巻号一覧
46 巻, 1 号
選択された号の論文の13件中1～13を表示しています
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佐藤 文彦2000 年 46 巻 1 号 p. 1-8
発行日: 2000/01/20
公開日: 2011/07/25
ジャーナル フリーTransforming growth factor-alpha (TGFA) genes, transforming growth factor-beta 3 (TGFB 3) genes, and homeobox 7 (MSX 1) genes have been reported to contribute to cleft palate in mice. Many investigators have attempted to demonstrate that these candidate genes contribute to the development of cleft lip, cleft palate, or both (CL/P). Many ethnic groups have been studied, but candidate genes involved in the development of CL/P have not been identified.
We analyzed the association between candidate genes and CL/P, using a microsatellite polymorphism existing near the candidate gene in Japanese patients with CL/P and their parents. The affected familybased control method (AFBAC method) and transmission/disequilibrium test (TDT method) were used to evaluate all sets of comparisons.
Near the TGFB 3 gene, a significant difference was observed in frequency of the transmitted allele 1 from father or mother to the patient with CLP (AFBAC method: P=0.023, TDT method: P=0.014); differences in frequency were not found at other sites.
In conclusion, either the TGFB 3 gene itself or an adjacent DNA sequence may contribute to the development of CLP in the Japanese population, but no significant association was found between CL/P and the TGFA gene or MSX 1 gene.抄録全体を表示PDF形式でダウンロード (5814K) -
個性正常咬合者との比較と術前, 術後の経時的変化について永井 格, 巣山 達, 田中 信幸, 井手 隆, 宮崎 晃亘, 竹村 佳奈子, 小浜 源郁2000 年 46 巻 1 号 p. 9-15
発行日: 2000/01/20
公開日: 2011/07/25
ジャーナル フリーWe examined occlusal status in 18 patients with mandibular prognathism (mandibular prognathism group) as compared with that of 14 adults with normal occlusion (control group). We also studied changes in occlusal status after orthognathic surgery (1, 3, 6, and 12 months) in the patients with mandibular prognathism. The occlusal contact area, maximum voluntary isometric bite force, and occlusal pressure were recorded using a pressure-sensitive sheet (Dental Prescale ® 30HW type, Fuji Photo Film Co.) and the data were analyzed with an analysis system (FPD-703, Fuji Photo Film Co.).
The results were as follows:
1) Preoperatively, the mandibular prognathism group had a significantly smaller occlusal contact area and a lower bite force than the control group, but had a higher occlusal pressure.
2) Changes in occlusal contact area and bite force were evaluated in the patients with mandibular prognathism from before operation to 12 months after operation. Occlusal contact area and bite force decreased significantly 1 month after operation, increased significantly to preoperative levels 6 months after operation, and were about 40% of preoperative levels 12 months after operation. However, 12 months after operation occlusal contact area was smaller and bite force was lower than those in the control group.
3) Occlusal pressure was evaluated in the patients with mandibular prognathism from before operation to 12 months after operation. The value increased significantly 1 month after operation, but decreased subsequently. Twelve months after operation, occlusal pressure in the prognathism group was similar to that in the control group.
4) Few studies have used pressure-sensitive sheets. This method permits assessment of occlusal status of all teeth easily and promptly. Pressure-sensitive sheets are useful for understanding occlusal status clinically.抄録全体を表示PDF形式でダウンロード (3832K) -
松平 淳, 森田 展雄, 宮田 和幸, 畠 祥子, 和田 健, 坂本 忠幸2000 年 46 巻 1 号 p. 16-18
発行日: 2000/01/20
公開日: 2011/07/25
ジャーナル フリーAn elderly patient with recurrent carcinoma of the maxillary sinus, extending to the infraorbital region was treated by radiofrequency (RF) interstitial hyperthermia using needle-type applicators, combined with Transcatheter arterial embolization (TAE). TAE in the maxillary arterial region was performed with a stainless steel coil (non-degradable material). Multiple (6-8) needle-type applicators, made of stainless steel coated with gold, were inserted into the tumor in parallel at intervals of about 10mm.
Each other interstial hyperthermia with 60Co external irradiation (2 Gy/day total 20Gy) was repeated ten times.
The size of the tumor decreased markedly, and oral feeding disorders present before treatment resolved almost completely. Our results suggest that RF interstitial hyperthermia using needle-type applicators with embolization is effective in the treatment of selected cases of oral cancer.抄録全体を表示PDF形式でダウンロード (6405K) -
立石 晃, 平島 惣一, 三森 康弘, 村木 祐孝, 津山 昌嗣, 福田 仁一2000 年 46 巻 1 号 p. 19-21
発行日: 2000/01/20
公開日: 2011/07/25
ジャーナル フリーMany procedures have been described for reconstruction of the lips. Surgeons must strive to reconstruct an esthetic and functional lower lip. In 1974, Karapandzic described a procedure for reconstruction of lip defects by local arterial flaps. We describe a patient with buccal mucosa (lower lip mucosa) carcinoma in whom immediate reconstruction was performed using both a Karapandzic flap and a rhomboid flap. The outcome was satisfactory. A Karapandzic flap was particularly useful in reconstruction of the angulus oris.抄録全体を表示PDF形式でダウンロード (6281K) -
永易 裕樹, 小村 健, 山下 知巳, 藤田 善教2000 年 46 巻 1 号 p. 22-24
発行日: 2000/01/20
公開日: 2011/07/25
ジャーナル フリーA case of bilateral elongated styloid processes in a patient with cancer of the floor of the mouth is reported.
A 67-year-old man was referred to our hospital because of a tumor arising in the floor of the mouth. He had no symptoms suggesting styloid syndrome. Computed tomographic and radiographic examinations revealed bilateral elongated styloid processes. The tip of the right process extended to the lesser cornu of the hyoid bone and formed tubercle, and the tip of the left process extended to the level of the mandibular angle region. After radiotherapy for the cancer of the floor of the mouth, he underwent neck dissection, excision of the cancer, and shortening of the right styloid process. The surgical defect resulting from ablation of the cancer was reconstructed with the use of a free forearm flap. Histopathological examination of the styloid process showed that the cartilage of the tip had the potential to grow and mature to bony tissue in the future.抄録全体を表示PDF形式でダウンロード (3804K) -
中嶋 正博, 森田 章介, 蝿庭 秀也, 窪 寛仁, 濱本 和彦, 小川 文也2000 年 46 巻 1 号 p. 25-27
発行日: 2000/01/20
公開日: 2011/07/25
ジャーナル フリーAlveolar soft-part sarcoma is a rare malignant neoplasm of uncertain origin. We report a case of alveolar soft-part sarcoma arising in the right buccal mucosa in a 31-year-old woman.
The tumor measured 12×13×10mm. It was elastic soft and had ulceration on the surface. A granularcell tumor was suspected on examination of a biopsy specimen. The tumor was removed with the surrounding tissues. Histologically, the tumor consisted of large cells with eosinphilic cytoplasm. The cells showed distinct atypia and a nest-like arrangement.
PAS-positive diastase-resistant needle crystals were seen in the cytoplasm. Alveolar soft-part sarcoma was the final diagnosis. There has been no evidence of local recurrence or distant metastasis as of 1 year 6 months after operation.抄録全体を表示PDF形式でダウンロード (4014K) -
藤森 優子, 宇都宮 忠彦, 吉田 亨, 金田 隆, 山本 浩嗣, 名倉 英明2000 年 46 巻 1 号 p. 28-30
発行日: 2000/01/20
公開日: 2011/07/25
ジャーナル フリーMyoepithelioma is a relatively rare benign salivary gland tumor that mainly occurs in the palatal or parotid glands. We encountered a rare case of this tumor in the gingivobuccal fold.
The patient was a 54-year-old Japanese woman with a hemispherical globe-shape swelling. Computed tomography (CT) and ultrasonography showed a tumor in the gingivobuccal submucosa; there was no evidence of bone destruction. The tumor was surgically removed under the clinical diagnosis of a minor salivary gland tumor. Histologically, the tumor was composed mainly of plasmacytoid cells without malignant features. It was diagnosed as a myoepithelioma.
In the Japanese literature, 15 cases of myoepithelioma, including our case, have been reported during the past 10 years. The most common sites were the parotid gland (5 cases, 33.3%) and palate (5 cases, 33.3%). To our knowledge, this is the first case of a myoepithelioma arising in the gingivobuccal fold to be reported in the Japanese literature.抄録全体を表示PDF形式でダウンロード (3594K) -
萬野 幸代, 櫻井 一成, 橋谷 進, 西村 則彦, 高岡 一樹, 浦出 雅裕2000 年 46 巻 1 号 p. 31-33
発行日: 2000/01/20
公開日: 2011/07/25
ジャーナル フリーIntravascular papillary endothelial hyperplasia (IPEH) is a benign vascular lesion resembling hemangioma It rarely occurs in the oral mucosa and is histologically characterized by the papillary proliferation of endothelial cells during thrombus organization.
We report two cases of IPEH on the lower lip and the tongue. Because the lesion grows gradually, surgical excision is the treatment of choice.抄録全体を表示PDF形式でダウンロード (4041K) -
土居 三余子, 山本 哲也, 米田 和典, 木村 剛, 尾崎 登喜雄2000 年 46 巻 1 号 p. 34-36
発行日: 2000/01/20
公開日: 2011/07/25
ジャーナル フリーThis report describes a case of chemoradiotherapy-induced pulmonary tuberculosis (PTB). A 77-year-old patient with tongue carcinoma received chemoradiotherapy. A complete response was obtained with a combination of 60Co and intra-arterial infusion of peplomycin and 5-fluorouracil. However, near the end of treatment, pain of the glossopharyngeal region developed and gradually worsened. An analgesic (flurbiprofen axetil) and prednisolone (30mg/day) were intravenously injected to manage the unbearable severe pain, attributed to lingual arteritis. The glossal pain then gradually improved and almost subsided after 1 week of prednisolone treatment, but a high fever suddenly developed a few days later. Chest radiography revealed a round cavity-like lesion in the right upper lobe and acid-fast bacteria were cultured from sputum. In addition, PCR of the bacterial DNA identified the bacteria as Mycobacterium tuberculosis. Then, the patient was transferred to another hospital for treatment of PTB and received chemotherapy with isoniazid, rifampicin, and streptomycin. PTB responded to chemotherapy, and the patient was discharged from the hospital after 3 months. The outcome of the tongue lesion was good, although the patient received extirpation of metastatic submandibular lymph nodes. The present case shows that caution is required against PTB in patients receiving therapy for oral cancer.抄録全体を表示PDF形式でダウンロード (5553K) -
山田 耕治, 井関 富雄, 渡邉 岳, 白数 力也2000 年 46 巻 1 号 p. 37-39
発行日: 2000/01/20
公開日: 2011/07/25
ジャーナル フリーA case of tuberculosis of the gingiva in a 54-year-old man with active pulmonary tuberculosis is described. Intraoral examination revealed irregularly shaped ulcers in the right maxillary and left mandibular gingiva. Oral tuberculosis is considered an uncommon lesion with various characteristics. It is often difficult to distinguish oral tuberculosis from other conditions, such as carcinomas. In our patient, a biopsy was performed under a clinical diagnosis of a malignant tumor. The pathological findings suggested tuberculosis of the gingiva. A chest X-ray examination showed extensive active pulmonary tuberculosis, and cultures of the sputum showed tubercle bacilli. Treatment with INH, RFP, and EB was effective; the pain and ulceration in the gingiva disappeared within 3 weeks抄録全体を表示PDF形式でダウンロード (3593K) -
小早川 元博, 近藤 壽郎, 亀井 和利, 山田 友康, 今村 栄作, 瀬戸 皖一2000 年 46 巻 1 号 p. 40-42
発行日: 2000/01/20
公開日: 2011/07/25
ジャーナル フリーThis report describes a patient who underwent two-jaw osteotomy with simultaneous reconstructive surgery of the temporomandibular joint (TMJ) using an autologous costochondral graft. The patient had skeletal malocclusion and facial asymmetry caused by dislocation and resorption of the condyle associated with a previous fracture. We planned the operation to prevent a postoperative continuous decrease in ramus height. Postoperatively, the provision of posterior support for the decreased ramus height was useful in maintaining stable occlusion and facial asymmetry. There was no postoperative ankylosis of the TMJ, and the grafted cartilage-bone complex underwent remodeling physiologically.
We conclude that costicartilage is a suitable material for TMJ reconstruction and maintaining ramus height.抄録全体を表示PDF形式でダウンロード (3008K) -
須賀 賢一郎, 近藤 千恵, 相川 弦, 渡辺 一, 齊藤 力, 橋本 貞充2000 年 46 巻 1 号 p. 43-45
発行日: 2000/01/20
公開日: 2011/07/25
ジャーナル フリーWe report a case of an extravasation mucous cyst extending from the submandibular gland to the base of the skull.
A 25-year-old woman had noticed a painless swelling of the left submandibular gland region for 2 months. There was a well-delineated, fluctuating swelling on palpation. Intraorally, there was no swelling in the floor of the mouth nor pus discharge from Wharton's duct; salivary flow was good. Imaging by computed tomography and magnetic resonance showed a cystic lesion extending from the submandibular gland to the base of the skull via the parapharyngeal space. Since the lesion was not connected to the sublingual gland, surgical extirpation of submandibular gland was carried out under general anesthesia.
Histopathological examination indicated an extravasation mucous cyst. There has been no evidence of recurrence as of 18 months after the operation.抄録全体を表示PDF形式でダウンロード (6186K) -
劉 文憲, 古賀 千尋, 岩本 修, 木原 俊之, 亀山 忠光2000 年 46 巻 1 号 p. 46-48
発行日: 2000/01/20
公開日: 2011/07/25
ジャーナル フリーWe usually use Vitapex® as a root canal filling. This report describes a case of inferior alveolar nerve hypoesthesia caused by overfilling a root canal with Vitapex®.
Case: A 23-year-old woman was referred to our hospital because of hypoesthesia of the inferior alveolar nerve.She had undergone treatment of 7 with root canal filling using Vitapex® one week earlier at another clinic. On the following day, she had hypoesthesia of the skin of the right side of the chin. X-ray examination showed a radiopacity in the right mandibular canal.After 4 months of conservative management, hypoesthesia decreased.Soon after, we extracted 7.
Her subsequent course has been uneventful, and only a small hypoesthestic area remains.抄録全体を表示PDF形式でダウンロード (6252K)
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