We report here the progress of Arginine( Arg) treatment in a female hemodialysis patient with pressure ulcer or bed sore. As the patient had inferior granuloma growth in sacral ulcer, she was administered Arg-reinforced product. Administration of Abound
TM fortified with Arg and glutamine( Gln) promoted granuloma growth, but caused an excessive rise in BUN, 111 to 135 mg/dL. Administration of ISOCAL ® PLUS EX fortified only with Arg lowered BUN to 67 mg/dL. The result suggests that Gln is possibly responsible for BUN rise. Although ulcer was cured, the bodyweight decline was observed, which may have been due to accelerated urea production induced by Arg. Gln reinforcement, short energy supply and albumin decrease were observed. As hyperphosphatemia 6 . 8 mg/dL was observed at the time of ISOCAL ® Plus Ex administration, we recommend to take care to select an enteral nutrient with sufficient energy and electrolyte, and to monitor the bodyweight and blood parameters when administering Arg to hemodialysis patients.
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