Cytological examination of direct smear slides for body cavity fluid or fine-needle aspiration (FNA) specimens is often complicated by the presence of contaminated erythrocytes on the cells of interest. Acetic acid/ethanol fixing solution is applied to FNA cytodiagnosis and intraoperative rapid cytodiagnosis because it reduces background staining caused by red blood cells more than that of usual ethanol fixing. Evaluated the effects of the acetic/ethanol fixing solution on various blood-containing samples and confirmed the advantages of acetic acid/ethanol fixation over usual ethanol fixation.
We report a case of pancreatic acinar cell carcinoma. This rare tumor originating in pancreatic acinar cells often occurs at the pancreatic head. The cytology shows typical tubular and/or rosette-like patterns of cells with relatively monotonous oval nuclei resembling pancreatic acinar cells. It may be very difficult to diagnose precisely due to its rarity and to the existence of similar pancreas tumors. A precise diagnosis would be possible if specific tumor features and diagnostic points were better known.