diabetes mellitus, who presented with dizziness. MRI and MRA revealed compression of the brain stem by elongation of the right vertebral artery. An otoneurological examination was performed and the results of OKP and ETT suggested dysfunction of the middle cerebellar peduncle in the same position as suggested by MRI and MRA.
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  • -Trial of Glycerol Infusion Therapy-
    Yoshihiro OHNO, Masayuki TOMIFUJI
    2001 Volume 94 Issue 11 Pages 973-977
    Published: November 01, 2001
    Released on J-STAGE: November 04, 2011
    JOURNAL FREE ACCESS
    The prognosis of acute low-tone sensorineural hearing loss (ALHL) is generally favorable, but partial cases show poor improvements or recurrences. In the present study, we investigated the clinical efficacy of continuous intravenous infusion of glycerol as a treatment of ALHL since endolymphatic hydrops is known to be one of the pathogenesis of ALHL.
    Two hundred to three hundred milliliters of glycerol were administered to three patients with ALHL to investigate the clinical efficacy of the product. Although these patients had been treated with other drugs such as steroids and isosorbide, hearing loss was not completely alleviated. However, after treatment with glycerol the auditory functions of these patients were improved, particularly the low-tone ranges. No adverse effects such as nausea or headache, which are usually caused by the oral administrations of glycerol, were manifested in these patients.
    Based on the findings in this study, we suggest that endolymphatic hydrops is involved in the manifestation of ALHL, and that glycerol is one of the appropriate agents for patients who are resistant to other pharmacological interventions.
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  • Masakazu HANAMITSU, Mikio SUZUKI, Hiroya KITANO, Tomio OGAWA, Hisaya N ...
    2001 Volume 94 Issue 11 Pages 979-982
    Published: November 01, 2001
    Released on J-STAGE: November 04, 2011
    JOURNAL FREE ACCESS
    Pulsatile tinnitus or cardiac synchronous sound is a rare symptom, but it is often due to an intracranial vascular lesion. We report two patients with pulsatile tinnitus, one was objective, in that it was detected by the examiner, with a dural arteriovenous fistula and the other was subjective, in that it was heard only by the patient, with a constriction or obstruction of the posterior cerebral artery. These lesions were detected by MR angiography. MR angiography is less invasive compared with selective X-ray angiography, and may be useful for the screening examination of pulsatile tinnitus.
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  • Kazuhiko NARIO, Hiroshi MIYAHARA, Takashi UEDA, Takashi MATSUNAGA
    2001 Volume 94 Issue 11 Pages 983-990
    Published: November 01, 2001
    Released on J-STAGE: November 04, 2011
    JOURNAL FREE ACCESS
    We report a case of glomus tympanicum tumor in a 27-year old female who presented with right hearing loss, fullness of ear and pulsatile tinnitus. Otoscopic examination revealed a reddish mass in the tympanic cavity through the tympanic membrane. CT scans and MR images revealed that the tumor was localized in the mesotympanium without bone destruction. Angiographic findings revealed that the tumor feeding artery was the ascending pharyngeal artery. The tumor was completely resected via a transmeatal approach after embolization of the ascending pharyngeal artery. Postoperatively tinnitus and fullness of ear disappeared. No recurrence was confirmed 3 years after surgery. We reviewed 38 cases including this case of glomus tympanic tumor previously reported in Japan. Preoperative embolization was very useful to control blood loss intraoperatively.
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  • Soichi YAMAGUCHI, Yugo NOGUCHI, Akinori KIDA
    2001 Volume 94 Issue 11 Pages 991-995
    Published: November 01, 2001
    Released on J-STAGE: November 04, 2011
    JOURNAL FREE ACCESS
    Ameloblastoma is one of the most common odontogenic tumors and it appears frequently in the mandible but rarely in the maxilla. We report a case of ameloblastoma of the maxilla in a 19-year-old woman in whom a partial maxillary resection was performed in July 1999.
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  • Masayuki MINAMINO, Hiroyuki TSUJI, Masao YAGI, Toshio YAMASHITA, Norik ...
    2001 Volume 94 Issue 11 Pages 997-1000
    Published: November 01, 2001
    Released on J-STAGE: November 04, 2011
    JOURNAL FREE ACCESS
    The patient was a 48 year-old female who presented with soft palate swelling. On examination a painless mass with no nerve involvement was detected. Examination of the neck showed a 5cm node located in the parapharyngeal space. The tumor was resected transcervically via a visor flap. Histologically the tumor was diagnosed as malignant based on pleomorphic adenoma. Malignant pleomorphic adenoma arising in the parapharyngeal space from the minor salivary gland is very rare.
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  • Kyoichi TERAO, Masahiro ISHIKAWA, Yukio Tanaka, Takeshi KUSUNOKI, Kazu ...
    2001 Volume 94 Issue 11 Pages 1001-1005
    Published: November 01, 2001
    Released on J-STAGE: November 04, 2011
    JOURNAL FREE ACCESS
    We encountered a rare case of malignant lymphoma from the postcricoid area of the hypopharynx in a 69-year-old female. The patient presented with a six week history of throat pain and on examination a smooth and well-defined mass was found in the right postcricoid area of the hypopharynx. The mass was about 2cm in size, pale pink and partially red. Enhanced CT and MRI (Gd) revealed partial enhancement and a slightly irregular, homogenous mass 2cm in size in the right postcricoid area. Ga67 scintigraphy revealed uptake only by the hypopharyngeal tumor lesion. The mass was biopsied with laryngofiberscopy and the pathological diagnosis was non-Hodgkin's lymphoma, diffuse large B cell type. After the I E Ann Arbor clinical stage was established, radiation therapy alone was begun. There has been no evidence of recurrence for 1 year 8 months after primary therapy. Radiation therapy alone was selected because the tumor was regional type stage IE and was small and could be effectively treated with primary therapy. However, since it was classified as intermediate grade in Working Formulation, careful follow up is necessary.
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  • Koji MIYATA, Ken-ichi KANEKO, Ryo ASATO, Tomoya NAGATA, Masamitsu YAMA ...
    2001 Volume 94 Issue 11 Pages 1007-1011
    Published: November 01, 2001
    Released on J-STAGE: November 04, 2011
    JOURNAL FREE ACCESS
    We report here two cases of laryngitis due to varicella-zoster virus infection. The patients were a 68-year-old male and a 37-year-old male who both presented with pharyngeal pain. A white erosive lesion was noted on hemilateral side of the larynx, but no vocal cord paralysis was observed in either patient. Based on the unilaterality of the lesion, we made a diagnosis of herpes zoster of the larynx. Laryngitis was successfully treated using the administration of acyclovir. Histopathological examination suggested inflammation due to virus, and DNA in situ hybridization revealed varicella-zoster virus.
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  • Michiya KOSAKA, Yasutaka HORI, Yoko HAGIIKE, Hirofumi AKAGI
    2001 Volume 94 Issue 11 Pages 1013-1017
    Published: November 01, 2001
    Released on J-STAGE: November 04, 2011
    JOURNAL FREE ACCESS
    We report a case of giant pleomorphic adenoma of parotid gland. The patient was a 66-year-old female who first noticed the mass 30 years previously, although the mass had not been treated. The tumor gradually enlarged and on examination at our hospital on March the third 1999, the tumor was 13×11×9cm. The patient underwent total parotidectomy and since the tumor involved a facial nerve, the nerve was resected and we grafted the cervical sensory plexus. Midline mandibulotomy was performed because the tumor extended to the parapharyngeal space. Histopathologically, there was no evidence of malignancy. Facial palsy was gradually improved postoperatively and there has been no recurrence for two years.
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  • Shingo KAKIMOTO, Masayuki FURUKAWA, Hisaya YUKAWA, Shinryu LEE, Toshio ...
    2001 Volume 94 Issue 11 Pages 1019-1023
    Published: November 01, 2001
    Released on J-STAGE: November 04, 2011
    JOURNAL FREE ACCESS
    Generally, the prognosis of thyroid anaplastic carcinoma is extremely unsatisfactory. We report here excellent results due to early treatment in a patient with anaplastic carcinoma. The patient was a 74-year-old female, who presented with an enlarged frontal neck tumor, together with cervix and throat pain, and undifferentiated carcinoma was strongly suspected based on aspiration biopsy cytology. The patient was admitted and six days after the first examination, total thyroidectomy was performed, and a diagnosis of anaplastic thyroid carcinoma was made based on the permanent pathological specimen. Postoperatively, EAP (Etoposide, Adriamycin, and Cisplatin) treatment and radiotherapy (56 Gy) were performed, with a subsequent second chemotherapy course. At two years no recurrence or metastasis has been noted and the patient has returned to her normal daily life. In conclusion, if radical dissection of the tumor is possible in the early stages, we consider that in patients with anaplastic thyroid carcinoma immediate operation and radiation and chemotherapy treatment should result in a positive prognosis.
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  • Masayuki SAKAMOTO, Norifumi INOUE
    2001 Volume 94 Issue 11 Pages 1025-1028
    Published: November 01, 2001
    Released on J-STAGE: November 04, 2011
    JOURNAL FREE ACCESS
    The patient was a 58-year-old male who had undergone right nephrectomy one and a half years previously for right renal cell cancer was examined for repeated epistaxis from the right nasal cavity. Using a nasoscope, a tumor was noted in the right middle nasal tubinate. Histopathological study revealed metastatic renal cell carcinoma. The tumor was resected endoscopically and epistaxis did not recur in the right nostril but about one year after the initial surgery, epistaxis occurred in the left nasal cavity. A second tumor was found in the left middle nasal meatus and since the general condition of the patient was too poor for a radical operation, radiotherapy was performed. Although epistaxis stopped after radiotherapy was started, the patient died of the disease with respiratory failure two months later.
    In this report, we also discuss the appropriate therapy for metastatic renal cell carcinoma in the nasal cavity from the standpoint of the patient's quality of life.
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  • Shin-ichiro KITAJIRI, Harukazu HIRAUMI, Tomoko HIROSE
    2001 Volume 94 Issue 11 Pages 1029-1032
    Published: November 01, 2001
    Released on J-STAGE: November 04, 2011
    JOURNAL FREE ACCESS
    We report two cases of spontaneous mediastinal emphysema. A 34-year-old male (case 1) and 16-year-old male (case 2) developed pain in their necks and chests after shouting (case 1) and playing football (case 2). Neck and chest CT revealed mediastinal emphysema. Both patients were treated with bed rest and antibiotic therapy, and recovered completely within three days.
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  • Naoki HYAKUSHIMA, Hiroshi TSUBOTA, Hiroaki MITSUZAWA, Tetsuo HIMI
    2001 Volume 94 Issue 11 Pages 1033-1037
    Published: November 01, 2001
    Released on J-STAGE: December 12, 2011
    JOURNAL FREE ACCESS
    We report a case of Lemierre's syndrome, known as postanginal sepsis, which resulted in internal jugular vein thrombosis with septic pulmonary embolism.
    A 53-year-old man was admitted with sore throat, fever, and left-sided neck pain and swelling. He had no chest pain and no dyspnea. Contrast enhanced CT scan of the neck revealed swelling of the left tonsil without abscess formation and low-density lumen with peripheral enhancement of the wall of the left internal jugular vein. Chest CT scan showed multiple round nodules with cavitation indicating the typical appearance of septic pulmonary embolism. There was no definite pleural effusion. Streptococcus intermedius was found on blood cultures. Based on the findings we diagnosed left internal jugular vein thrombosis with septic pulmonary embolism due to acute tonsillitis, and administration of intravenous antibiotics and heparin was started. Fever subsided by hospital day 7, and the neck swelling and tenderness gradually reduced. Three months later, pulmonary nodules disappeared; however no blood flow of the internal jugular vein was noted, suggesting organization of the thrombus in the vein.
    The treatment of internal jugular vein thrombosis is also discussed.
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  • Takeshi Tanaka, Koji IWAI, Masaharu SUDO, Hitoshi Saito
    2001 Volume 94 Issue 11 Pages 1039-1044
    Published: November 01, 2001
    Released on J-STAGE: November 04, 2011
    JOURNAL FREE ACCESS
    We report two cases of thyroid hemiagenesis. The first case was a 49-year-old female with hemiagenesis of the left thyroid lobe and the second case was 75-year-old female with goiter in the right thyroid lobe and a defect of the left lobe. In both patients the thyroid function tests were euthyroid, and US, CT and 99mTcO4-scintigraphy were useful for the diagnosis of thyriod hemiagenesis Both patients are being conservatively managed without surgery.
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  • [in Japanese]
    2001 Volume 94 Issue 11 Pages 1046-1047
    Published: November 01, 2001
    Released on J-STAGE: November 04, 2011
    JOURNAL FREE ACCESS
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