OBJECTIVES: During the 5-year period from 2001 to 2005, 4,075 patients with voice disorders were examined and treated at the Tokyo Voice Center. In this presentation the clinical records of these 4,075 patients were studied retrospectively. MATERIALS AND METHODS: The study involved an analysis of 4,075 patients (1,644 male, 2,400 female, 31 gender identity disorders (GID); 1 to 91 years of age; mean age, 44.1 years), mainly referred from other hospitals to the Tokyo Voice Center. In all patients, otolaryngologic, phoniatric and videostroboscopic examinations were completed. The clinical records of these patients were statistically studied with respect to distribution by age, sex, occupation, smoking, diagnosis, and relationship with vocal use as etiologic factors. RESULTS AND CONCLUSIONS: 1) Vocal fold nodules were most frequently diagnosed among organic diseases, followed by laryngitis and vocal fold polyps. Functional dysphonia was most frequently diagnosed among non-organic diseases, followed by epipharyngitis and spasmodic dysphonia. 2) Vocal fold nodules, laryngitis, vocal fold polyps, and vocal fold cysts were significantly related with vocal abuse. 3) Reinkeís edema, vocal fold leukoplakia, laryngeal cancers, vocal fold cysts, and vocal fold polyps were significantly related with smoking.
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