The purpose of this study is to investigate the difference of the skin blood flow (SBF) reaction to white noise exposure during the follicular phase and the luteal phase. We simultaneously recorded ECG, electroencephalographic (EEG) changes and SBF from 13 premenopausal females with normal menstrual cycles. The beat-to-beat changes o the heart rate (HR), the mean EEG frequency (MF-EEG), the mean EEG amplitude (MA-EEG) and SBF were analyzed. White noise exposure significantly caused an increase in HR, MF-EEG and MA-EEG during the follicular and luteal phases. SBF was significantly decreased by the auditory stimuli during the follicular phase, but not the luteal phase. We suspect that difference of SBF reaction was explained by 1) the change of the tonic vasoconstriction 2) the change of peripheral response, and 3) the pathway or the time course changes of efferent autonomic nervous system.
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