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97 巻, 12 号
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北原 糺, 久保 武2004 年 97 巻 12 号 p. 1029-1039
発行日: 2004/12/01
公開日: 2011/10/07
ジャーナル フリーTransient receptor potential cation channel subfamily V (TRPV) is a non-specific cation ion channel receptor family with six transmembrane domains. At first, TRPV1 was cloned in 1997 as a nociceptive receptor sensitive to capsaicin, an essence of hot chili pepper. So far, it has been revealed to be responsive to various kinds of nociceptive stimuli such as, heat, proton ion, low extracellular osmolarity and so on. That's why we, neuro-otologists, are quite interested in roles of this family in the inner ear. It might be possible that TRPV family in the inner ear is involved in the mechanism of caloric-induced nystagmus, the way of bicarbonate action against vertigo and the pathogenesis of endolymphatic hydrops syndrome including Meniere's disease. Here, we would like to review recent findings about TRPV family together with our data and suggest new insights for breaking through unsolved questions in neuro-otology.抄録全体を表示PDF形式でダウンロード (8409K) -
竹内 健二, 旭 宏, 吉岡 哲志, 内藤 健晴2004 年 97 巻 12 号 p. 1040-1041
発行日: 2004/12/01
公開日: 2011/10/07
ジャーナル フリーPDF形式でダウンロード (2076K) -
松田 秀樹, 吉田 高史, 堀内 長一, 佐野 大佑, 佃 守2004 年 97 巻 12 号 p. 1043-1047
発行日: 2004/12/01
公開日: 2011/10/07
ジャーナル フリーA 22-year-old female, who had been diagnosed with aortitis syndrome five years earlier, consulted our clinic in May 1992 complaining of hearing loss and tinnitus in the right ear. Since the first onset of hearing loss, pure-tone audiogram was performed many times over a period of twelve years. Hearing fluctuated with no relation to the dose of steroid hormone during the initial three years, but hearing improvement thereafter depended on the dose of steroid hormone. During long-term follow-up, hearing disturbance gradually progressed. A tendency for CRP to become elevated and the sedimentation rate to increase just before hearing worsened was found. It appeared that hearing loss was one of the symptoms of aortitis syndrome. Cases of sensorineural hearing loss with aortitis syndrome should be followed for a long time, because in some cases previously reported hearing disturbance progresses.抄録全体を表示PDF形式でダウンロード (2072K) -
大西 和歌, 根来 篤, 辻 恒治郎, 武藤 俊彦, 野崎 隆平, 阪上 雅史2004 年 97 巻 12 号 p. 1049-1052
発行日: 2004/12/01
公開日: 2011/10/07
ジャーナル フリーTinnitus which others can hear is rare. We experienced a case of a 32-year-old woman with objective tinnitus which could be detected voluntarily. Periodic tinnitus of a non-cardiac pulsation nature was audible from the left ear by otoscopy. Synchronized with the tinnitus, the contraction around the left pharyngeal opening of the Eustachian tube was observed by fiberscopy. The results of audiometry, impedance audiometry and CT were normal. Furthermore, scince there was no soft palate movement, the diagnosis of tinnitus by myoclonus of the tensor veli palatini muscle was made. Medication was not effective in this case.抄録全体を表示PDF形式でダウンロード (5472K) -
平海 晴一, 三浦 誠, 廣瀬 知子2004 年 97 巻 12 号 p. 1053-1058
発行日: 2004/12/01
公開日: 2011/10/07
ジャーナル フリーThree cases of central positional vertigo (central PV) in young patients were reported. The first case had combined torsional and horizontal nystagmus to the right in a head-hanging position. The nystagmus lacked latency and did not diminish easily. Magnetic resonance imaging (MRI) scan showed a tumor in the medulla, which was histologically diagnosed as astrocytoma. The second case had very weak apogeotropic nystagmus with torsional and horizontal components in a head-hanging-left position. The nystagmus diminished after 3 or 4 beats, but was easily reproduced. MRI showed arteriovenous malformation in the vermis. The third case showed positional nystagmus that resembled benign paroxysmal positional vertigo (BPPV), but did not respond to vestibular rehabilitation therapy. MRI showed multiple tumors in the cerebellum, which were histologically diagnosed as neuroblastoma. Close examination of nystagmus based on an understanding of BPPV is the most useful clue for a correct diagnosis. However, even if the nystagmus is consistent with that of BPPV on initial assessment, central PV cannot be excluded, and careful follow-up is necessary until both objective and subjective symptoms diminish.抄録全体を表示PDF形式でダウンロード (7342K) -
西池 季隆, 長井 美樹, 中川 あや, 小西 雅樹, 坂田 義治, 大木 孝一2004 年 97 巻 12 号 p. 1059-1066
発行日: 2004/12/01
公開日: 2011/10/07
ジャーナル フリーWe experienced two cases of ossicular lesions in which three-dimensional (3D) images from multislice CT (MSCT) were useful in diagnosing the lesions. In the first case, the 3D images revealed an ossicular defect in the long process of the incus and the superstructure of the stapes in the middle ear. In the second case, discontinuity of the incudostapedial joint was revealed. The hearing level in both cases was improved by tympanoplasty. In the first case, besides the ossicular malformation, open-type congenital cholesteatoma was found in the middle ear during the operation. There is a possibility of residual recurrence of open-type cholesteatoma, so postoperative follow-up was necessary for the first case. Canal wall up tympanoplasty with posterior hypotympanotomy was performed in the second case. Since this procedure does not require managing the external auditory meatus or the tympanic membrane, it should be chosen in cases of normal tympanic membrane with traumatic ossicular chain discontinuity, such as the second case. In conclusion, reconstruction of 3D images by MSCT with 8 rows of detectors gave realistic and high-quality images of the ossicular lesions. The 3D images were useful for the surgeon's preoperative planning and for the patient's informed consent to the operation.抄録全体を表示PDF形式でダウンロード (9178K) -
山口 太郎, 鈴木 衛, 河野 淳, 湯川 久美子, 飯村 陽一, 藤田 博之2004 年 97 巻 12 号 p. 1067-1070
発行日: 2004/12/01
公開日: 2011/10/07
ジャーナル フリーWe performed surgery of the middle ear in 157 patients (171 ears) between April 1997 and March 2001. In this study, the clinical features and outcomes of middle ear surgery performed in 11 patients (13 ears) 70 or more years of age were analyzed. The diagnoses in these 11 cases included chronic otitis media (6 ears), otitis media cholesteatoma (6 ears), and otosclerosis (1 ear). The types of surgery were myringoplasty (2 ears); tympanoplasty type I (3 ears), type IIIc (6 ears) and type IVc (1 ear); tympanoplasty without ossiculoplasty (1 ear); and stapes surgery (1 ear). Surgery was successful in improving the hearing in 4 ears. Prevention of discharge was the primary purpose of surgery in 10 ears, and discharge was controlled in 9 ears. There were no complications or adverse events associated with the surgery. Surgery can be selected to improve the QOL of patients even if marked improvement in hearing is not expected.抄録全体を表示PDF形式でダウンロード (495K) -
泉 智沙子, 岩崎 聡, 名倉 三津佳, 渡邉 高弘, 武林 悟, 水田 邦博, 峯田 周幸2004 年 97 巻 12 号 p. 1071-1074
発行日: 2004/12/01
公開日: 2011/10/07
ジャーナル フリーOctylcyanoacrylate is a tissue adhesive that has been approved for closure of surgical incisions. Since 2002 to 2003, we have used this tissue adhesive (marketed as DERMABOND®) for skin closure following cochlear implant surgery in 16 adults and 16 children. Infants aged 2-3 years old comprised 37.5% of the patients. The post-auricle incision was J-shaped, the wound was 6cm in length, and there were no major problems of wound dehiscence or infection. Minor problems arose in 5 patients (15.6%), including partial dehiscence in two patients, partial infection in two patients and partial post-auricle edema in one patient, but all of these resolved spontaneously. A drainage tube was inserted into the wound in five patients, but there were no problems in these cases. Using an octylcyanoacrylate tissue adhesive has many advantages. It eliminates the need for suture removal and disinfection, and allows wounds to get wet briefly during showering or bathing, because a barrier function against microbial penetration or moisture is present. This is especially advantageous in young patients. Our current experience with this approach demonstrates that DERMABOND® can be used successfully and appropriately for wound closure after a variety of ear surgeries.抄録全体を表示PDF形式でダウンロード (3061K) -
増田 行広, 田部 哲也, 大前 由紀雄, 村田 保博, 小倉 雅實, 前川 仁, 村川 哲也, 北原 哲2004 年 97 巻 12 号 p. 1075-1081
発行日: 2004/12/01
公開日: 2011/10/07
ジャーナル フリーHereditary hemorrhagic telangiectasia (HHT), labeled Osler-Weber-Rendu Disease, is a systemic autosomal dominant disorder involving blood vessels, and is characterized by a triad of features including telangiectasia, recurrent epistaxis, and positive family history. Over the last 100 years since the disease was first described, no therapy has completely resolved the epistaxis. However, for reducing the frequency of the epistaxis and bleeding time, several treatments for the epistaxis have been reported. Since the early 1980s, laser therapy has been considered a useful method for patients with HHT because the laser can be used to specifically target tissues and vasculature, depending on the absorbance and transmittance of the tissues. Although various lasers have been evaluated, the potassium-titanyl-phosphate (KTP) laser is relatively rare. We present the case of a 64-year-old woman with HHT who underwent the KTP laser procedure in an out-patient setting. She had telangiectasia of the tongue, lip, skin, and intranasal membrane. She also had recurrent epistaxis and positive family history, which resulted in a diagnosis of HHT. The technique uses a low-power setting of approximately 0.5 to 2.0 watts with continuous wave. She underwent the procedure 8 times. The technique using the KTP laser for photocoagulation of intranasal telangiectases, and some considerations about epistaxis with HHT are presented. This technique resulted in reduction of the frequency of epistaxis, a decrease in the bleeding time, and improvement of the quality of life for this patient. We suggest that KTP laser therapy is a successful method for controlling epistaxis in patients with HHT.抄録全体を表示PDF形式でダウンロード (5687K) -
瀬野 悟史, 鈴木 幹男, 花満 雅一, 桜井 弘徳, 那須 準子, 北西 剛, 清水 猛史2004 年 97 巻 12 号 p. 1083-1087
発行日: 2004/12/01
公開日: 2011/10/07
ジャーナル フリーAn inflammatory pseudotumor is one of the major neoplasm arising in the orbit. We reported a case of inflammatory pseudotumor of the orbit that was successfully treated. A 73-old-male was referred to our department with a complaint of swelling of the left eye lid. CT findings showed a tumor of the left orbit extending into the ethmoid sinus. Incisional biopsy was performed through the left maxillary sinus. Histologic examination demonstrated a non-specific inflammatory lesion with fibrous tissues and inflammatory cells. The pathologic diagnosis was benign pseudotumor. The patient was given steroid therapy (for 5 weeks) and radiotherapy (2Gy×10 days) which resulted in complete response at discharge. Steroid therapy was continued for 6 months after discharge. There has not been any recurrence of the tumor during more than 2 years follow up. Clinical manifestations, histopathologic findings and treatment of this lesion are discussed.抄録全体を表示PDF形式でダウンロード (4950K) -
小坂 道也, 大上 哲生, 谷本 一憲, 折田 左枝子, 折田 頼尚, 前田 学, 西崎 和則2004 年 97 巻 12 号 p. 1089-1094
発行日: 2004/12/01
公開日: 2011/10/07
ジャーナル フリーIn Japan, most commonly used incision for parotidectomies is an S-shaped incision. The major problem with this incision is the visible scar in the preauricular and cervical area. To obtain more cosmetic approach to parotid surgery, Appiani suggested in 1967 that a facelift incision (rhytidectomy incision) be used to expose the parotid gland. We employed this incision for a motivated patient who was suspected of having a benign tumor. Eleven parotidectomies using this incision were performed between 1 January 2001 and 1 April 2004, in 10 females and 1 male, ranging in age from 23 to 62 years old (mean 39.6 years old). The pathology was pleomorphic adenoma in all cases. The duration of surgery ranged from 1.98 hours to 3.25 hours (mean 2.48 hours). In all cases, excellent exposure could be achieved through this approach, and the facial nerves were preserved. There were no remarkable complications. In conclusion, the facelift incision can provide adequate surgical exposure and good cosmetic results in patients with parotid tumor.抄録全体を表示PDF形式でダウンロード (9860K) -
井岡 宣人, 任 書晃, 中江 進2004 年 97 巻 12 号 p. 1095-1100
発行日: 2004/12/01
公開日: 2011/10/07
ジャーナル フリーWe report a case of oncocytomas arising from both side of parotid glands. The patient was a 47-year-old female complaining of left subaural pain. CT scanning and MRI showed one mass in the left parotid gland, and another mass in the right parotid gland. These tumors exhibited intense uptake and prolonged retention of Tc-99m pertechnetate. Surgical resection of both parotid tumors was performed. The histopathological diagnosis was oncocytoma in both parotid glands. Electron microscopic studies revealed an increased number of mitochondria.抄録全体を表示PDF形式でダウンロード (9313K) -
吉福 孝介, 福岩 達哉, 西元 謙吾, 松根 彰志, 黒野 祐一2004 年 97 巻 12 号 p. 1101-1106
発行日: 2004/12/01
公開日: 2011/10/07
ジャーナル フリーA case of suspected laryngeal tuberculosis accompanied by lung tuberculosis was reported in this paper. The patient was a 72 year-old male. He had developed hoarseness, sore throat and pain on swallowing, and consulted our clinic. Laryngoscopic examination showed swelling of the left arytenoid as well as laryngeal palsy. Pulmonary tuberculosis was diagnosed by microbiological identification of tubercle bacillus in the sputum. Although there was no evidence indicating laryngeal tuberculosis, local areas in the larynx were markedly improved after treating the patient with anti-tuberculosis chemotherapy. Consequently the patient was diagnosed as having laryngeal tuberculosis. Laryngeal tuberculosis is now rare in Japan, but it was suggested that careful attention should still be paid to the differential diagnosis of laryngeal inflammatory diseases.抄録全体を表示PDF形式でダウンロード (7333K) -
稲岡 孝敏, 菊川 達雄, 河田 桂2004 年 97 巻 12 号 p. 1107-1111
発行日: 2004/12/01
公開日: 2011/10/07
ジャーナル フリーParathyroid adenomas sometimes cause nephrolithiases or bone disorders, but most cases pass subclinical courses and are found incidentally by routine blood tests. We report a case of parathyroid adenoma causing posterior mediastinal hemorrhage. The parathyroid adenoma was excised five months subsequent to the hemorrhage, after the hematoma had efficiently subsided, with no major bleeding. The postoperative course was uneventful with an expected decrease in serum calcium and intact PTH.抄録全体を表示PDF形式でダウンロード (7682K) -
稲川 俊太郎, 中山 明峰, 砂川 博, 佐藤 圭, 佐々木 弘和, 稲福 繁2004 年 97 巻 12 号 p. 1113-1118
発行日: 2004/12/01
公開日: 2011/10/07
ジャーナル フリーSixty percent of allergic rhinitis patients develop allergic conjunctivitis, especially patients diagnoised with cedar pollinosis. The method of treatment prescribed by otolaryngologists has been ZEPELIN® ophthalmic solution with results showing marked improvement.
1. Objective: To determine the treatment and follow-up care of patients with allergic conjunctivitis.
2. Patients: All patients were evaluated for itchiness of the eye before and after applying ZEPELIN® ophthalmic solution using the visual analogue scale (VAS)
3. Results: The average age of patients in the study was 46.2 years. Forty-one patients were given anti-allergy medicine and 24 patients were given a steroid nasal spray. Patients given ZEPELIN® ophthalmic solution showed marked improvement in allergic conjunctivits.
4. Conclusions: The ZEPELIN® ophthalmic solution is considered a safe and effective treatment of allergic conjunctivits for the otolaryngologist.抄録全体を表示PDF形式でダウンロード (657K) -
原渕 保明2004 年 97 巻 12 号 p. 1120-1121
発行日: 2004/12/01
公開日: 2011/10/07
ジャーナル フリーPDF形式でダウンロード (2962K)
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