日本口腔外科学会雑誌
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
40 巻, 9 号
選択された号の論文の9件中1~9を表示しています
  • 山野 精一
    1994 年 40 巻 9 号 p. 963-973
    発行日: 1994/09/20
    公開日: 2011/07/25
    ジャーナル フリー
    Sjögren's syndrome (SS) is an autoimmune disease that is characterized by dryness of the mouth and eyes. The loss of salivary and lacrimal gland function is accompanied by lymphocytic infiltration. Because similar symptoms and glandular pathology are observed in certain persons infected with human immunodeficiency virus (HIV), a search was initiated for a possible retroviral etiology in this syndrome. To investigate the possibility of an immune response to retroviral antigens or that of detecting retrovirus in primary SS, I performed immunoblotting assay, immunohistochemical assay, polymerase chain reaction (PCR), and reverse transcriptase (RT) activity assay. Sera from 33% of 15 patients with SS, reacted against p24 group specific antigen (gag) of HIV. Labial salivary gland biopsy specimens from 47% of the 15 patients with SS contained an epithelial cytoplasmic protein reactive with a monoclonal antibody to p24 of HIV. I performed PCR to detect HIV and human T lymphotropic virus type I (HTLV-I)genes in salivary gland tissues and peripheral blood mononuclear cells (PBMC) from patients with SS. I also detected Mn2+ dependent, Mg2+ independent RT activity in the salivary gland tissues in 3 of 10 patients with SS. Target genes for HIV and HTLV-I were not found in any of the salivary gland tissues or PBMC from patients with SS. These data suggested the presence of an unknown retrovirus similar to HIV in the salivary gland that may contribute to chronic inflammation in SS.
  • 浅田 洸一, 長島 弘征, 長谷川 泰章, 中川 洋一, 石橋 克禮
    1994 年 40 巻 9 号 p. 974-980
    発行日: 1994/09/20
    公開日: 2011/07/25
    ジャーナル フリー
    Clinically, more reliable methods of estimating tenderness are needed. A pressure pain meter is an investigative tool for the measurement of tenderness. The purpose of this research was to measure the pressure pain threshold (PPT), and to compare topographic variability in PPT in the maxillofacial regions of normal subjects. PPT is the minimum pressure inducing pain or discomfort. The pressure pain meter consists of a force gauge to which a resin disc with a 1-cm diameter surface is attached. Normal threshold values were established in 22 volunteers (11 women and 11 men), at 6 different sites of the facial skin, including the mental protuberance (surface of the mandible), mental foramen and infraorbital foramen, lateral pole of the condyle, and the temporal and masseter muscles.
    The results indicated mean PPT in the mental protuberance (surface of the mandible) to be 2144g in women and 2349g in men. PTT at the mental foramen and infraorbital foramen, pole of the condyle (mouth opening phase), and masseter muscle (relaxation phase) were significantly lower than the values measured at the mental protuberance (surface of the mandible) in both sexes.
    PTT at the pole of the condyle when the mouth was open was significantly lower than that measured when the mouth was closed.
    PTT at the masseter muscle region in relaxation phase was significantly lower than that measured in contraction phase.
  • 佐々木 忠昭, 今井 裕, 永島 知明, 朝倉 昭人
    1994 年 40 巻 9 号 p. 981-987
    発行日: 1994/09/20
    公開日: 2011/07/25
    ジャーナル フリー
    The expression of epidermal growth factor (EGF) was studied immunohistochemically in 33 head and neck squamous cell carcinomas in relation to the degree of malignancy. The results obtained were as follows:
    1. EGF immunoreactivity significantly correlated with tumor size and lymph node metastasis.
    2. EGF immunoreactivity significantly correlated with histological malignancy according to Anneroth's classification, especially in regard to the degree of nuclear polymorphism and mode of invasion.
    3. The 3 year-cumulative survival rates in low-, moderate-, and high-EGF positive immunoreactivity groups were 100.0, 75.0 and 10.0%, respectively, with a significant decrease in the survival rate being noted (P<0.01, P<0.05) for higher degrees of EGF positive immunoreactivity.
  • 森田 章介, 有家 巧, 中嶋 正博, 堀井 活子, 角熊 雅彦, 野阪 泰弘, 廣田 克征, 岡野 博郎
    1994 年 40 巻 9 号 p. 988-996
    発行日: 1994/09/20
    公開日: 2011/07/25
    ジャーナル フリー
    Some ameloblastomas consist of sparse small nests and strands of odontogenic epithelium associated with desmoplastic stroma. This type of ameloblastoma was designated as desmoplastic ameloblastoma in the new WHO classification of odontogenic tumors in 1992. Over the past 22 years from 1970 to 1991, we diagnosed 4 cases of desmoplastic ameloblastoma among 124 primary cases of ameloblastoma, and analyzed them clinically, radiologically and histopathologically.
    1. The age at the initial visit was the third decade or over. Three cases occurred in the mandible and one case in the maxilla. The incidence of desmoplastic ameloblastoma was 3.2% of all ameloblastomas in the jaw bones.
    2. Three cases occurred in the anterior to the first premolar region and one case in the anterior to the first molar. These tumors seemed to develop from the alveolar process.
    3. Radiologically, all cases showed a honeycomb appearance containing mottled or dotted radiopacities with ill-defined margins.
    4. Divergency of tooth roots was seen in all cases, and some roots showed prominent resorption.
    5. Grossly, all tumors were solid type. Histologically, small sparse nests which showed acanthomatous type, stroma containing abundant collagen fibers, and many irregularly shaped areas of lamenar bone were observed. In the irregular bone, bone resorption and formation was seen concomitantly. The tumor invaded the adjacent bone marrow.
    6. Marginal resection was performed in 3 cases and enucleation followed by curettage in one case. No recurrence was noted.
  • 瀬古 和秀, 各務 秀明, 光藤 健司, 水谷 英樹, 上田 実, 金田 敏郎
    1994 年 40 巻 9 号 p. 997-999
    発行日: 1994/09/20
    公開日: 2011/07/25
    ジャーナル フリー
    In this paper, we report a case of congenital ranula lying adjacent to a possible thyroglossal duct cyst. The patient was a newborn baby who presented no remarkable anomalies in other regions. He was referred to us by a gynecologist because of swelling of the oral floor and elevation of the tongue. There were no noteworthy findings in the patient's family or personal history, including during gestation. Our clinical diagnosis was a sublingual cyst. The cyst was surgically enucleated at 9 months old when his body weight reached 9 kg. The cyst consisted of two compartments, one superficial and the other deep, which were completely separate. From clinical and pathological findings, the superficial portion was diagnosed as a congenital ranula, and the deep cyst was supposed to be a thyroglossal duct cyst. A close etiological relationship was suggested between these two adjacent cysts.
  • 辻 龍雄, 文 樹民, 末次 正康, 葛山 司, 岡藤 正樹, 篠崎 文彦
    1994 年 40 巻 9 号 p. 1000-1002
    発行日: 1994/09/20
    公開日: 2011/07/25
    ジャーナル フリー
    Ameloblastic fibro-odontoma is a rare odontogenic tumor. Its proper classification has been often debated. An ameloblastic fibro-odontoma developing in the maxillary sinus of a 13-year-old girl is described in this paper. Radiographically, the lesion showed irregular rediopacity surrounded by monolocular radiolucency.
  • 南部 敏和, 奈良 潤一郎, 鳥谷部 純行, 大坪 誠治
    1994 年 40 巻 9 号 p. 1003-1005
    発行日: 1994/09/20
    公開日: 2011/07/25
    ジャーナル フリー
    Ultrafast ‘Turbo-FLASH’ MR Imaging is a convenient screening method for dynamic evaluation of temporomandibular joints. Using this technique, 15 sequential images could be obtained in 53 seconds and displayed as dynamic video images. Although spacial resolution of the images was not very good, the gross outline of the TMJ disc was clearly demonstrated as high signal structures in three normal cases.
  • 大島 和彦, 大多和 亜希, 吉賀 浩二, 高田 和彰, 小川 郁子, 高田 隆
    1994 年 40 巻 9 号 p. 1006-1008
    発行日: 1994/09/20
    公開日: 2011/07/25
    ジャーナル フリー
    Here we describe a clinically amelanotic malignant melanoma in the maxilla of a 49-year-old man. The tumor appeared as a slightly reddish mass without pigmentation. Examination of a biopsy specimen showed the tumor to be composed of a solid proliferation of round and spindle cells with atypia. Although not obvious in H-E-stained sections, melanin pigment was seen after Fontana-Masson staining in only a few tumor cells. Many tumor cells showed positive immunoreactivity for S-100 protein, NSE and antimelanoma antibody, HMB-45.
    Radiotherapy and chemotherapy were performed, and the primary and neck metastatic tumors regressed. However, the patient died of multiple distant metastases. Postmortem examination revealed darkly brown-stained peritoneal metastasis, but no pigmentation at other metastatic sites.
  • 里村 一人, 板東 泰博, 林 英司, 宮本 洋二, 長山 勝, 水口 潤
    1994 年 40 巻 9 号 p. 1009-1011
    発行日: 1994/09/20
    公開日: 2011/07/25
    ジャーナル フリー
    Recently, the results of treatment in patients with chronic renal failure have improved owing to progress in hemodialysis. Consequently, there is expected to be an increase in patients with head and neck cancer complicated by chronic renal failure. We performed radiation therapy, surgery and chemotherapy using cis-diamminedichloroplutinum (CDDP) and 5-fluorouracil ( 5-FU) to treat tongue cancer in a 60-yearold man with chronic renal failure who was undergoing hemodialysis. Here we present our results and discuss some problems in treatment. Close attention should be paid to unusual tumor growth when performing anticancer therapy for malignancy in patients undergoing hemodialysis for chronic renal failure.
feedback
Top