Effects of physical thrapies on the stiffened joints have not clearly illustrated. They practically have been carried out on the base of experiences of doctors and physical therapists.
In order to elucidate the effects of some physical therapies on the stiffened joints, the following temperatures of the joint structures in 5 cases with normal and stiffened knee joints were measured by use of an electron thermometer.
1) the surface temperature of the skin (ST)
2) restoring time at cold burden test (RT)
3) muscular temperature (MT)
4) intra-articular temperature (AT)
Physical therapies, active movement of the lower extremity and manual massage, were carried out for 10 minutes. Thereafter, these temperatures were measured every 5 minutes for 30-45 minutes.
The results obtained were as follows:
1) Surface temperature of the skin (ST)
By active movement, elevation of ST was slight in both normal and affected sides. But, these were gradually descended with the lapse of time. On the contrary, by manual massage, greater elevation of ST and its long duration were proved in both sides.
2) Restoring time at cold burden test (RT)
By manual massage RT was not altered or delayed a little. But, shortening of RT was caused by active movement. This shortening suggests that by active movement blood circulation in the lower extremity is promoted.
3) Muscular temperature (MT)
By active movement, elevation of MT at affected side was slight. After manual massage, however, marked elevation in both sides was shown. Particularly in affected side, its elevation continued for a long time.
4) Intra-articular temperature (AT)
After active movement, marked changes of AT were not detected. By manual massage, 1.5°-2°C elevation of AT was maintained for a long time.
From these experimental and clinical results above-described, it was summarized that blood circulation around the joints was accelerated by active movement. From these points of view, it was concluded that active movement was superior to manual massage as a physical therapy for the stiffened joint.

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In treatment of the patient with cerebral palsy, training is most important. The appearance of a medical compound from which we can expect progress in the training effect was very desirable.
Cercine was given to seventeen patients with cerebral palsy of the spastic type and mixed type with athetosis which have strong muscle spasmus. Of the seventeen patients nine were of spastic type and eight were of mixed type with athetosis.
Excellent result was obtained in fifteen patients.
Decrease of muscle spasmus and opisthotonus, possibility of turning over in bed and maintenance of sitting, improvement of walking were aquired. Namely muscle relaxation was remarkable.
In mixed type with athetosis in which muscle spasmus was light, results were not effective.
Dose was very different owing to symptom and individual differences.
Dose of one day is generally as follows:
infants: 1-2mg.
child: 2-6mg.
adolescent: 6-10mg.
Treatment of cerebral palsy needs a very long period of time as compare with general orthopaedic diseases.
Effects of cercine are muscle relaxation, anticonvulsion and sedative action. These combined actions have many more enhanced effects.
The Use of cercine has great significance for the treatment of cerebral palsy.
In the future, it is believed that cercine will fulfils an important part in the treatment of the cerebral palsy.

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