日本口腔外科学会雑誌
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
46 巻, 6 号
選択された号の論文の17件中1~17を表示しています
  • 野村 武史, 野間 弘康, 柴原 孝彦
    2000 年 46 巻 6 号 p. 317-329
    発行日: 2000/06/20
    公開日: 2011/07/25
    ジャーナル フリー
    The purpose of this study was to clarify the effects of long-term ethanol and acetaldehydeconsumption on histopathological changes in rat tongue epithelium.
    One hundredeight male Wistar rats (300g body weight) were divided into 4 groups. The ethanol group (n=29) was given a 5% ethanol diet (ORIENTAL YEAST). The control group (n=33) was fed a control diet (ORIENTAL YEAST). Moreover, the tongue epithelium was coated daily with acetaldehyde (AA) at a concentration of 180m M in the daily AA (n=22) and ethanol+ AA groups (n=24). Animals were killed after 24 weeks. Their tongues were removed, and dorsal, lateral, and sublingual sites. Were studied histologically by H-E staining, histochemical anti-PCNA staining, and SEM.
    In the AA and ethanol+AA groups, the keratic thickness of the dorsal and sublingual sites had significantly increased (AA: p<0.05, ethanol+ AA: p<0.01, vs control and Ethanol groups). Epithelial thickness and cell number in the three sites did not significantly differ among the groups. In the ethanol, AA, and ethanol+AA groups, PCNA positive cells in the basal layer increased considerably (p<0.01, vs control group). Moreover, in the AA and ethanol+AA groups, PCNA-positive cells in the lower 1/3 of the epithelial layers significantly increased (p<0.01, vs control and ethanol groups). Nine cases of hyperkeratosis were found at the dorsal prominence of the tongue, 1 in the ethanol group (3.4%), 2 in the AA group (9.1%) and 6 in the ethanol+ AA group (25.0%).
    Acetaldehyde, a primary metabolite of ethanol may play a direct role in the pathogenesis of tongue cancer in the rat.
  • 榊 敏男, 和唐 雅博, 山根木 康嗣, 門田 秀隆, 中嶋 正博, 森田 章介, 田中 昭男, 覚道 健治
    2000 年 46 巻 6 号 p. 330-335
    発行日: 2000/06/20
    公開日: 2011/07/25
    ジャーナル フリー
    We immunohistochemically examined the expression of E-cadherin (E-CD), α-catenin (α-CAT), and nuclear proliferating antigen Ki-67 in 5 granular cell ameloblastomas to investigate their biological characteristics. Expressed Ki-67 antigen was localized within the nucleus of only peripheral columnar/cuboidal cells. The mean Ki-67 labelling index was low (1.47%). Expression of E-CD and α-CAT was observed at the cell-cell boundaries of all peripheral columnar/cuboidal cells and some granular cells near the peripheral portion of the tumor nests. However, there was reduced expression of E-CD and α-CAT in granular cells at the central portion of the tumor nests.
  • 五味 暁憲
    2000 年 46 巻 6 号 p. 336-347
    発行日: 2000/06/20
    公開日: 2011/07/25
    ジャーナル フリー
    The purpose of this study was to investigate the effect of a Hotz plate on development of the maxillary alveolar arch. Gypsum models were obtained from 12 patients with unilateral cleft lip and palate (UCLP) who were treated with a Hotz plate at the time of presentation, lip repair, and palate repair. The models were then measured three-dimensionally with a device called “SURFLASER VMS-250R” (UNISUN Co.). Ten patients who did not wear a Hotz plate were studied as control. In this group, gypsum models were taken at the time of palate repair.
    Results:
    1. Before setting the Hotz plate, the incisive point was situated on the normal side away from the midplane. Cleft width was 9.4 ± 3.4mm at the alveolar region, 10.3 ± 3.0mm at the anterior palatal region and 12.6 ± 1.5mm at the posterior palatal region.
    2. After setting the Hotz plate, the incisive point moved in the anterior, inferior, and medial directions close to the midplane. The tip of the cleft edge on the major segment moved in the anterior, inferior, and lateral directions, and the cleft edge on the minor segment shifted anteriorly and medially. The anterior cleft margin of the major segment moved in the inferior and medial directions, and the minor segment moved medially. The posterior region of the cleft margin bilaterally moved to a more superior and medial position. Thus, the cleft narrowed to 2.9 ± 2.9mm at the alveolar region, 1.8 ± 1.9mm at the anterior palatal region and 8.8 ± 2.3mm at the posterior palatal region. The rate of increase in the superficial content of the minor segment was greater than that of the major segment.
    3. The incisive point and canine points were situated more anteriorly in patients with a Hotz plate than in patients in the control group. Furthermore, the superficial content of the palatal surface in patients with a Hotz plate was significantly larger than that in the control group.
    4. Our results suggest that the Hotz plate is effective not only for adjusting the alveolar arch form but also for increasing palato-alveolar growth.
  • 河原 康, 堀田 文雄, 遠矢 東誠, 水島 睦枝, 白水 敬昌, 宮地 斉
    2000 年 46 巻 6 号 p. 348-350
    発行日: 2000/06/20
    公開日: 2011/07/25
    ジャーナル フリー
    Fibro-osseous lesions of the craniofacial bones are a challenging group of pathologicconditions that are difficult to classify. Unfortunately, there are no universally accepted clinical, radiographic, or histopathologic criteria that categorically distinguish these lesions from one another. A case ofbenign oseoblastoma of the right side of the mandible with diverse histopathologic findings is reported. Thepatient was a 9-year-old Spanish-Peruvian girl who presented with enlargement of the right side of themandible of 4 months' duration. Mandibular radiographs showed a well circumscribed mass containing both radiopaque and radiolucent lesions without periosteal spiculated new bone formation. Extirpation and curretage of the lesion were done. Histologically, the tumor was composed of lesions cosistent withbenign osteoblastoma. The peripheral region of the tumor mimicked fibrous dysplasia, cemento-ossifying fibroma, and sclerosing osteomyelitis. The final diagnosis was mandibular benign osteoblastoma. One year 8 months postoperatively, the patient was well, with no sign of recurrence.
  • 西口 浩明, 萩野 浩子, 泉 由里子, 宇佐美 雄司, 上田 実
    2000 年 46 巻 6 号 p. 351-353
    発行日: 2000/06/20
    公開日: 2011/07/25
    ジャーナル フリー
    We report a case of osteoma with a dentigerous cyst occurring in the maxillary sinus of a 24-year-old woman. The patient was referred to our hospital because of a radiopaque lesion in the left maxillary sinus. Computed tomographic examination revealed a high density radiopaque lesion containing a cystic lesion. The mass, measuring 16.5 × 14.0 × 18.5mm, and the cyst were removed surgically via the canine fossa with the patient under general anesthesia. The histopathological diagnosis was osteoma spongiosum with a dentigerous cyst. This case is very rare with respect to the structure and location of the lesion.
  • 細胞増殖能に関する比較検討
    北村 英二, 岡田 裕之, 金田 隆, 武田 譲, 山本 浩嗣, 名倉 英明
    2000 年 46 巻 6 号 p. 354-356
    発行日: 2000/06/20
    公開日: 2011/07/25
    ジャーナル フリー
    Benign cementoblastoma, which is classified as a true cementoma by the WHO's histological typing of odontogenic tumours (1992), is contiguous with tooth roots and is characterized by formation of a cement-like tissue sheet containing many reversal lines and unmineralized peripheral areas. To our know ledge, there has been no report about the proliferative activity of cells in this tumor. We studied a benign cementoblastoma arising in the mandibular right first molar of a 20-year-old man and immunohistochemically evaluated the proliferative activity of its cells with the use of proliferating cell nuclear antigen. The positive cell rate of cementoblasts and enclosed cells were 36.2% and 18.5%, respectively. These rates were higher than those of extracted tooth cement (15.0%, 0%), studied as control. This study clearly demonstrated that the tumor cells had high proliferative activity, suggesting that the lesion is a true tumor. The literature of Japan, Europe, and America on this tumor was reviewed. There is considerable predilection with respect to location.
  • 道念 正樹, 村上 有二, 高野 昌士, 鈴木 豊典, 飯塚 正, 戸塚 靖則
    2000 年 46 巻 6 号 p. 357-359
    発行日: 2000/06/20
    公開日: 2011/07/25
    ジャーナル フリー
    A case of spindle cell lipoma of the tongue is presented. The patient, a 71-year-old man, had a painless swelling of the tongue. Physical examination revealed two discrete, tender masses in the left ridge of the tongue. These masses were removed surgically. Histopathologically, they consisted of small groups of mature lipocytes separated by spindle cells and of stroma to composed of bundles of collagen fibers and mucinous materials. The spindle cells had a single fusiform nucleus. The histopathological diagnosis was spindle cell lipoma. Spindle cell lipoma commonly arises in the posterior neck, upper back, and shoulders and is extremely rare in the oral cavity. Only nine cases have been reported in the literature.
  • 西原 昇, 安藤 智博, 山崎 卓, 岡本 俊宏, 深田 健治, 扇内 秀樹
    2000 年 46 巻 6 号 p. 360-362
    発行日: 2000/06/20
    公開日: 2011/07/25
    ジャーナル フリー
    An angiomyoma is a benign tumor usually located in the lower extremities of middle-aged women. It is rarely found in the oral region. We report a case of angiomyoma arising in the hard palate. A 39-year-old man was referred to our clinic because of a painless mass in the hard palate. The tumor measured about 8 × 8 mm and was a localized, elastic soft, mucosal swelling of the hard palate. The histopathological diagnosis was angiomyoma. Postoperative observation has revealed no recurrence, as of 4 years after surgery.
  • 平田 康, 天笠 光雄, 小室 千鶴子, 鵜澤 成一, 妻鹿 宏子, 高木 実
    2000 年 46 巻 6 号 p. 363-365
    発行日: 2000/06/20
    公開日: 2011/07/25
    ジャーナル フリー
    We report a rare case of a dentigerous cyst associated with a cementomatous lesion in the left side of the maxilla. The patient was a 42-year-old man who had swelling of the left side of the cheek. Radiographic examination showed a cystic lesion with opaque foci around an impacted wisdom tooth. Computed tomography (CT) revealed that the cystic lesion measured 30 × 20 × 20 mm. The lesion was surgically treated by enucleation with radical sinusotomy and extraction of an impacted wisdom tooth, performed with the patient under general anesthesia. Histopathological examination revealed that the cyst wall was lined by non-keratinized squamous epithelium and a cementomatous lesion was seen around the impacted wisdom tooth.
  • 桐山 健
    2000 年 46 巻 6 号 p. 366-368
    発行日: 2000/06/20
    公開日: 2011/07/25
    ジャーナル フリー
    From May 1996 through December 1997, 306 patients with multiple traumas were treated at the Critical Care Medical Center of Hiroshima Prefectural Hospital. Of these patients, 110 (35.9%) had maxillofacial injuries. These patients with maxillofacial injuries were studied.
    The results were as follows:
    1) The most common cause of trauma was traffic accidents (81.9%).
    2) Common coexisting injuries in the 110 patients with maxillofacial injuries were injuries of the extremities and pelvis (51.8%), skull and brain (33.6%), and thorax and lung (30.9%).
    3) Maxillofacial injuries did not affect the prognosis of patients with multiple traumas.
    4) Twenty-six (23.6%) patients had maxillofacial fractures. There were 48 facial fractures in 26 patients. Midface fractures were most common (31/48, 64.5%), while mandibular fractures were less frequent (14/48, 29.2%).
    5) Of the 26 patients with maxillofacial fractures, airway obstruction necessitating tracheostomy was present in 5 (19.2%).
    6) Le Fort II, M and median fractures of maxilla increased as compared with the incidence in our previous study (from 1986 through 1993).
    Our study showed that facial injuries were often present in the patients with multiple traumas. Oral and maxillofacial surgeons therefore play an important role in the care of patients with polytrauma who have facial injuries.
  • 原田 清, 米澤 久信, 盛島 聖子, 平野 泰正, 大倉 一徳, 榎本 昭二
    2000 年 46 巻 6 号 p. 369-371
    発行日: 2000/06/20
    公開日: 2011/07/25
    ジャーナル フリー
    Two children who had cleft lip and palate with severe maxillary hypoplasia were treated by maxillary distraction osteogenesis. They underwent a high Le Fort I osteotomy and maxillary advancement with distraction osteogenesis, performed with the use of an external, adjustable, rigid distraction device (Rigid External Distraction (RED) System®). The skeletal and soft-tissue midface defects were improved. Their occlusion was also corrected. This report describes the surgical technique, application procedure, and preoperative and postoperative management for the RED System. In addition, the advantages and disadvantages of the system are discussed.
  • インプラント治療における骨移植への有用性
    澤 裕一郎, 川野 大, 福井 克仁, 中山 敦史, 土井田 誠, 宮城島 俊雄
    2000 年 46 巻 6 号 p. 372-374
    発行日: 2000/06/20
    公開日: 2011/07/25
    ジャーナル フリー
    Bone grafts are useful for the placement of implants in atrophic bone in edentulous regions. Usually, grafted bone undergoes resorption and provides inadequate support for implants. The guided bone regeneration (GBR) method can prevent resorption of grafted bone; however, GBR has some disadvantages, including exposure of the membrane and infection. Platelet rich plasma (PRP) accelerates wound healing by autologous growth factors. We consider growth factors of PRP to promote sufficient bone for implants. In this study, we used PRP gel to graft, bone harvested from the chin to the anterior maxillary region, which had undergone resorption. After 14 weeks, we decided that there was sufficient bone in the region on computed tomographic examination. After 16 weeks, implants were able to be placed, despite bone resorption. Biopsy of bone specimens revealed active osteogenesis and bone remodeling. Our results suggest that PRP could accelerate bone healing and remodeling, but could not prevent bone resorption in a similar manner to GBR. We confirmed that PRP gel is beneficial at the time of bone grafting for implants.
  • 山田 芽, 早津 良和, 水柿 雄三, 篠崎 文彦
    2000 年 46 巻 6 号 p. 375-377
    発行日: 2000/06/20
    公開日: 2011/07/25
    ジャーナル フリー
    Approximately 60% of all actinomycotic infections occur in the cervicofacial area. The submandibular region is the most frequent site, and actinomycosis of bone is rare. We report a rare case of actinomycosis arising in the maxilla.
    The patient was a 51-year-old woman who presented with a diffuse swelling and purulent fistulas in the left maxillary molar region. Radiography revealed an irregular radiopaque mass surrounded by a radiolucent area in the left maxillary molar region. The left maxillary sinus was cloudy. Computed tomography showed hone destruction appearing to be a sequestrum in the left maxillary molar region with severe mucosal thickening of the left maxillary sinus.
    The clinical diagnosis was chronic osteomyelitis of the maxilla with spontaneous sequestration and chronic maxillary sinusitis. The sequestrum was removed, and radical antrum operation was performed with the patient under general anesthesia. The histopathological diagnosis was actinomycosis with a sequestrum.
  • 長谷川 正午, 堀田 文雄, 河原 康, 遠矢 東誠, 白水 敬昌, 宮地 斉
    2000 年 46 巻 6 号 p. 378-380
    発行日: 2000/06/20
    公開日: 2011/07/25
    ジャーナル フリー
    The preepiglottic space is located in front of the epiglottis. It is an extremely narrow space surrounded by the hyoid bone, periosteum and ligament. We encountered a rare case of phlegmon of the oral floor that spread posteroinferiorly along the geniohyoid muscle, forming an abscess in the preepiglottic space.
    A 51-year-old man presented to our clinic with remarkable swelling and pain in the oral floor and submandibular region. He was admitted, treated by incision to promote pus discharge, and given antibiotics. There after, the main symptoms improved rapidly. However, he complained of swallowing pain and dyspnea. Computed tomography revealed an abscess in the posterior region of the hyoid bone. The region is the preepiglottic space, often invaded by laryngeal cancer. The patient was successfully treated because of an accurate diagnosis, and re-incision was done to promote pus discharge from preepiglottic space. When inflammation spreads into the preepiglottic space, clinical findings are often sparse because this region is surrounded by the hyoid bone. Computed tomographic and laryngeal fiberscopic findings are useful in diagnosis.
  • 鈴木 真幸, 大長 珠美, 平野 裕一, 福田 廣志, 橋本 賢二
    2000 年 46 巻 6 号 p. 381-383
    発行日: 2000/06/20
    公開日: 2011/07/25
    ジャーナル フリー
    A mandiblar impacted third molar with exposure of the dental root at the inferior border of the mandible is rare. We describe a case in which the dental root was palpable at the inferior border of the mandible. The patient was a 63-year-old woman with discomfort at the right side of the mandible. A right mandibular impacted third molar was found on examination at a dental clinic in 1992. On presentation to our department on December 21, 1994, radiography showed the presence of a cyst at the crown of the third molar with protrusion of about 1 /4 of the root apex from the lower edge of the mandible. Extraction of the impacted third molar with cystectomy was performed by an intraoral aproach. She has been well since the operation.
  • 小野 貢伸, 藤堂 雅成, 船岡 孝誠, 斎藤 滋夫, 戸塚 靖則, 進藤 正信
    2000 年 46 巻 6 号 p. 384-386
    発行日: 2000/06/20
    公開日: 2011/07/25
    ジャーナル フリー
    Rendu-Osler-Weber disease (hereditary hemorrhagic telangiectasia) is a rare autosomal dominant disorder characterized by abnormal subepithelial vessels in the skin or the respiratory or gastrointestinal mucosa. We report a case of Rendu-Osler-Weber disease with manifestations in the oral mucosa. A 56-year-old woman visited Hokkaido University Dental Hospital because of blood oozing from the maxillary gingiva. Frequent epistaxis was included in her medical history. The patient's father and brother had died of cerebral hemorrhage, and her father and grandmother had suffered from freqent epistaxis. Telangiectases were observed on the skin of the neck. Many angiomatoid lesions were observed on the lower lip, tongue, and buccal mucosa. Histologically, a number of blood vessels were seen in the subepithelial layer of a biopsy specimen of a gingival lesion. The vessels were dilated and were covered with flattened endothelial cells. The clinical and histologic findings were consistent with the diagnosis of Rendu-Osler-Weber disease.
  • 中村 友保, 加納 欣徳, 内田 和雄, 佐藤 雅美, 石井 興, 長縄 吉幸
    2000 年 46 巻 6 号 p. 387-389
    発行日: 2000/06/20
    公開日: 2011/07/25
    ジャーナル フリー
    We report a case of ectopic thyroid at the base of the tongue and submental region. The patient was a 30-year-old man. He had masses in the submental region (45 × 35mm) and the base of the tongue (30 × 30mm). A123I-scintillation scan showed activity in these regions, with no activity in the normal thyroid region. Tumor size decreased gradually in response to treatment with thyroid hormone. Ectopic thyroid is one disease that oral surgeons should include in the differential diagnosis of masses arising in the tongue and cervical region.
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