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Volume 45, Issue 6
Displaying 1-8 of 8 articles from this issue
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Comparison of cytotechnologists and medical technologistsSetsuo SUGISHIMA, Motoko KOREMATSU, Hiroe OIKAWA, Tsunehito IWASAKI, K ...2006 Volume 45 Issue 6 Pages 313-317
Published: November 22, 2006
Released on J-STAGE: November 08, 2011
JOURNAL FREE ACCESSObjective: We determinated physical and mental symptoms in cytotechnologists doing microscopic work. Study.
Design: Subjects numbere 201-102 cytotechnologists (men: 49, women: 53) and 99 medical technologists (men: 27, women: 72) who are not engaged in microscopic laboratory work. All were under 50 years old. We distributed questionnaires to them about health problems. Using a logistic regression model, we examined differences in physical complaints between cytotechnologists and medical technologists. We used multiple regression analysis for ocular fatigue 1 score related factor, ocular fatigue 2 score related factor, and fatigue score.
Result: Significant differences were seen in elbow pain, shoulder pain, myopia, difficulty in viewing objects at short distances, and the degree of dazzling with a cytotechnologist by a logistic regression model. Ocular pain, blepharospasm, dry eye, depression of accommodation reflex, arm pain, carpus pain, and back pain were associated with cytotechnologist works and by multiple regression analysis.
Conclusion: Health problems were occur typical of microscopic work, with declining ocular refractivity seemingly peculiar to cytotechnologists.View full abstractDownload PDF (833K) -
Ritsuko IMAI, Sonoko NATSUME, Rie OIKE, Mizuho TANAKA, Nobuko UJIHIRA, ...2006 Volume 45 Issue 6 Pages 318-322
Published: November 22, 2006
Released on J-STAGE: November 08, 2011
JOURNAL FREE ACCESSObjective: We studied the frequency with which (1) urothelial carcinomas were concomitant with flat lesions composed of grade 1 urothelial carcinoma cells (G1 flat lesions), (2) cells derived from G1 flat lesions were recognized in urinary cytological smears and their cytological features, and (3) histological features of G1 flat lesions reacting positively to Cytokeratin 20 (CK-20).
Study Design: We observed (1) histological preparations of 47 urothelial carcinomas of the urinary bladder, and (2) urinary cytological smears from voided urine in 18 cases of G1 flat lesions and CK-20 immunohistochemical stainning preparations of G1 flat lesions and urothelial carcinomas.
Results: G1 flat lesions were recognized in 57% of urothelial carcinomas. Cells from G1 flat lesions were small in nuclear size and few in number in urinary cytological smears and appeared in 61% of those from urothelial carcinomas with G1 flat lesions. Some 56% of G1 flat lesions reacted positive by to CK-20.
Conclusions: Cells derived from G1 flat lesions may appear in cytological smears even after main papillary tumors have been resected. G1 flat lesions are thought to correspond to urothelial dysplasia in the WHO classification of tumors of the urinary system.View full abstractDownload PDF (1951K) -
Mikiko ISHII, Kana MIYATA, Takashi KOJIMA, Tohru AKAMINE, Jun-ichi KAW ...2006 Volume 45 Issue 6 Pages 323-328
Published: November 22, 2006
Released on J-STAGE: November 08, 2011
JOURNAL FREE ACCESSBackgound: We report a very rare case of parathyroid carcinoma, cytologically compared to other neck tumors arising from the parathyroid and thyroid.
Case: A 49-year-old woman with an anterior neck tumor had, since 4 years earlie, undergone hemodialysis, with parathyroidectomy and autotransplantation of hyperplastic parathyroid tissue. Three years late, a 12×14×5cm recurrent tumor became palpable. A parathyroid tumor was suspected cytologically but we could not decide whether it was malignant or benign.
Needle aspiration cytology showed sheet-like cell clusters with minimal nuclear atypia, so it was difficult to definitively diagnose parathyroid carcinoma with the cytological study alone.
The histological diagnosis was parathyroid carcinoma arising from autotransplanted hyperplastic parathyroid tissue.
Comlusions: Despite the lack of cytological diagnosis of parathyroid diseases containing hyperplasia and neoplasia, we should suspect these if clinical and endocrinological findings are positive when screening specimens from the cervical region.View full abstractDownload PDF (3922K) -
Keiko YOSHIDA, Yoshimitsu MIYAHIRA, Muneo IWAI, Keiko MIYAMOTO, Mitsua ...2006 Volume 45 Issue 6 Pages 329-332
Published: November 22, 2006
Released on J-STAGE: November 08, 2011
JOURNAL FREE ACCESSBackground: Primary sphenoid sinus tumors (squamous cell carcinoma) are quite rare, with only 8 cases have been reported in the Japanese literature. We report imprint cytological findings of poorly differentiated sphenoid sinus squamous cell carcinoma involving the clivus.
Case: A 49-year-old man admitted for headache and visual disturbance was found in radiography to have a clivus tumor. Cytological analysis showed many mildly dyskaryotic squamous cells, but the majority of tumor cells were quite poorly differentiated and had a monotonous appearance, making definite classification difficult in routine Papanicolaou staining alone. Immunocytochemical analysis was quite useful for classifying this tumor.
Conclusions: Immunocytochemical analysis of poorly differentiated sphenoid sinus carcinoma has practical significance for definitive diagnosis and the appropriate choice of therapeutic methods.View full abstractDownload PDF (1765K) -
Joji SEKINE, Katsumi HIDESHIMA, Shuichi FUJITA2006 Volume 45 Issue 6 Pages 333-336
Published: November 22, 2006
Released on J-STAGE: November 08, 2011
JOURNAL FREE ACCESSBackground: We report a case of polymorphous low-grade adenocarcinoma (PLGA) of the palate showing features similar to adenoid cystic carcinoma (ACC) in smear cytology.
Case and Conclusion: Imprint specimens from the cut surface of biopsied tissue in a 78-year-old woman with a painless mass in the palate contained many neoplastic cells arranged in tight clusters, and mucous ball-like structures, pseudopapillary, tubular, and solid patterns were observed. Cells forming these clusters varied in size and had abundant eosinophilic, granular cytoplasm. Nuclei were round to oval and had a relatively smooth configuration. Although ACC was suspected cytologically, PLGA was confirmed by histopathological section. As opposed to imprint specimens obtained from resected tumors, no indian file arrays or concentric targetoids were detected in the imprint from the biopsied specimen, which thus led to diagnostic failure.View full abstractDownload PDF (2367K) -
Naoko NISHIYAMA, Kunihiro NISHI, Kenichi NISHIYAMA, Youichi HACHITANDA ...2006 Volume 45 Issue 6 Pages 337-340
Published: November 22, 2006
Released on J-STAGE: November 08, 2011
JOURNAL FREE ACCESSBackground: A patient of stage N gastric cancer in whom cytological examination of the operative washings revealed papillary clusters of tumor cells with many psammoma bodies is presented.
Case: A 59-year-old woman with stage IV gastric cancer underwent total gastrectomy. Presence of an ovarian tumor was suspected basedon findings on intraoperative cytology. One month after the initial operation, total hysterectomy and bilateral salpingo-oophorectomy were performed. Cytology of the intraoperative washings showed papillary clusters of tumor cells with minimal cellular atypia and numerous psam moma bodies, suggestive of serous papillary adenocarcinoma. Histologi cally, the resected ovaries showed the features of serous fibroadenoma with psammoma bodies. Psammoma bodies were also detected in the serosa of the sigmoid colon, pouch of Douglas, fallopian tubes and uter ine cervix.
Conclusion: In general, when clusters of epithelial cells are found on cytological examination of intraoperative washings, the cells must be sus bected as originating from metastatic lesions of other primary tumors. However, the possibility of the cells originating from benign ovarian tumors should also be borne in mind.View full abstractDownload PDF (3316K) -
Tsuyoshi NAKAMOTO, Tomomi MIZOKAMI, Akiko IKUTA, Junko SAITO, Hideharu ...2006 Volume 45 Issue 6 Pages 341-345
Published: November 22, 2006
Released on J-STAGE: November 08, 2011
JOURNAL FREE ACCESSBackground: We report a rare case of ovarian insular carcinoid with massive ascites.
Case: A 72-year-old woman reporting abdominal distension was diagnosed clinically with bilateral ovarian tumors with massive ascites based on USG and MRI. Tumor markers measured preoperatively were elevated, with CAl25 of 366.6U/ml, CA19-9 of 63.5 U/ml, SLX of 84 U/ml and CEA of 7.5 ng/ml. Laparotomy showed, a solid tumor originating from both ovaries with massive ascites, necessitating. Total abdominal hysterectomy, bilateral salpingo-oophorectomy, and omentectomy. Pathologically, the right ovarian tumor was mature cystic teratoma and the left insular carcinoid. Cytological specimens of ascites showed that tumor cells with light-green stained granular cytoplasm, oval to round nuclei, and coarse granular chromatin were arranged in clusters or rosette-like formations. Immunohistochemically, tumor cells were positive for Grimelius, chromogranin A, NSE, AE-1, Serotonin, CD56, and CEA, but were negative for Peptide YY. Cytologically, cells were positive for chromogranin A.
Conclusions: Typical cytological findings in ascites are, in addition to histological examination and immunohistochemistry, useful in diagnosing ovarian insular carcinoid.View full abstractDownload PDF (3148K) -
A case reportNoriko ABE, Syouichiro SANADA, Tomoko HARADA, Tatsunari SATAKE, Nobuo ...2006 Volume 45 Issue 6 Pages 346-347
Published: November 22, 2006
Released on J-STAGE: November 08, 2011
JOURNAL FREE ACCESSWe report cytological features in a case of ovarian transitional cell carcinoma. A 60-year-old woman seen for irregular genital bleeding was found in MRI to have a left ovarian tumor accompanying ascites. The uterus and bilateral ovaries were resected. Cytological examination of ascites showed many small round or oval cells with a relatively high N/C ratio and conspicuous irregular nuclei as clusters or single cells. The average nuclear size of 50 nuclei was 9μm on the long axis and 6.4μm on the short axis. Our case underlines the need to consider the possibility of ovarian transitional cell carcinoma when observing the cytological features described above in ascitic smears.View full abstractDownload PDF (981K)
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