The Journal of the Japanese Society of Clinical Cytology
Online ISSN : 1882-7233
Print ISSN : 0387-1193
ISSN-L : 0387-1193
Volume 46, Issue 5
Displaying 1-3 of 3 articles from this issue
Original Articles
  • Yutaka MORIMURA, Seiko CHIBA, Mariko ITO, Kazuhiro TAKAHASHI, Kaoru KA ...
    2007 Volume 46 Issue 5 Pages 251-255
    Published: September 22, 2007
    Released on J-STAGE: July 18, 2008
    JOURNAL FREE ACCESS
    Objective : We analyzed the results, frequency, and term of follow-up in patients with abnormal cytology found in mass screening for uterine cervical cancer.
    Study Design : From 1995 to 1999, 514407 participants underwent screening for uterine cervical cancer in Fukushima Prefecture. In 3821 patients with abnormal cytology, we compared positive predictive vales of over CIN3 between the first detailed examination and during follow-up. The frequency and term of follow-up in patients with the disappearance of abnormal cells were compared with those in patients with over CIN3.
    Results : In 3372 patients with class IIIa, 103 cases of over CIN3 were detected at initial examination, and 65 cases were detected during follow-up. The positive predictive value of 5.1% at overall examination was significantly higher than that of 3.1% at initial examination. In 271 patients with class IIIb, 79 cases of over CIN3 were detected at initial examination, and 28 cases were detected during follow-up. The positive predictive value of 39.9% at overall examination was significantly higher than that of 29.2% at initial examination.
    In patients with class IIIa and IIIb, 2388 (70.8%) and 74 (27.3%) patients had follow-up discontinued due to the disappearance of initial abnormal cells.
    Conclusion : Follow-up of patients with class IIIa and IIIb cytology may significantly increase the positive predictive values of over CIN3 than at first examination. Follow-up should thus be may repeat for as long as necessary in patients who had not been detected with over CIN3 in earlier examinations. More detailed cytological reports based on the Bethesda system may distinguish patients with mildly abnormal cytology not requiring follow-up from patients referred for colposcopy.
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  • Naruaki MATSUI, Kanako WAKUI, Hitoshi ITOH, Masanori YASUDA, Shinkichi ...
    2007 Volume 46 Issue 5 Pages 256-261
    Published: September 22, 2007
    Released on J-STAGE: July 18, 2008
    JOURNAL FREE ACCESS
    Background : We discuss the typical cytologic features of sclerosing hemangioma (SCH) of the lung and propose a cytological SCH subclassification.
    Study Design : A comparative analysis was conducted of 5 cases of SCH of the lung studied by curettage or imprint cytology and 10 cases of well differentiated adenocarcinoma of the lung.
    Results : The cytological subclassification of the SCHs was : type A, papillary clusters with hyalinized fibrous core ; type B, papillary clusters without hyalinized fibrous core ; type C, sheet-like clusters ; type D, overlapping cell clusters ; type E, scattered tumor cells.
    Conclusions : The arrangement of cell clusters and nuclear findings are important diagnostic features of SCH. In addition to the conventional features, the following features can be used to differentiate SCH from well differentiated adenocarcinoma : 1) multiplicity of tumor cells, 2) type A and D cell clusters, 3) hyalinized fibrous core, 4) nuclear and cytoplasmic findings.
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  • Ritsuko IMAI, Sonoko NATSUME, Rie OIKE, Mizuho TANAKA, Nobuko UJIHIRA, ...
    2007 Volume 46 Issue 5 Pages 262-265
    Published: September 22, 2007
    Released on J-STAGE: July 18, 2008
    JOURNAL FREE ACCESS
    Objective : We studied differences between filter and autosmear methods as related to the degree of fading of urine cytological preparations.
    Study Design : We used 10 Papanicolaou staining preparations, seven years after preparations were made and 62 five years after. Each of the 72 urinary specimens was divided in two, and one preparation was made using a filter and the other an autosmear. We observed the degree of fading of urothelial cells, classified into three, (-) : no fading, (+) : fading of cytoplasm, and mild fading of nucleus, and (2+) : fading both cytoplasm and nucleus.
    Results : No fading was observed in any preparations made by the filter method.
    Urothelial cells in preparations at five years after those made by autosmear (A) method showed (-) : 18/62 (29%), (+) : 29/62 (47%), (2+) : 15/62 (24%), and at seven years, (-) : 1/10 (10%), (+) : 5/10 (50%), (2+) : 4/10 (40%).
    Conclusions : Preparations made by the filter method showed no fading, presumably due to using a specific technique protecting preparations from exposure to sunlight. The filter method is thus useful for observing urine preparations made in the past.
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