Tophaceous pseudogout is a disease of calcium pyrophosphate dehydrate （CPPD） deposition of joints. We report an unusual case of calcium pyrophosphate dehydrate involving the temporomandibular joint （TMJ）. The patient was a 48-year-old male with the chief complaint of pain in the left TMJ. Biopsy was performed under general anesthesia, and a diagnosis of contradiction as tophaceous pseudogout was obtained. When diagnosing nodular masses with calcification around the temporomandibular joint, it may be necessary to consider this disease as one of differentiation.

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Methotrexate-associated lymphoproliferative disorder （MTX-LPD）, which may develop in the oral cavity, is known to be associated with the administration of methotrexate. We herein report a case of MTX-LPD that developed in the buccal mucosa. The patient was a 64-year-old woman who had undergone long-term methotrexate treatment for rheumatoid arthritis and who complained of ulcer formation in the bilateral buccal mucosa. The pathological diagnosis was diffuse large B-cell lymphoma with Epstein-Barr virus-positive cells. The lesions improved following the withdrawal of methotrexate. The development of MTX-LPD in the buccal mucosa is very rare.

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Plasmacytosis is a chronic inflammatory disease that occurs in a body opening, such as the oral cavity or vulva, and is accompanied by mucosal redness, erosion, and edematous changes. Histopathological examination has revealed epithelial thinning and plasma cells. Plasmacytosis is a relatively rare disease with infiltration. Herein, we report a case of open-cell plasmacytosis that was successfully treated with corticosteroids despite difficulties in diagnosis and treatment.

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