Objective : We assessed the diagnostic accuracy and specimen adequacy of endoscopic retrograde cholangiopancreatography (ERCP) brush cytologies prepared with the BD SurePath
TM method.
Study Design : We examined 31 cases with ERCP brush cytology from April 2013 to December 2014. We cut the brush head, rinsed it out in a vial with the CytoRich Red
TM fixative and prepared a specimen with the BD SurePath
TM method. These cases were classified as negative, suspicious, positive, and unsatisfactory and compared with the histological diagnosis.
Result : Of the 31, 9 were negative, 8 suspicious, 14 positive and 0 unsatisfactory. Of the 14 positive, 7 were diagnosed as an adenocarcinoma from the histology. Cells in a defined 13-mm diameter area were distributed in thin layers. Air-drying artifacts and crush artifacts were removed from all specimens, and good preservation was ensured.
Conclusion : The BD SurePath
TM method enabled the preparation of good specimens in which many cells were collected and from which unsatisfactory factor could be removed, thereby enhancing the diagnostic accuracy of ERCP brush cytology.
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