A 74-year-old wolnan was admitted becase of a large amount of ascites. The patient also pointed out the presence of a breast tumor. Aspiration cytology of the breast tumor and a cytology exalnination of the ascites were pcrformed. Cytologicaly, the tumor cells in the ascites were small. sized and uniform-In celis with a low N/C ratio, the chromatin pat. tern was fine and uniform. ICL was observed in the cytoplasm. The tulnor cells were individually dispersed. The cytological findings strongly suggested that these cells were reactive mesothelial cells. Histologlcally, the breast tumor was diagnosed as an invasive lobular carcinoma that was positive for CA19-9. The peritoneum biopsy was diagnosed as a metastasis of the invasive lobular carcinoma of the breast. Thus, the cells which had been regarded as reactivc mesothelial cells were in fact adenocarcinoma cells.
We report a case of an extramedullary relapse of acute myelogenous leukemia [M2 t (8; 21)] in the parotid gland and parapharyngeal space of a 50-year-old male. A Papanicolaou stain, revealed scattered small blasts with enlarged. nuclei. The blast-like cells were difficult to definitively diagnose by Papanicolaou stain. but the clinical findings enabled a diagnosis of the extramedullary spreading of acute leukemia cells to be confirmed using immunohistochemistry for peroxidase as well as May Giemsa staining. The possibility of extramedullary extensions or relapses should be kept in mind during the cytological examination of solid mass lesions in patients undergoing chemotherapy for acute myelogenous leukemia.
We report a case of chromophobe renal cell carcinoma in a 39-year-old woman. The squash cytological specimen showed tumor cell clusters composed of large-sized polygonal cells with a low nucleocytoplasmic ratio. The cytoplasm was characteristically cloudy and reticular or eosinophilic granular. Occasionally, a perinuclear halo was visible. The nuclei were spherical and contained small nucleoli. The unique clinicopathological and molecular biological characteristics of chromophobe renal cell carcinoma make cytology a very useful tool for its correct diagnosis.
We report a case of fetal abdominal cyst that was prenatally diagnosed using aspiration cytology. An abdominal cyst with a diameter of 6 cm was detected by ultrasonography in a 30-weekold female fetus in a twin pregnancy. Transitional cells were detected in a aspiration cytology specimen from the dilated ureter. The fetus was delivered at 34-weeks by Cesarean section, and she is presently alive, although she has some urogenital anomalies. Cytology is a useful method for prenatal diagnosis.