The gynecologic tumor clinic of Kitasato University Hospital has registered 1, 000 patients during three year period since founded on July 26, 1971. Statistical analyses with special reference to cytologic features were performed on these registered patients. One hundred and fourty-seven cases, 15% of the registered, were found to be malignant including 128 with carcinoma of the cervix (86.4%), six with corpus cancer and nine with metastatic cancer of extra-genital origin. CIS and stage Ia revealed 42, 32.8% of the cervical carcinomas, and 10.8% of the regitered were dysplasias. The malignancy rate of each age group showed less than 10% in 26-40 years of age and increased gradually up to more than 50% in those above 61 years.The average ages of severe dysplasia, CIS, stage Ia, and stage Ib and above were chronolo gically elevated to be 38.6, 39.8, 44.5 and 57.0 respe ctively.
The cytologic diagnoses were made to be negative in 76.9%, suspicious in 10.6% and positive in 12.5%. There was no false negative case in cervical carcino mas. Seven cases (30.4%) of CIS, however, were diagnosed as class M a. The retrospective analysis revea-led that malignancy was ruled out in two cases, ap-parent carcinoma cells were missed in two and seve-re dysplasia rather than CIS must have been diagno sed in three. The cytologic features of the metastatic carcinomas of the stomach (3 cases), the bladder (2 cases) and the caecum (one case) were explained. False positive rate of smear tests was 0.2%.There includes a case of reparatory process which had been diagnosed as adenocarcinoma.
Abnormal findings of colposcopy revealed 50% of squamous metaplasia, approximately 70% of each dys-plasia, 90.9% of CIS, 89.5% of stage Ia and 97.5% of stage Ib and above.Occurrences of L, F and/or G in slight, moderate and severe dysplasias, CIS and tage Ia appeared 67.6%, 68.0%, 75.0%, 78.4% and 84.2% respectively. AU was malignant in 20% when found alone and in 70% when combined with L, F or G. The malignancy rates of L, F, G and AU were 30.9%, 24.2%, 26.9% and 43.6% respectively.
CIS and stage Ia were diagnosed correctly in 90% with either smear or colposcopy, however each cove red another in 10%, and colposcopy had its priority when diagnoses lowered the degree of dysplasias. Preoperative diagnoses using the combination of smear, colposcopy and colposcopyguided biopsy were under in one rank in 33.3% of severe dysplasias, 22.2% of CIS and 20% of stage Ia.
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