Electrophoretic patterns of adult hemoglobins from two mouse strains, PON and Mol-A, are controlled by
Hbbd, an allele found only in a strain, AU/SsJ. Fresh hemolysate from
Hbbs/Hbbs mouse possesses a single hemoglobin, and the hemolysates from
Hbbd/Hbbd and
Hbbp/Hbbp mice contain two different hemoglobins in unequal amounts. The hemoglobin of
s homolysate is different from each of the major and minor hemoglobins of
d and
p, and the difference of hemoglobins between
d and
p is observed in the minor hemoglobin. All differences among these are derived from multiple allelic genes at one locus, which determines the structure of the hemoglobin β-chain polypeptide.
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