日本口腔外科学会雑誌
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
48 巻, 5 号
選択された号の論文の13件中1~13を表示しています
  • 鵜澤 成一, 宮本 亮三, 中久木 康一, 根岸 明秀, 鵜澤 祐貴子, 天笠 光雄
    2002 年 48 巻 5 号 p. 245-251
    発行日: 2002/05/20
    公開日: 2011/04/22
    ジャーナル フリー
    Amplification ofthe cyclin D 1gene on chromosome 11q13 frequently occurs in head and neck squamous cell carcinomas (SCCs), including oral cancer, suggesting that abnormalities of this gene may play an important role in the genesis or progression of oral SCCs and serve as an important biological marker indicating a poor prognosis. We investigated amplification of thecyclin D 1gene by fluorescencein situhybridization (FISH) of specimens obtained by fine-needle aspiration biopsy of 20 primary oral SCCs. Amplification of cyclinD 1was detected in 6 (30%) of 20 SCCs of the oral cavity and was more frequently found in patients with a poor outcome (p=0.014). These results confirm that amplification of this gene may contribute to the development of oral SCCs. Analysis of amplification of the cyclinD 1gene by FISH in tissues obtained by fine-needle biopsy may be a rapid and useful method for predicting outcome in patients with oral SCCs.
  • 宮手 浩樹, 横田 光正, 工藤 啓吾, 佐藤 和朗, 三浦 廣行, 水城 春美
    2002 年 48 巻 5 号 p. 252-256
    発行日: 2002/05/20
    公開日: 2011/04/22
    ジャーナル フリー
    Neurosensory function in the mental nerve region of 24 patients who had undergone intraoral inverted L ramus and sagittal splitting ramus osteotomy was assessed by evaluating light touch perception. Neuropathy was present in 67% of the 48 mental nerves examined. The incidence and recovery period of neuropathy on the side undergoing inverted L ramus osteotomy were similar to those on the side undergoing sagittal splitting ramus osteotomy. Our results suggest that dissection of the periosteum around the mandibular foramen might be a main cause of neurosensory deficits of the mental nerve after mandibular osteotomy.
  • 米本 嘉憲, 中山 康弘
    2002 年 48 巻 5 号 p. 257-259
    発行日: 2002/05/20
    公開日: 2011/04/22
    ジャーナル フリー
    Mucosa-associated lymphoid tissue (MALT) lymphoma is an extranodal low-grade lymphoma found mainly in the stomach. It rarely occurs in the oral cavity. We report a case of this tumor in the palate.
    The patient was a 74-year-old woman with a painless swelling of the hard palate. The tumor, measuring 18×15 mm, was located in the center of the hard palate. The tumor was surgically removed. Histologically, the tumor was composed of centrocyte-like cells that showed a positive reaction for L26. The pathological diagnosis was MALT lymphoma. About 4 months after the operation, the tumor recurred in the soft palate, and chemotherapy and radiation therapy were given. Subsequently, the tumor disappeared. One year has passed since treatment, and there is no evidence of recurrence.
  • 関谷 亮, 太田 嘉英, 青木 隆幸, 飯田 政弘, 宮坂 宗男, 槻木 恵一
    2002 年 48 巻 5 号 p. 260-263
    発行日: 2002/05/20
    公開日: 2011/04/22
    ジャーナル フリー
    Carcinosarcoma originating in the salivary glands is rare, accounting for less than 1% of all malignant salivary gland tumors. We report a rare case of carcinosarcoma of the palatal minor salivary gland with fibrous dysplasia of bone. A 20 year-old man presented with a swelling on the palate. A detailed computed tomographic (CT) examination revealed that a tumor occupying the right maxillary sinus had destroyed the maxilla. The tumor was growing rapidly. It was histopathologically diagnosed as carcinoma in pleomorphic adenoma (carcinosarcoma type) on examination of biopsy specimens. The patient was treated surgically (total maxillectomy). Histopathological examination of the resected specimens confi rmed the diagnosis of carcinosarcoma with fibrous dysplasia of bone. No invasion of tumor cells was noted at the surgical margins, but local recurrence occurred 4 months after operation. The tumor invaded the brain, and the patient died 3 months after local recurrence. Autopsy revealed very extensive growth of the recurrent tumor cells, but no distant metastasis.
  • 佐藤 理恵, 星 秀樹, 杉山 芳樹, 関山 三郎, 武田 泰典
    2002 年 48 巻 5 号 p. 264-267
    発行日: 2002/05/20
    公開日: 2011/04/22
    ジャーナル フリー
    We encountered a case of granular cell tumor in the parotid gland. The patient was a 40-year-old man who consulted our department because of a swelling near the left patotid gland on September 8, 1998. The patient had noticed a mass in the region in January 1998, and consulted our department because the size of the mass had increased since August 1998. On extraoral examination, a mass measuring approximately 20mm in diameter was palpable near the left parotid gland. The mass was mobile and had a hard elastic consistency. No tenderness was present. The mass was enucleated under general anesthesia on November 12. The postoperative course has been uneventful for 2 years 10 months, with no signs of recurrence.
  • 立石 晃, 小川 郁子, 高田 隆, 天野 裕治, 相田 高幸, 福田 仁一
    2002 年 48 巻 5 号 p. 268-271
    発行日: 2002/05/20
    公開日: 2011/04/22
    ジャーナル フリー
    We describe the first case of oncocytic myoepithelioma in Japan. The patient was a 53-year-old woman who had a painless mass on the hard palate. The tumor was surgically removed under general anesthesia. The tumor was encapsulated by fibrous tissue. Histologically, the tumor was composed mainly of epithelioid round or oval myoepithelial cells with abundant eosinophilic fine granular cytoplasm. Immunohistochemical studies revealed positive reactions for S-100 protein, vimentin, and cytokeratin in the tumor cells. In addition, the cytoplasm was intensely stained with antibody to mitochondrial antigen. A final diagnosis of oncocytic myoepithelioma was made. Two years postoperatively, there is no sign of recurrence.
  • 津山 泰彦, 寳田 博, 杵渕 孝雄, 富塚 健, 小村 健, 高戸 毅
    2002 年 48 巻 5 号 p. 272-275
    発行日: 2002/05/20
    公開日: 2011/04/22
    ジャーナル フリー
    Inverted papilloma of the nasal and paranasal sinuses is an uncommon, histopathologically benign neoplasm. However, because this tumor has an aggressive nature and a risk of recurrence, complete resection is essential.
    We report two cases of inverted papilloma of the maxillary sinus. Patient 1 was an 80-year-old man with a tumor of the tongue. Accidentally, computed tomography showed a mass of a different density in the maxillary sinus and nasal cavity. The suspected diagnosis was a tumor of the left maxillary sinus. Inverted papilloma was diagnosed on histopathological examination of a frozen-section biopsy specimen, and the tumor was excised under general anesthesia. The postoperative course was uneventful. However, he died of an other disease 18 months after operation. Patient 2 was a 65-year-old man with left nasal obstruction. Computed tomography showed a mass in the maxillary sinus and nasal cavity. The suspected diagnosis was left maxillary sinusitis. Inverted papilloma was diagnosed on histopathological examination of a frozen-section biopsy specimen, and the tumor was excised under general anesthesia. The postoperative course was uneventful, and there has been no evidence of recurrence.
  • 中村 友保, 片浦 俊久, 織田 元, 鯉江 正人, 神出 敏影, 小牧 完二
    2002 年 48 巻 5 号 p. 276-279
    発行日: 2002/05/20
    公開日: 2011/04/22
    ジャーナル フリー
    We report a case of pleomorphic adenoma with marked calcification.
    A 63-year-old woman had an elastic spherical hard nodule measuring about 20×20mm in diameter at the tail of right parotid gland. A computed tomographic examination showed marked calcification within the clearly demarcated tumor nodule. Histologically, the tumor was composed of pleomorphic adenoma with abundant hyalinized matrix components. Numerous calcium granules were found in the fibrous connective tissues surrounding the tumor and demarcating it from the non-neoplastic atrophic parotid gland. Calcification granules were also associated with the degenerative tumor cells and cell debris. The pathogenesis of calcium deposition in the tumor tissue is briefly discussed.
  • 藤田 耕, 原田 浩之, 生田 稔, 原田 清, 岩佐 俊明, 小村 健
    2002 年 48 巻 5 号 p. 280-283
    発行日: 2002/05/20
    公開日: 2011/04/22
    ジャーナル フリー
    Dermoid cyst is pathologically classified in three types according to cellular components: epidermoid, dermoid, and teratoid. Teratoid cyst contains both epithelial and nonepithelial elements, such as hair follicles, sebaceous and sweat glands, fat, bone, cartilage, muscle, and respiratory tract epithelium. Teratoid cyst rarely arises in the head and neck region. This article describes a massive teratoid cyst arising in the floor of the mouth that included sebaceous glands, sweat glands, and cartilage.
  • 福本 裕, 杉崎 正志, 岩本 昌平, 重松 司朗, 滝川 幸生, 大鶴 洋
    2002 年 48 巻 5 号 p. 284-287
    発行日: 2002/05/20
    公開日: 2011/04/22
    ジャーナル フリー
    We report seven cases of mouth closing disturbance caused by the disc of the temporomandibular joint during the final phase of occlusion. The diagnosis was based on the results of magnetic resonance imaging or arthrographic imaging. Two of the seven patients had posterior disc displacement without reduction, while one had the same condition with reduction and the remaining four had posterior folding of the retrodiscal tissue.
    The patients with posterior disc displacement had a history of luxation, open lock, or both, suggesting that the mouth closing disturbance may have been caused by loosening of the lateral and medial attachments of the disc to the condyle as well as by excessive anterior movement of the condyle. The cases of posterior folding of the retrodiscal tissue were apparently related to anterior disc displacement. This condition, which was similar to the posterior open bite that occurs during anterior repositioning splint treatment for internal derangement, apparently occurred spontaneously.
    An important point in distinguishing between posterior folding of the retrodiscal tissue and posterior disc displacement is whether the patient has a past history of reciprocal clicking.
  • 吉田 美奈, 川上 哲司, 馬場 雅渡, 藤本 昌紀, 桐田 忠昭, 杉村 正仁
    2002 年 48 巻 5 号 p. 288-291
    発行日: 2002/05/20
    公開日: 2011/04/22
    ジャーナル フリー
    Willis'circle occlusion refers to stenosis or occlusion of the internal carotid artery arising from Willis'circle, associated with visible capillaries comprising the collateral circulation.
    The patient was a 27-year-old woman who had previously undergone duraencephalosynangiosis at 17 years of age and extracranial-intracranial bypass surgery at 23 years of age. She was examined at the Department of Oral and Maxillofacial Surgery, Nara Medical University Hospital on January 12, 2000 because of temporomandibular joint (TMJ) pain and limited mouth opening. At presentation, maximum mouth opening was 17mm. We describe the successful treatment of severe pain of the left TMJ and trismus by mobilization of the TMJ.
    The pain caused hyperventilation, cataplexy, and numbness of the hands and feet. Angiography showed that blood flow had improved after the extracranial-intracranial bypass. Conservative treatment was unsuccessful. On March 3, 2000, mobilization of the TMJ was done under general anesthesia. The superficial temporal artery was exposed, and blood flow was managed with by microdoppler technique.
    Postoperatively, the patient's pain resolved, and maximum mouth opening increased significantly from 17mm to 38mm. Forward movement and lateral movement increased to 8mm.
    The improvement on a visual analogue scale was also significant. No complications have occurred. As of 15 months after the operation, the response of Willis' circle occlusion to treatment has been good.
  • 術前後の筋突起の形態的変化
    入佐 弘介, 近藤 壽郎, 大浦 健宏, 高橋 研太朗, 岸田 剛, 伊東 隆利
    2002 年 48 巻 5 号 p. 292-295
    発行日: 2002/05/20
    公開日: 2011/04/22
    ジャーナル フリー
    Bilateral enlargement of the coronoid process of the mandible, associated with limited mouth opening, is rare.
    This report describes a case of bilateral hyperplasia of the mandibular coronoid process in a 13-year-old boy. Trismus was diagnosed on a dental examination at school.
    Panoramic radiography showed that both coronoid processes extended above the zygomatic arch. His maximum mouth opening was 27mm (interincisal distance).
    Coronoidotomy was performed via an intraoral approach under general anesthesia, and continuous mouth-opening training was done after surgery. Thirty-four months after the operation, the maximum interincisal distance was maintained at 44mm. The mandibular coronoid process was remodeled posteriorly to prevent interference with mouth opening.
  • 森寺 邦康, 岸本 裕充, 黒田 純子, 櫻井 一成, 浦出 雅裕
    2002 年 48 巻 5 号 p. 296-299
    発行日: 2002/05/20
    公開日: 2011/04/22
    ジャーナル フリー
    Foreign bodies in the oral and maxillofacial region frequently result from trauma and dental treatment. We describe a foreign body, suspected to be a fish bone, in the submandibular gland. A 63-yearold man had a swelling in the left submandibular region. Computed tomography revealed a radiopaque spot, 1mm in diameter, in the gland. Removal of the submandibular gland was performed. The swelling was found to be a foreign body, not a salivary calculus. The foreign body measured 16×1mm and resembled a needle. How this foreign body entered the submandibular gland was unclear. The clinical course suggested that the foreign body had penetrated into the submandibular gland through the oral mucosa.
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