日本口腔外科学会雑誌
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
40 巻, 4 号
選択された号の論文の18件中1~18を表示しています
  • 上顎前方移動, 上方移動時における骨接触の検討
    後藤 哲, 川村 仁, 茂木 克俊
    1994 年 40 巻 4 号 p. 483-489
    発行日: 1994/04/20
    公開日: 2011/07/25
    ジャーナル フリー
    Bony contact after the maxilla had been mobilized by Le Fort I osteotomy was evaluated by computed tomographic examination of 52 Japanese dry skulls. The lateral piriform wall and the base of the zygomatic process of the maxilla which consist of thick bone are important areas to achieve good stability. Some cases of maxillary advancement and/or impaction lacked an osseous interface at the posterior wall. Preoperative CT along the osteotomy-line is recommended to achieve better postoperative stability.
  • 新鮮腫瘍細胞を用いての検討
    久保田 英朗, 田中 絹子, 香月 武, 黒河 博之, 今村 英夫
    1994 年 40 巻 4 号 p. 490-494
    発行日: 1994/04/20
    公開日: 2011/07/25
    ジャーナル フリー
    Fresh surgical specimens from 14 oral cancer patients were used for chemosensitivity tests by MTT assay.
    The chemosensitivity of 11 out of 19 samples taken from the patients was able to be assessed. The mean optical density (OD) of the control culture containing no drugs was 0.163, which was suitable for measuring the fine sensitivity of cells against various anti-cancer drugs. Squamous cell carcinomas (SCC) were highly sensitive to cisplatin (CDDP), followed by peplomycin (PEP) and 5-fluorouracil (5-FU).
    Synergistic growth inhibitory effect was detected against 2 SCC when PEP was used in combination with small amounts of CDDP. Thus, MTT assay was considered to be a useful chemosensitivity screening test for oral cancers.
  • 文 樹民, 辻 龍雄, 木村 由香, 伊田 正道, 佐々木 功典, 篠崎 文彦
    1994 年 40 巻 4 号 p. 495-500
    発行日: 1994/04/20
    公開日: 2011/07/25
    ジャーナル フリー
    This study was designed to investigate the relationship between immunohistochemical detection of p53 protein and pathological features in 101 cases of malignant salivary gland tumors (SGT). Immunoreactivity of p53 protein was observed in 24 of 101 (23.8%) cases of malignant SGT. The frequency of p53 immunoreactivity in various types of malignant SGT were: adenoid cystic carcinoma: 5/27 (18.5%); acinic cell carcinoma: 7/13 (53.8%); carcinoma in pleomorphic adenoma: 7/21 (33.3%); other types of adenocarcinoma including 3 cases of undifferential carcinoma: 5/15 (33.3%); mucoepidermoid carcinoma: 0/25. These data suggested that the expression of p53 protein was commonly involved in malignant SGT and that the p53 positive rate was different among various histological types of malignant SGT.
  • 斎木 康正, 中川 清昌, 熊谷 茂宏, 山本 悦秀
    1994 年 40 巻 4 号 p. 501-508
    発行日: 1994/04/20
    公開日: 2011/07/25
    ジャーナル フリー
    The purpose of the present study was to investigate the correlation between clinical findings and isolated organisms in 83 cases of suppurative infections of the oral and maxillofacial regions. This bacteriological study was performed by taking pus specimens from 83 closed abscesses. Eighty-three cases were divided into three groups by clinical features and courses. Included were severe infection type (81 strains in 19 cases), moderate infection type (106 strains in 27 cases), and light infection type (142 strains in 37 cases). The most common species were Streptococcus constellatus, Peptostreptococcus micros, Fusobacterium nucleatum and black-pigmented gram negative bacilli (Porphyromonas and some Prevotella). Most samples (71.1%) were a mixture of aerobes and anaerobes. Anaerobic bacteria were found in most of the samples (90.4%). The frequency of anaerobic infections was significantly higher in severe infection type than in other types. Gram positive cocci were the most common among severe and moderate infection types. Anaerobic gram positive cocci and anaerobic gram negative bacilli were significantly higher levels in severe and moderate types than in light type. These microbial findings suggested that gram positive cocci and anaerobic gram negative bacilli, especially blackpigmented anaerobic gram negative bacilli, may play an important role in the exacerbation of bacterial infections affecting the oral and maxillofacial regions.
  • 中村 典史, 樋口 勝規, 笹栗 正明, 原田 英光, 田代 英雄
    1994 年 40 巻 4 号 p. 509-513
    発行日: 1994/04/20
    公開日: 2011/07/25
    ジャーナル フリー
    Twenty-five ameloblastomas (19 primary and 6 recurrent) and 10 normal oral epithelia were evaluated by the streptavidin biotin immunoperioxidasemethod (SAB) to detect proliferating cell nuclear antigen (PCNA).
    PCNA-positive nuclei were identified in various intensities in both ameloblastomas and oral epithelia. In ameloblastomas, PCNA positive cells were found to be located mainly in the outer layer cells of the parenchymal nest of the tumor, while a few positive cells were observed in the inner cells, i. e. stellate cells and squamous cells. The average PCNA labelling index was 6.88% in ameloblastoma, and 8.6% in oral epithelium.
    PCNA labelling index was higher in recurrent cases than in primary cases. Expression of PCNA corresponded with histological growth patterns and type of outer layer cells, i. e. PCNA was detected in the basal cell type more than in the cuboidal cell and the columnar cell types. The above results suggest strong cell proliferation activity in the basal cell type.
  • ゲンタマイシン-PMMAビーズの応用
    生澤 操, 松本 憲, 奥西 泰子, 西山 知英, 千足 浩久, 作田 正義
    1994 年 40 巻 4 号 p. 514-518
    発行日: 1994/04/20
    公開日: 2011/07/25
    ジャーナル フリー
    We treated six cases of postoperative infection in the oral and maxillofacial region using gentamicin-impregnated polymethylmethacrylate (PMMA) beads (gentamicin-PMMA beads) from 1987 to 1990. Included were two benign tumors, one cyst, and three malignant tumors of the mandible. GM beads were temporarilly implanted into the dead space following debridement and were removed after 10-50 days. All cases were cured in a short time, without any side effects. In three of the four patients in whom the mandible was reconstructed at primary surgery with iliac bone or metal plates, these inplants did not have to be removed.
  • 由良 晋也, 戸塚 靖則, 樋田 京子, 門脇 繁, 小林 隆, 津山 昌嗣, 山口 泰彦, 井上 農夫男, 原田 浩之, 大類 晋, 畔田 ...
    1994 年 40 巻 4 号 p. 519-524
    発行日: 1994/04/20
    公開日: 2011/07/25
    ジャーナル フリー
    To evaluate the efficacy of lavage manipulation technique, 15 patients with persistent closed lock of the TMJ were treated by this method. The patients consisted of 1 male and 14 females. Age of the patients ranged from 18 to 66 years, with an average age of 33 years.
    This technique was followed by pumping of the upper compartment to distend the joint space after local anesthesia with sedation in the outpatient clinic. Two 18-gauge needles were inserted into the superior compartment to enable a free flow of the solution through the joint space. Physiological saline solution was injected via one of the needles under a sufficient pressure to irrigate 200 to 500 ml of the solution a during 20-minute period. During a 3-month follow-up of the method, interincisal mouth opening of the patients improved from a range of 7 to 25 mm, with an average opening of 14.9 mm.
    The results indicate that lavage manipulation technique is an effective method for treating patients with closed lock which can be performed under local anesthesia with sedation in the outpatient clinic.
  • 高戸 毅, 赤川 徹弥, 古森 孝英, 森 良之, 米原 啓之, 須佐美 隆史
    1994 年 40 巻 4 号 p. 525-527
    発行日: 1994/04/20
    公開日: 2011/07/25
    ジャーナル フリー
    Many operative techniques for correction of residual unilateral cleft lip nasal deformity have been reported. The authors have used the cartilage suspension technique by the external approach for patients school age. The majority of patients are operated on between the ages of 5 and 7 years based on the need for a “tidy appearance” by first grade. Regardless of the technique used by the authors, the incidence of poor correction and/or recurrence appeared to be high. A bulbous nose was very common after puberty. Wide dissection of the lower nose and excessive plication of the lower lateral cartilage were the main reasons for this unfavourable result.
    The authors describe our present technique for correcting residual unilateral cleft lip nasal deformity at school age. This procedure involves: 1. an open method to expose and correct lower lateral cartilage deformity. 2 The lower lateral cartilage on the cleft side is elevated and matched to the cartilage on the noncleft side by advancing it superiorly and cephalad. 3. Augmentation of the nasal tip and perialar sulcus is performed with a free conchal cartilage graft. This technique has been more rewarding than the other techniques we have attempted.
  • 堀川 正, 中川 泰年, 久保田 英朗, 後藤 昌昭, 香月 武
    1994 年 40 巻 4 号 p. 528-530
    発行日: 1994/04/20
    公開日: 2011/07/25
    ジャーナル フリー
    We performed high-dose methotrexate (MTX) citrovorum factor therapy in combination with adriamycin (ADM) and cisplatin (CDDP) in two patients with osteosarcomas originating in the mandible. The patients were treated with this chemotherapy regimen before and after surgery. Serum concentrations of MTX at 12, 48 and 72 hours postinfusion were examined. Leucovorin was administered frequently to prevent toxic effects of MTX on normal cells. No severe side effects were detected in case 1, but bone marrow suppression and liver dysfunction as well as gastrointestional hemorrhage occurred in case 2. Four years (case 1) and two years (caes 2) have passed since operation, and there are no signs of metastasis or recurrence.
  • 佐藤 明, 原田 浩之, 山崎 裕, 野谷 健一, 福田 博
    1994 年 40 巻 4 号 p. 531-533
    発行日: 1994/04/20
    公開日: 2011/07/25
    ジャーナル フリー
    We investigated the inpatients detected to have methicillin-resistant Staphylococcus aureus (MRSA) in our department. MRSA was isolated from 12 (24.5%) of 49 patients who were bacteriologically examined from April 1991 to February 1992. MRSA was detected primarily in patients with malignant tumors who had various underlying diseases, and most MRSA isolates were obtained from the sputum. Two of 12 patients developed MRSA infection. Bacteriological examination and the status of antibiotic usage in our department suggest that MRSA spread as a nosocomial infection via the medical staff. These results indicate the vital importance of preventing MRSA from spreading to compromised hosts.
  • 市川 健司, 盛実 俊也, 中村 謙一, 吉賀 浩二, 高田 和彰, 伊東 博司
    1994 年 40 巻 4 号 p. 534-536
    発行日: 1994/04/20
    公開日: 2011/07/25
    ジャーナル フリー
    A case of localized amyloidosis of the hard palate is reported. A71-year-old man visited our department complaining of bleeding from a tumor of the palatal mucosa. A biopsy specimen was taken from the tumor and it was diagnosed as amyloidosis. Detailed clinical examinations were performed to determine the type of amyloidosis. However, there were no signs suggesting that he was suffering from any associated disease such as rheumatoid arthritis or that diseases affecting other organs such as the thyroid, heart, kidney, liver, skin, stomach or bone marrow were involved. Based on this evidence, we judged that the lesion was isolated. The tumor was resected surgically and the defect was restored with an atelocollagen dermal substitute. Immunohistochemical study revealed that the fibrils accumulated in the tumor were AL (Aλ) amyloid protein.
  • 茅田 義明, 吉賀 浩二, 門前 敬子, 谷本 裕, 中村 謙一, 高田 和彰
    1994 年 40 巻 4 号 p. 537-539
    発行日: 1994/04/20
    公開日: 2011/07/25
    ジャーナル フリー
    Left lung complete collapse suddenly occurred after operation for a mandibular fracture in a patient with multiple injuries including mandibular and malar bone fractures, elbow fractures and thoracic injuries. Although the patient complained of no thoracic discomfort before operation, thoracotomy revealed complete atelectasis due to bronchial rupture caused by the traffic accident. A rare possibility of latent bronchial rupture, which lacks typical symptoms such as pneumomediastium and deep cervical emphysema after sustaining trauma has to be taken into account when treating patients with maxillofacial and thoracic injuries.
  • 古森 孝英, 横山 恵以子, 中津留 誠, 高戸 毅, 赤川 徹弥
    1994 年 40 巻 4 号 p. 540-542
    発行日: 1994/04/20
    公開日: 2011/07/25
    ジャーナル フリー
    Three-dimensional models from computer-aided three-dimensional images were created, and simulated surgery was performed. Anatomical structure was accurately reproduced, and the models allowed the simulated surgery to be performed in a manner very close to that of actual surgery.
    In this report we present a case of jaw deformities and discuss the usefulness and inherent problems of this method.
  • 萩原 寛司, 冲津 光久, 永峰 浩一郎, 嶋田 淳, 吉川 正芳, 山本 美朗
    1994 年 40 巻 4 号 p. 543-545
    発行日: 1994/04/20
    公開日: 2011/07/25
    ジャーナル フリー
    Two brothers with cleidocranial dysostosis were encountered. The younger brother first presented with a complaint of masticatory difficulty. X-ray examination revealed the presence of 27 impacted teeth and absence of the clavicles. The case was managed by fenesteration and tooth traction.
    Close examination of the older brother, performed on suspicion of the same disease, also revealed the presence of 25 impacted teeth and absence of the clavicles. In Japan at least 270 cases of this disease have been reported in the literature. In 117 of them, the disease was familial. By assay with an X-ray microanalyzer, the Ca and P contents in the mandibular bone did not differ between our patients and normal adults.
  • 大林 由美子, 三宅 実, 新谷 浩成, 谷崎 明弘, 長畠 駿一郎
    1994 年 40 巻 4 号 p. 546-548
    発行日: 1994/04/20
    公開日: 2011/07/25
    ジャーナル フリー
    5-year-survival rates for malignant melanomas occurring in the oral cavity are very low compared with the typical melanomas occurring on the skin's surface. This is most likely due to difficulty in early detection of tumors orising in the oral cavity and in performing extensive radical surgery in the maxillofacial region.
    A malignant melanoma treated succcessfully with DAV chemotherapy and administration of high dose interferon-β is reported. Before operation, a single cycle of DAV chemotherapy and local administration of interferon-β(1, 800×104 IU) were carried out. The tumor in the oral lesion was resected and total neck dissection was perfomed. Postopelatively, double cycles of DAV chemotherapy and systemic administration of high dose interferon-β(total 15, 100×104 IU) were carried out.
    In the three years that have passed since the first treatment, neither local recurrence nor distant metastasis have been detected clinically. However, it is important to continue follow-up because clinic statistics indicate that malignant melanoma has a high recurrence rate.
  • 片桐 三恵, 安藤 智博, 金子 裕之, 丸岡 靖史, 三宮 慶邦, 扇内 秀樹
    1994 年 40 巻 4 号 p. 549-551
    発行日: 1994/04/20
    公開日: 2011/07/25
    ジャーナル フリー
    Warthin's tumor is a comparatively rare benign epithelial tumor of the salivary glands, which most frequently arises in the parotid gland. In this article, we describe a case of multicentric Warthin's tumor involving the bilateral parotid glands. The patient was a 56-year-old man who presented at our department complaining of bilateral parotid swelling. Imaging studies showed two tumors in the left parotid gland one in the right parotid gland.
    The clinical diagnosis was bilateral parotid Warthin's tumors, and the lesions were surgically resected. The left tumor measured 4.7×3.5×3.0 cm and was multiple while the right tumor measured 4.8×3.0×3.0 cm.
    The histologic diagnosis was multicentric Warthin's tumor. There has been no recurrence as of 2 years and 11 months after the operation.
  • 渡辺 正人, 金子 忠良, 里見 貴史, 小野 健児, 渡辺 裕之, 南雲 祐二
    1994 年 40 巻 4 号 p. 552-554
    発行日: 1994/04/20
    公開日: 2011/07/25
    ジャーナル フリー
    Benign cementoblastoma is an odontogenic tumor of mesenchymal origin characterized by a mass of cementum-like tissue or cementum. It is also called a “true cementoma” by many workers, and is a rare lesion. This tumor most frequently involves a lower premolar or molar and is contiguous to the tooth root.
    The lesion described here occurred in a 26-year-old woman. It was located at the level of left lower second molar.
  • 吉田 精司, 土田 雅久, 稲田 育久, 吉岡 稔, 松塚 裕弘, 杉村 正仁
    1994 年 40 巻 4 号 p. 555-557
    発行日: 1994/04/20
    公開日: 2011/07/25
    ジャーナル フリー
    This case report describes a lateral-superior displacement of the mandibular condyle of a 44-year-old man who had been injured in a trafic accident. At admission, he presented with complete left facial nerve palsy. Radiological examination demonstrated fractures of the mandible in the right condylar and symphyseal regions, with lateral-superior displacement of the intact left condyle, which was lying above the zygomatic arch.
    After repositioning the left condyle into a normal position, the right condylar and symphyseal fractures were reduced and fixed.
    After 7 months follow-up, the temporo-mandibular joint function is normal and the facial paralysis has almost resolved with conservative therapy.
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