巻号一覧
53 巻, 4 号
選択された号の論文の7件中1～7を表示しています
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大山 順子, 中村 誠司, 宮田 弘毅, 佐々木 匡理, 川村 英司, 熊丸 渉, 林田 淳之將, 豊嶋 健史, 森山 雅文, 白砂 兼光2007 年 53 巻 4 号 p. 220-227
発行日: 2007/04/20
公開日: 2011/04/22
ジャーナル フリーCevimeline hydrochloride hydrate is an agent with muscarinic agonist activity that is used to treat xerostomia in patients with Sjögren's syndrome (SS). We evaluated the efficacy and safety of cevimeline hydrochloride hydrate for the treatment of xerostomia in 54 patients with SS who received the drug for 3 to 21 months.
Salivary flow rate, objective findings, and subjective symptoms such as “xerostomia”, “decreased saliva”, “increased fluid intake”, and “difficulty in swallowing” were significantly improved by 6 months. Salivary flow rate increased in patients who had mild destruction of salivary glands as assessed by sialography and lip biopsies. Symptoms improved in both patients with mild and severe destruction of salivary glands.
Six patients discontinued treatment within 1 month because of nausea and/or vomiting (3 patients), eruption (2 patients), and pregnancy (1 patient). Sweating, heartburn, swelling of parotid glands, diarrhea, headache, nausea and/or vomiting, constipation, and eruption occurred as side effects in 35.0%, 35.0%, 13.3%, 8.3%, 6.7%, 6.7%, 5.0%, and 3.3% of the patients, respectively. Although sweat persisted, other side effects were controlled by symptomatic treatment or decreasing the dose.
These results showed that cevimeline hydrochloride hydrate is effective for improving the quality of life of patients with SS who have dry mouth.抄録全体を表示PDF形式でダウンロード (1161K) -
中山 周子, 目瀬 浩, 小野 達生, 銅前 昇平, 辻本 紗代子, 佐々木 朗2007 年 53 巻 4 号 p. 228-232
発行日: 2007/04/20
公開日: 2011/04/22
ジャーナル フリーVascular leiomyoma is a benign tumor of smooth muscle that originates in blood vessels and occurs mainly on the limbs. It rarely occurs in the oral cavity. We report a case of vascular leiomyoma arising in the buccal submucosa of a 40-year-old woman. She was referred to our clinic because of a painless mass of the buccal mucosa. The tumor measured about 30×20mm and was well localized. The primary clinical diagnosis was a benign tumor of the buccal submucosa. We performed enucleation of the tumor under general anesthesia.Histopathologically, the tumor was diagnosed as a vascular leiomyoma. The posto erative course has been uneventful after 2 years 10 months.抄録全体を表示PDF形式でダウンロード (3290K) -
日比 弓紀子, 大野 清二, 笹部 衣里, 植田 栄作, 山本 哲也2007 年 53 巻 4 号 p. 233-237
発行日: 2007/04/20
公開日: 2011/04/22
ジャーナル フリーWe report a case of lingual osseous choristoma, a rare benign lesion. A 32-year-old woman was referred to our clinic because of a painless polypous tumor on the posterior part of the dorsum of the tongue. There was an elastic hard mass approximately 5mm in diameter on the left side of the cecal foramen of the tongue. We performed excision of the tumor with the patient under local anesthesia. Histologically, the lesion was a well-circumscribed mass of dense lamellar bone with Haversian canals. The postoperative course was uneventful, with no recurrence for about 18 months. Since 1938, when Muta reported the first case in Japan, 37 cases of oral osseous choristoma have been reported, including 34 arising on the tongue. The clinical findings of lingual osseous choristomas were reviewed, and their pathophysiology was discussed.抄録全体を表示PDF形式でダウンロード (1897K) -
田野 智之, 伊賀 弘起, 茂木 勝美, 吉田 秀夫, 林 良夫, 佐藤 光信2007 年 53 巻 4 号 p. 238-242
発行日: 2007/04/20
公開日: 2011/04/22
ジャーナル フリーAcinic cell carcinoma usually arises in the parotid gland and rarely occurs in the minor salivary glands. We report a case of acinic cell carcinoma of papillary cystic type arising in the buccal mucosa. The patient was a 45-year-old woman who had a painless swelling in the right buccal mucosa. The tumor measured 18×15mm and was elastic hard in consistency. The tumor was excised under local anesthesia. Histologically, the tumor appeared to be encapsulated, and the tumor cells were arranged in papillary and partially microcystic patterns. Immunohistochemical examination showed that the tumor cells were positive for S-100 protein, lysozyme, α-antit rypsin, and AE1/AE3 and partially positive for periodic acid-Schiff (PAS). The histopathological diagnosis was acinic cell carcinoma of papillary cystic type. The postoperative course was uneventful, and there was no evidence of recurrence or metastasis 20 months after operation.抄録全体を表示PDF形式でダウンロード (3515K) -
小川 尊明, 大林 由美子, 岩崎 昭憲, 三宅 実, 長畠 駿一郎2007 年 53 巻 4 号 p. 243-247
発行日: 2007/04/20
公開日: 2011/04/22
ジャーナル フリーBehcet's disease is a systemic, chronic recurrent disease characterized by oral aphtha, genital ulcers, ocular lesions, and arthritic symptoms. Incomplete Behcet's disease lacks these common symptoms. We report a case of incomplete Behcet's disease associated with severe trismus.
The patient was a 39-year-old man. Initially, severe trismus developed, accompanied by swelling of the right cheek anthema-like folliculitis, and pharyngitis. Inflammatory symptoms with fever also occurred.
Treatment for trismus was administered to relieve the main symptoms, and collagen disease specialists conducted medical examinations. Incomplete Behcet's disease was finally diagnosed.
Steroid treatment was extremely effective. After 35 days of steroid treatment, the trismus totally resolved. The anthema-like folliculitis was suggested to be caused by inflammation of the masticatory muscles or temporomandibular joint due to Behcet's disease. It was difficult to diagnose this case as incomplete Behcet's disease.抄録全体を表示PDF形式でダウンロード (3050K) -
重松 正仁, 山下 佳雄, 木戸 淳太, 辻 光弘, 檀上 敦, 後藤 昌昭2007 年 53 巻 4 号 p. 248-252
発行日: 2007/04/20
公開日: 2011/04/22
ジャーナル フリーMucosa-associated lymphoid tissue lymphoma (MALT lymphoma) is a low-grade malignant neoplasm of the lymphoid tissue of the stomach, lung, mammary gland, kidney, liver, thyroid gland, thymus, and salivary gland. Intraoral MALT lymphoma is rare. We describe a case of MALT lymphoma arising in the buccal mucosa.
A 78-year-old man presented with swelling and indolent pain of the buccal mucosa on the left side. Clinical examination revealed a 40mm×45mm elastic soft, movable tumor in the left buccal mucosa. An excision with 10-mm surgical margins was performed to remove the lesion. Histopathologic evaluation of the tumor disclosed a lymphoma with MALT characteristics. However, there was no definitive evidence of MALT lymphoma. Further characterization by gene analysis led to the diagnosis of a MALT lymphoma. As of 11 months postoperatively, the patient remains free of recurrence.抄録全体を表示PDF形式でダウンロード (3296K) -
幾本 英之, 大金 覚, 渡邊 章, 内山 健志, 大畠 仁2007 年 53 巻 4 号 p. 253-256
発行日: 2007/04/20
公開日: 2011/04/22
ジャーナル フリーAt birth, the patient presented with macroglossia, renal/hepatic enlargement, abdominal dropsy, and hypoglycemia and was given a diagnosis of Beckwith-Widemann Syndrome. There were no respiratory complications associated with macroglossia. At the school, his classmates used to make fun of his tongue, because it protruded out of the mouth at all times. Thus, his parents decided to let the patient undergo tongue reduction surgeryfor macroglossia. As compared with the tongue size, the width of the mandibular dental arch was too narrow; difficulty in closing the lips was also present. In August 2002, tongue reduction surgery for macroglossia was performed by the Egyedi-Obwegeser technique under general anesthesia. Tongue protrusion as well as open bite were corrected after surgery. Taste function recovered to normal after 3 months.抄録全体を表示PDF形式でダウンロード (2155K)
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