日本胸部疾患学会雑誌
Online ISSN : 1883-471X
Print ISSN : 0301-1542
ISSN-L : 0301-1542
17 巻, 7 号
選択された号の論文の7件中1~7を表示しています
  • 北浦 三郎, 南条 邦夫, 加藤 錠一, 森 幸三, 菅 栄, 永坂 博彦, 加藤 政仁, 山本 俊幸, 武内 俊彦
    1979 年 17 巻 7 号 p. 383-389
    発行日: 1979/07/25
    公開日: 2010/02/23
    ジャーナル フリー
    We used bronchofiberscopy in lung abscess for aspiration of bronchial secretions and lavage with saline in lung abscess cases.
    The bronchofiberscope was introduced orally under topical anesthesia with 4% Xylocain. After the bronchofiberscope was inserted into the appropriate bronchus, bronchial brushing, suction of secretions, and lavage with saline were performed, followed immediately by aspiration with a vacuum pump. Finally we infused antibiotics into the bronchus. Postural and vibration drainage were performed after this procedure.
    19 patients ranging in age from 28 to 86 with a diagnosis of lung abscess were treated by this procedure. In 13 (68%) of the 19 patients clinical and roentogenologic improvements were obtained by this procedure. The reduction in the period of illness with this method is evident. The strain the patients is so low that even elderly patients can receive this therapy. Greater effectiveness is obtained if applied at an early stage after the onset but. It would not be effective in cases with peripheral localization of the affected region. These results indicate that the bronchofiberscope is effective in initiating drainage of lung abscess.
  • 広瀬 俊雄, 佐藤 茂, 井上 洋西, 生方 正, 菊地 喜博, 滝島 任
    1979 年 17 巻 7 号 p. 390-401
    発行日: 1979/07/25
    公開日: 2010/02/23
    ジャーナル フリー
    The effects of ambient levels of O3 on rabbits were studied in terms of combined functional and morphological parameters. First, we measured closing volume and lung volumes in pentobarbitalized adult rabbits by use of the single breath oxygen test and then observed morphological changes in the rabbit's lungs with light microscopy and scanning and transmission electron microscopy. Rabbits were exposed to O3 ranging from 0.46 to 1.09ppm for 12 hours and were examined with regard to both parameters on 6 hours, the 1st, 3rd and 7th day after exposure.
    Pathologic changes in rabbits examined 6 hours after O3 exposure were most marked in the area from the terminal bronchioles to the alveolar ducts. Characteristic changes were narrowing of the bronchiolar lumen by infiltrating mononuclear cells and desquamated bronchiolar epithelial cells, “loss of cilia”, surface roughness of cilia and flatness of the Clara cells with ditches. The longer the interval of recovery was, the less prominent the pathologic changes. On the 7th day pathologic changes also returned to near normal morphologically.
    Mean CV% value increased significantly in rabbits on 6 hours and 1 day after exposure compared with the control animals which were not exposed to O3, and returned to near normal on the 7th day. In conclusion, there was a close correlation between pathologic alterations in bronchioles and changes of closing volume caused by O3 exposure.
  • 大野 正人, 中田 肇, 木本 龍也, 西谷 弘, 松浦 啓一
    1979 年 17 巻 7 号 p. 402-408
    発行日: 1979/07/25
    公開日: 2010/02/23
    ジャーナル フリー
    Chest Roentgenographs of 16 autopsied malignant lymphomas which had bilateral diffuse lung abnormalities within six days before death, were correlated with pathological findings.
    Chest roentgenographic findings were classified into six groups; (1) miliary, (2) nodular, (3) linear or reticular, (4) opaque (alveolar), (5) opaque (non-alveolar), and (6) mixed densities.
    1) Most of the cases had opaque densities (Type 4 and 5) on chest X-ray.
    2) Pathologically, pulmonary lymphomas were noted in 10 cases and 6 cases were free from lymphoma cells. Various non-tumorous complications were associated in the majority of cases.
    3) Lymphomatous infiltration was relatively infrequent in cases with pure opaque alveolar pattern.
    4) Nodular densities did not reflect any specific pathological process. Roentgenographic distinction between benign and malignant processes was impossible.
  • 黒田 孝井, 森本 雅巳, 志田 寛, 野口 修, 小沢 克良, 丸山 雄造
    1979 年 17 巻 7 号 p. 409-414
    発行日: 1979/07/25
    公開日: 2010/02/23
    ジャーナル フリー
    Endobronchial hamartoma is an extremely rare disease and only a few cases have been reported in Japan.
    The first case was a 46 year old male suspected of early lung cancer in the hilar region who recieved right middle and lower lobe lobectomy. The secoud case was also male, 54 years old, and underwent right lower lobectomy on a diagnosis of bronchial adenoma. In the gross examination of both cases, a bean-sized, firm, smooth polypoid lesion was found in the mucosa of the orifice of B6. Microscopically, in both cases the tumors were composed of submucosal adenochondromatous masses which were covered with regular ciliated columnal epithelium and contained bronchial glands with edematous stroma in the center of the mass.
  • 福嶋 和文, 石見 寿康, 筒井 大八, 森岡 茂治, 西村 良秋, 田中 立夫
    1979 年 17 巻 7 号 p. 415-420
    発行日: 1979/07/25
    公開日: 2010/02/23
    ジャーナル フリー
    Pulmonary involvement in multiple myeloma is very uncommon. In the case to be presented, extraosseous pleuropulmonary involvement was a dominant feature.
    A 69-year-old man, a farmer, was admitted to our hospital with a chief complaint of anorexia on August 21.1978. A test for Bence Jones protein was positive. The erythrocyte sedimentation rate was 66mm/hr. The serum total protein was 8.1g/dl and a monoclonal pattern was observed in γ-globulin area. X-ray films of the bones showed generalized osteoporosis and punched-out lesions in the skull. X-ray films of the chest revealed a mass with an ill-defined margin in the right hilar region, measuring 3×3.5cm in its greatest dimensions, extrapleural signs associated with pleural fluid in the left lung field, and also polycystic shadows in the left lower lung field. A lot of myeloma cells and M-protein were revealed in the pleural fluid. The patient was diagnosed as IgG, λ-type multiple myeloma on immunoelectrophoretic examination of the serum, urine, and pleural fluid. Treatment with corticosteroids and cyclophosphamide was quite ineffective and he died in 2 months.
  • 早川 正徳, 小山 治, 福原 正博, 大西 一男, 日並 史成, 斉藤 清治, 豊川 清子, 足立 和彦, 高雄 延之, 種本 基一郎
    1979 年 17 巻 7 号 p. 421-425
    発行日: 1979/07/25
    公開日: 2010/02/23
    ジャーナル フリー
    A case of occupational asthma due to polyurethane was presented. A 56 year old male had been engaged in spraying polyurethane for one year. He developed dyspnea and cough while working six months before. Physical examinations on admission revealed rhonchi and rough breathing sounds. The pulmonary function tests showed an obstructive pattern. After dyspnea disappeared, inhalation provocation tests by polyurethane were made.
    When the hardner, the thinner and the paint are mixed together, polyadditive reactions occur between the hardner and the thinner, and a polymer is formed. Although provocation tests by various combinations of materials were made, an asthmatic attack was induced only when the above three materials were mixed together in a spray and inhaled by the patient. Therefore, polyurethane polymer was considered to be the allergen.
  • 植木 幸二, 瀬ノ口 頼久, 乗松 克政
    1979 年 17 巻 7 号 p. 427-432
    発行日: 1979/07/25
    公開日: 2010/02/23
    ジャーナル フリー
    45歳男性, 集団検診にて右縦隔部の腫瘤様陰影を指摘さる, X線学的にこの陰影は拡大せる“azygos knob”と考えられた為, 静脈造影を施行. 通常の下大静脈は認められず, 拡大した奇静脈を経て上大静脈より右房へと造影剤の流入を認め, 奇静脈代行型の下大静脈欠損症の確診を得た. 尚, 肝静脈は直接右房に連絡していた.
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