Irradiation by low output semiconductor laser beam according to the method using “Koshi” by acupuncture at an irradiation site of lesions and a contralateral site of healthy region as a control resulted in expansion of the mobility range of neck, shoulder and arm syndromes. It was effective for motion pains of arm joint or joint pains of metacarpophalangeal joint and also effective for lumbago and neuralgia. It did not easily improve the effects on cervical motion pain and knee joint pain. In all 29 cases (consisting of 6 men and 23 women aging 30 to 75 years), 18 were effective: 3 of 3 cases with neck, shoulder and arm syndrome, 1 of 4 cases with cervical movement pains, 1 of 2 cases with arm joint pains, 2 of 2 cases with back pains, 6 of 8 cases with lumbago, 1 of 5 cases with knee joint pains, 2 of 2 cases with neuralgia, 1 of 1 case with foot joint pains, and 1 of 1 case with metacarpophalangeal joint pains, 9 moderate: 3 of 4 cases with cervical motion pains, 1 of 2 cases with arm joint pains, 1 of 8 cases with lumbago, 3 of 5 cases with knee joint pains, and 1 of 1 case with elbow joint pains, and 2 poor: 1 of 8 cases with lumbago and 1 of 5 cases with knee joint pains. Thus laser beam effectiveness was confirmed.

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Semiconductor laser beams were irradiated through a puncture orifice in response to several symptoms accompaning slight gastritis and enteritis encountered in daily practice. Effectiveness was confirmed by the following results: 1) 3 cases of nausea accompanied with acute gastritis resulted in improvement in all 3 cases; 2) 6 cases of sense of stomach heaviness without gastritis more improved in 5 cases and poor in 1 case; 3) 6 cases of stomachache accompanied with gastritis were improved in 4 cases with moderate effectiveness in 2 cases; 4) 2 cases of a sense of abdominal bloating and abdominal pain accompanied with enteritis were both improved; 5) 6 cases of nausea, sense of stomach heaviness, stomachache, and abdominal pain accompanied with gastritis and enteritis were improved in 5 cases and poor in 1 case; 6) these effects appeared within 15 to 30min after irradiation; 7) the effectiveness of semiconductor laser beam could be confirmed as it resulted in improvement in 19 cases, moderate in 2, and poor in 2 out of a total of 23 cases with gastrointestinal symptoms; 8) no abverse reaction was observed in any case.

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I'll report that I perceived the change to deep body temperature, blood pressure, volume pulse wave, cinnamic acid parcial pulse and pulse rate as a result of having effect to the blood stream of the whole body by acupuncture stimulation.
By acupuncture stimulation deep body temperature, although there is unsettled descending tendency in soles and ascending one in palms, both the difference between the right and left tended to decrease.
Both the highest blood pressure and the lowest blood one indicated ascending tendency.
When volume pulse wave reached at 74% of all cases of illness, claudication ratio became smaller.
Cinnamic acid partial pressure increased alike on an average 7.5mmHg.
The pulse rate decreased at 95% of all cases of illness.
While deep body temperature, blood pressure, volume pulse and pulse rate are changing towards minus, only the ascending tendency of cinnamic acid partial pressure indicates that it will have effect of getting a living body back a harmonious condition.

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we have studied changes in both cardiac performance and the peripheral circulation in order to investigate cardiovascular influences due to electro-acupuncture stimulation (EAP) at the two meridian acupoint (Pericadium and Large Intistine) related to cardiovascular activities.
1) No significant changes were seen in blood pressure and heart rate after EAP at NAIKANGEKIMON (P4-6). However, the impedanve SV and CO were increased markedly with the same consition of EAP.
2) As for stroke volume and cardiac output, EAP had greater effects than dopamine 4μg/kg/min and dobutamine 8μg/kg/min and had almost the same effect as Haemaccel 2ml/kg.
3) No significant changes were seen in blood gas tensions or electrolytes but plasma colloidal osmotic pressure tended to decrease.
4) After EAP at GOKOKU-TESANRI (LI4-10), radial artery was Belated: and the constrictive response of radial artery under the influence of autonomic nerves remained as normal.
5) Sequential changes capillary blood flow were increased as same as the radial artery flow by the effect of EAP.
6) Concerning EAP effects on cardiac performance and peripheral blood circulation EAP at P4-6 LI4-10 induced significant changes but at non-acupoint had no significant effects.

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Radioisotope renography, which is a technique for extracorporeal examination of kidney utilizing radionuclides, can provide the data of renal dynamics such as blood flow and excretion of urine about individual kidney. Since this technique allowes simple and noninvasive examination of renal functions, it is now commonly used clinically.
The present study was designed to elucidate a relationship between renal function and meridian point by using radioisotope renography. In this paper the effect of acupuncture applied placing-needle wlth low frequency wave to Shenshu (UB-23) of the urinary bladder channel of foot-taiyang on renal function, especially excretion of urine, was observed.
It was found that urinary elimination of radioisotope after acupuncture increased, although no marked change was noted on the pattern of renogram curve.

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We investgated the effect of electric acupuncture on peripheral T lymphocyte subset from normal individuals, analysed by laser flow cytometric system with monoclonal antibodies for human T lymphocyte subset.
OKT3⁺ cells (peripheral T cells) and OKT4⁺ cells (helper/inducer cells) did not show any changes after electric acupuncture. OKT8⁺ cells (suprressor/cytotoxic T cells), however, OKT11⁺ cells (E rosette positive T cells) and Leu7⁺ cells (natural killer cells) increased and Leu11⁺ cells (another population of natural killer cells) decreased after electric acupuncture.
These changes of peripheral T lymphocyte subsets would suggest that electric acupuncture effects human immune system.

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Using 83 assumed arthrosis deformans of the knee patients as subjects we conducted a clinical study of acupuncture therapy adding cross-insertion and twisting techniques and examined the therapeutic results in a total of 72 cases, omitting cases in which treatment was discontinued.
Treatment was divided into general treatment which was administered in all cases and classified treatment according to the specific area of pain. Results were evaluated by 4 ranks-cure, improvement, no change and aggravation of symptoms, according to the rate of improvement in pain and test results. These results indicated either cure or improvement in 67 cases (93%), that is in a large majority of the cases an improvement of symptoms was obtained with acupuncture therapy. Looking at the number of treatments, results improved respectively with the greater number of treatments. Therapeutic results were about the same in all age groups. Treatment over an extended period is necessary in cases in which the painful area feels hot upon touch however it became clear that if treatment is continued good results are obtainable.

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The positional relation between the point Jingei and the bifurcation of the common carotid artery was investigated with dissection of the neck after inserting a needle into the bilateral Jingei, using nineteen Japanese cadavers. We determined first the position of the point Futotsu as a point in the sternocleidomastoid lying about 10cm lateral to the laryngeal prominence along the neck wrinkle, and defined the location of Jingei in the cadavers as the mid-point between the laryngeal prominence and Futotsu mentioned above. The common carotid artery shows a dilatation, termed the carotid sinus, at its point of division into the external and internal carotid arteries. The needle did not prick the carotid sinus in all of the thirty-eight cases of insertion; it pricked the common carotid artery at a lower level than the carotid sinus in four of these cases, and in the other cases the needle did not prick the vessel, but rather a portion of the neck medial to the vessel at the lower level, similarly as in the former cases. The points of division of the common carotid arteries of the cadavers dissected were all located at a considerably higher level than the laryngeal prominence; the average level was 32.8mm higher than the prominence on the left, with maximum and minimum values of 52 and 11mm, respectively, and 29.9mm upper on the right (maximum and minimum values: 45 and 8mm). Furthermore, it was suggested that the insertion of a needle at the level of the hyoid bone has a higher possibility of reaching the carotid sinus than that at the level of the laryngeal prominence in acupuncture of the sinus.

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I. Purpose:
Individual differences in effects of acupunctual anesthesia during uterine endometrial biopsy were tested by means of the modified methods of Cornell Medical Index (CMI-test).
II. Methods:
Two hundred forty eight patients were examined for this tests for three years since Dec. 1982. Needles for acupuncture were applied into Ashisanri (Zusanli) and Saninko (Sanyinjiao.) After careful recognition of sufficient Tokkuki (The chih) following acupuncture, stick-points of needles were lead to Neurometer NAJ.
After approximately 30 minutes of electrical induction, biopsical operation were started. Anesthetical effectiveness of acupuncture were confirmed as follows:
(1) During biopsy, facial features what to speak, body movements, sweating, and condition of anesthesia of patients were observed and checked on the specialized score table in order from zero to 28 points. Acquired points less than 11 were indicated as effective anesthesia.
(2) Following operation the inquires about grade of pain feeling during biopsical procedures were carried out and then they were classified into four ranks: no pain, slight pain. moderate pain and strong one. The last two were considered as no effective.
(3) In addition to the above mentioned two, CMI-test was performed.
III. Results:
From score points; The effectiveness was as follows, normal type group, 79%; subnormal, 77%; breaking down of autonomic nerve system, 44%; neurosis, 86%; psychosomatic type, 68%.
On the other hand, from inquires the following were obtained: normal 65%; subnormal 50%; autonomic nervous disorder, 19%; neurosis, 41% and psychosomatic type, 37%.
There is no critical differences between both results from score points and inquiry system.
It is concluded from results that acupunctual anethesia were not much effective in patients who have disorders of autonomic nervous system and psychosomatic system, while much effective in patients with neurosis.

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Effects of moxibustion on the jaw-opening reflex (JOR) were examined in lightly anesthetized rats. The evoked EMGs of digastric muscle elicited by tooth pulp stimulation were clearly suppressed for 2-3min by the moxibustion applied to the hair-removed skin. The suppressive effects of moxibustion on the JOR indicated some regional differences. The most effective region was the contralateral fore-arm, and a slightly less effective regions were the ipsilateral face, ipsilateral fore-arm and contralateral hind-leg. The difference of the effectiveness on JOR suppression between the acupuncture point and non-acupuncture point was not apparent.
These results suggest that the polymodal receptor, which is undoubtly activated by moxibustion, participates in the peripheral process of the induction of analgesic effect.

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[in Japanese]

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Which part of the cerebral cortex does acupuncture stimulation project on? Where are pain impluses inhibited? These problems are discussed here.
The pain pathway begins at the posterior horn of the spinal cord, where pain impulses could be inhibited. Then the impulses are inhibited in the reticular formation of the brainstem and at the synaptic connection in the thalamus. They are also inhibited in the limbic system and in the hypothalamus strongly. The sensory center (pain center) in the cerebral cortex associates the pain signals and then efferently inhibits the posterior horn through the pyramidal and extrapyramidal tract.
It is thought that pain is repeatedly inhibited in the hierarchical loop formed of the spinal cord, the reticular formation of the brainstem, the thalamus, the limbic system, the central region of the cerebral as a center, the basal ganglia, the reticular formation and the spinal cord.

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