The Japanese Journal of Physiology
Print ISSN : 0021-521X
10 巻, 4 号
選択された号の論文の10件中1~10を表示しています
  • 横井 泰生, 上里 恭一, 桑村 司
    1960 年 10 巻 4 号 p. 351-358
    発行日: 1960年
    公開日: 2011/06/07
    ジャーナル フリー
    A new method of restraining rabbit for the continuous recording of rectal temperature was described. It was possible to obtain an apparently physiological rectal temperature curve over the period of twenty-four hours. Insertion and fixation of the thermometer and restraining of the animal were the chief causes for disturbing body temperature. An easy procedure to avoid the unfavorable effectof these two factors was indicated.
  • 佐藤 明夫
    1960 年 10 巻 4 号 p. 359-373
    発行日: 1960年
    公開日: 2011/06/07
    ジャーナル フリー
    Electrogastrogram was studied on the toad's stomach of which muscle walls consisted exclusively of circular fibers. The results obtained are as follows:
    1) Every automatic contraction of the gastric muscle is always accompanied by the slow action potential both in situ and in isolated strip.
    2) The greater part of the potential which usually precedes the muscle contractionterminates as a rule before the relaxation begins.
    3) The rates of rhythm of the potentials are the same throughout the stomach. When peristaltic waves do exist, some of these basic potentials are associated with them.
    4) For the development of tonic contraction it may be essential that the potentialwaves are conducted over the ring more rapidly than usual.
    5) The gradients of potential and the liability of the pace-maker to occur in the direction from the greater to the lesser curvature are observed across the stomach. 6) Vagosympathetic stimulation will elicit a response pattern characterized by the increase in the magnitude and rate of rhythm of the potentials.
    7) Splanchnic stimulation will elicit two kinds of response patterns, probably. excitatory and inhibitory ones. The former is characterized by increase in the conduction velocity, reversals of the direction of conduction, and increase in the rate of rhythm at times; the latter by decrease in the conductivity and asynchroni-zation of the potentials between respective functional units.
  • 鳥居 鎮夫, 川村 浩
    1960 年 10 巻 4 号 p. 374-384
    発行日: 1960年
    公開日: 2011/06/07
    ジャーナル フリー
    1) The effects of amygdaloid stimulation upon the blood pressure were observed in forty-four unanesthetized, curarized cats.
    2) Simultaneous recording of the blood pressure and electrical activity of the brain were carried out and revealed the existence of close parallelism between the hippocampal electrical activity and blood pressure.
    3) Stimulation of the amygdaloid nucleus, septal region and preoptic region generally caused a fall in blood pressure concomitant with appearance of fast waves in hippocampal record, while stimulation of the posterior hypothalamus produced a rise in blood pressure concomitant with appearance of hippocampal regular slow waves.
    4) It is suggested that, as far as blood pressure is concerned, the electrical activity of the hippocampus appears to be an indicator of the autonomic activity.
  • 高木 貞敬, 渋谷 達明
    1960 年 10 巻 4 号 p. 385-395
    発行日: 1960年
    公開日: 2011/06/07
    ジャーナル フリー
    The activity of the olfactory epithelium was studied in the frog and the toad by means of micro-and macro-electrodes.
    1) Resting potentials of 4 to 16 mV (9.5 mV on the average) were obtained when a micro-electrode impaled the epithelium.
    2) In response to olfactory stimulation, the slow potentials were simultaneously recorded by means of micro-and macro-electrodes. They were found not only at the onset of stimulation, but also at the cessation. Thus, three types, on-, on-offand off-types of responses were found.
    3) The stability of the response types was studied by repetitive application of the same odour. It was found that the response types of the cells in the olfactory epithelium are not stable in the frog and the toad.
    4) The response types obtained by micro-electrode do not always coincide with those recorded by macro-electrode. Moreover, the shapes and the types of the responses obtained by two micro-electrodes set as close as possible are not always the same. It was therefore concluded that there are two or three kinds of elements in the olfactory epithelium which produce the on-and the off-, or the on-, the on-off-and the off-responses.
    5) An electro-positive off-response rarely appeared after a normal electro-negative on-response. It coincides with the off-response found in a kind of fish.
  • 田中 守也, 佐々木 和夫, 深見 安, 千葉 康則
    1960 年 10 巻 4 号 p. 396-402
    発行日: 1960年
    公開日: 2011/06/07
    ジャーナル フリー
    1) The existence, plentifulness and direction of the direct fiber connexions between ipsi-and contralateral acoustic cortical subareas of dog were examined by means of strychnine neuronography.
    2) By local strychninization of MES, direct fiber connexions from MES to the ventral half of ipsilateral PES and AES were disclosed. The more posterior was the strychninized region in MES, the more frequent and marked were the spikes in AES.
    3) Local strychninization of the dorsal half of PES revealed direct fiber connexions only to the ventral half of PES. On the contrary, by local strychninization of the ventral half of PES, direct connexions from there to the dorsal half of PESas well as to MES and AES were found.
    4) By local strychninization of AES, direct connexions from AES to MES andthe third area were found.
    5) The interrelations between the third area and other areas were not clearly confirmed, because local strychninization was not applied to the third area. 6) As to the acoustic areas on both hemispheres direct fiber connexions were found only between homotopic regions.
  • 佐々木 和夫, 並河 昭, 松永 守雄
    1960 年 10 巻 4 号 p. 403-413
    発行日: 1960年
    公開日: 2011/06/07
    ジャーナル フリー
    1) The influence of stimulations of the striate body, internal capsule and pyramidal decussation upon the spinal activity was studied with cats under the slightest degree of Nembutal anesthesia. Intracellular potential recording from lumbaralpha motoneurons, as well as recording of ventral root electrotonic potentials, were performed in association with brain stimulations and sometimes also with dorsal root stimulations.
    2) Stimulation of the caudate nucleus and globus pallidus reduced the size of spikes in the contralateral ventral roots discharged as a monosynaptic reflex by dorsal root stimulation. Striatal stimulation in isolation produced a positive ventral root potential.
    3) Stimulation of the caudate nucleus and globus pallidus induced a train of irregular hyperpolarizing deflections in the membrane potential of the contralateral extensor and flexor motoneurons. These hyperpolarizing deflections, which are considered as IPSP's, abolished a spike discharge in a motoneuron reflexly induced by dorsal root stimulation. Similar, but somewhat less marked changes, with a few exceptional cases of facilitatory effect, were found when putamen was stimulated.
    4) Stimulation of the internal capsule resulted in a facilitated monosynaptic discharge in the contralateral ventral roots. EPSP's and a consequent spike discharge were found by intracellular recording. Sometimes IPSP was recorded prior to EPSP.
    5) EPSP and spike potential in spinal motoneurons were resulted from stimulation of the pyramidal decussation.
    6) Some of the spinal interneurons responded both to dorsal root stimulation and to striated stimulation. Others were found responsive to dorsal root stimulation and stimulation of the internal capsule.
  • 福原 武, 中山 沃, 難波 良司
    1960 年 10 巻 4 号 p. 414-419
    発行日: 1960年
    公開日: 2011/06/07
    ジャーナル フリー
    1) With the small intestine in the dogs anesthetized with morphine and urethane the authors studied the localization of receptors which are concerned with the intestino-intestinal extrinsic and muscular intrinsic reflexes.
    2) Both reflexes are elicited by stretching the longitudinal muscle layer of the small intestine and only this layer, but not by stretching other layers, i.e., the mucosa, submucosa and circular muscle layer not being causative of the reflexes.
    3) It may be presumed that in the extrinsic reflex the longitudinal muscle layer contains the receptors whose cell bodies are located in the spinal ganglion, while in the muscular intrinsic reflex the receptors similar to the extrinsic one, are located in the longitudinal muscle layer but have in AUERBACH'S plexus their cell bodies which in turn are synaptically connected with the inhibitory neurons located in the plexus.
  • 福原 武, 中山 沃, 難波 良司
    1960 年 10 巻 4 号 p. 420-426
    発行日: 1960年
    公開日: 2011/06/07
    ジャーナル フリー
    1) Recording the motility of as well as the fluid transport through the denervated dog's jejunal loop the effects of 5-HT and additionally of some chemical substances upon the intestinal motility were studied.
    2) When 5-HT was applied to the mucosal or serosal surface, the intestinal motility was excited above and inhibited below the stimulated spot. The removal of the villi did not change the responses at all. However, no response was observed after cauterizing the superficial layer of the basal part of the mucosa, tunica propria surrounding the crypts.
    3) The reflex responses did not appear, when the application of 5-HT to the mucosal surface was preceded by that of C6 or tetraethylammonium bromide.
    4) After cocainization of the mucosal surface the responses described above were not produced by stroking, or applying HCl to the mucosa, whereas they were rarely so by applying 5-HT to the same spot as before.
    5) When 5-HT was repeatedly applied at a short interval of time to the one and the same spot of the mucosa, the responses grew weaker and weaker, disappearing finally (5-HT insensitivity). In-this case, however, stroking, or applying HCl to the mucosa produced the responses.
    6) 5-HT acted upon the intestine at first to allow the fluid transport through it to be retarded and then to become insensitive to the subsequent application of 5-HT; in this instance HCl solution, however, produces a remarkable retardation of flow.
    7) From the results described above it may be said that 5-HT acts upon the peripheral nerve endings which are presumed to be distributed to the superficial layer of the basal part of the mucosa, tunica propria surrounding the crypts.
    8) Phenyldiguanide (PDG), as far as the mucosal intrinsic reflex is concerned, behaves exactly identical with 5-HT.
  • 後藤 昌義
    1960 年 10 巻 4 号 p. 427-435
    発行日: 1960年
    公開日: 2011/06/07
    ジャーナル フリー
    1) The transmembrane potentials and the tension were recorded from strips of the rat uterus in the later middle period of pregnancy to elucidate the mechanism of action of oxytocin.
    2) The spontaneous contraction of the uterine muscle was very irregular and weak in this period. Application of pitocin to the muscle, however, caused first a strong and tonic contraction and next a series of rhythmical contractions. The tonic contraction was accompanied not only with an increase in the muscle tonus but also with a long series of tetanic discharges.
    3) The maximum frequency of discharge increased under the effect of pitocin given in a low concentration, but decreased in a high concentration despite a strong tension development. In the latter condition all penetrated cells discharged syntonically in regular rhythm, and pitocin seems to strengthen the mutual and functional connection between each two myometrial cells.
    4) Pitocin caused a decrease in size of both resting and active membrane potentials. The decrease may be attributable partly to the tension development on the muscle, but partly to the direct action of pitocin on the membrane, because the membrane potentials decreased even in a muscle unfixed and kept isotonic.
    5) The action potentials appeared rather flat in shape under the effect of pitocin, but the spikes became uniform both in height and shape. The action potentials recorded after the removal of pitocin were, on the other hand, very irregular in shape, height and rhythm, including a twin or a triplet spike occasionally between discharges. These facts also support the view that pitocin acts strongly on the muscle cells by strengthening their functional bindings.
  • 中 研一, 猪間 その, 小杉 要治, 董 志文
    1960 年 10 巻 4 号 p. 436-442
    発行日: 1960年
    公開日: 2011/06/07
    ジャーナル フリー
    1) Methods for obtaining big action potentials from the frog retina were studied.
    2) From superficial layers of the retina several types of spike potentials were recorded intracellularly. The spike potentials obtained from the deepest layer were superimposed on an ERG-like slow potential.
    3) From a depth about 40 micra posterior to the layers giving the spike activity, a large negative potential resembling the S-potential in the fish retina was recorded.
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