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5 巻, 3 号
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鉄剤投与と本貧血の予防について衣笠 恵士, 遠山 博, 中西 敬, 北村 正, 三輪 史朗, 大谷 五良1958 年 5 巻 3 号 p. 93-97
発行日: 1958年
公開日: 2010/03/12
ジャーナル フリー42 to 49 per cent of the habitual blood donors, giving 200 to 400cc of blood monthly, showed specific gravity of their blood below 1.052.
Daily peroral administration of 40mg of Fe gluconate for 6 months was able to reduce the rate of this anemia group down to 9.4 to 10.5%, although that was not sufficient to prevent completely the depletion of stored iron.
From the results above described, it is concluded that the daily peroral administration of Fe gluconate more than 40mg may prevent the development of anemia in habitual blood donors.抄録全体を表示PDF形式でダウンロード (594K) -
山田 雅人, 牧田 光雄, 篠田 謙次1958 年 5 巻 3 号 p. 98-102
発行日: 1958年
公開日: 2010/03/12
ジャーナル フリーSince the animal's blood type was studied by Dolter in 1925, many works have been done on it also in Japan and studies on the blood type of dog were reported by Iseki in 1940.
In our present experiment of the dog blood type the following four points were observed:
1) The sera type of dog could be divided into 4 groups, α′ (22%), β′ (18.4%), α′β′ (35.2%) and O′ type (22.4%).
2) Based upon the partial antigenicity, dog blood cell was found to react with human antisera; 1.51per cent with anti A, 11.49per cent with anti B, 63.22per cent with both anti A and B and 23.78per cent with none of these antisera.
3) The cross-matching test of dog blood did not develop any sufficient classification, but some natural antibodies were proved.
4) Analysed by the antigenicity of dog blood cell, 4 types were grouped: DI (3.67%), DII (25.69%), DI, DII (31.19%) and X type (39.45%).抄録全体を表示PDF形式でダウンロード (1911K) -
内藤 良一, 生垣 賢, 金丸 光男1958 年 5 巻 3 号 p. 103-117
発行日: 1958年
公開日: 2010/03/12
ジャーナル フリー1. Fresh human plasma causes hemolysis of rabbit red cells in vitro and febrile reaction accompanying hematuria when injected intravenously to rabbits. The febrile reaction usually reaches to its maximum at the end of 2 hours after the injection. The reaction and hemolytic. factor are remarkably weakened by heating plasma at 56°C. for 30 minutes.
2. The reaction is caused by hemolysin and thermo-labile complement-like substance in fresh normal human plasma.
3. This kind of febrile response may be differentiated from of the essential “Pyrogen” by the characteristic of the latter, being thermo-stable and causing the maximum temperature rise without hematuria at the end of 1st hour when injected to rabbits.
4. However, febrile response of human plasma mixed with a small dosis of typhoid-vaccine (representing pyrogen-substance) is also weakened by heating the mixture at 56°C. for 30 minutes. In such case both kinds of febrile response become difficult to differentiate.
5. The authors suggest to add the following explanation to the Minimum Requirements in order to avoid blaming pyrogen-fee plasma as “pyrogen-positive”.
“Certain blood products, notably normal human plasma. may contain a hemolytic factor for rabbit red cells. The characteristic reaction consists of a febrile response, usually occurring after the first hour and accompanied by hematuria. This type of thermal response is not considered to be caused by pyrogen and should not be interpreted as a positive response within the meaning of the test.”抄録全体を表示PDF形式でダウンロード (2082K) -
山田 雅人, 牧田 光雄, 篠田 謙次, 関根 活郎, 広木 文雄, 柳沢 昭吾, 黒河 輝久1958 年 5 巻 3 号 p. 118-124
発行日: 1958年
公開日: 2010/03/12
ジャーナル フリーThe irregular changes of MN agglutinin titer after blood transfusion was studied. Blood was obtained from the cubital vein of the lung tuberculosis patient who was transfused the blood over 2000ml.
1) The increase of M agglutinin titer at 5°C was observed in one of 30 cases tested, but this titer did not show any changes at 37°C.
2) One case showed increase of the cold agglutinin titer.
3) The increase of complete antibody titer resulted in 10 of 21 cases tested and decrease in only one case. The increase of anti-A agglutinin titer in O typed patient was observed.抄録全体を表示PDF形式でダウンロード (866K) -
椎名 千春1958 年 5 巻 3 号 p. 125-143
発行日: 1958年
公開日: 2010/03/12
ジャーナル フリーSeries of surveys of plasma hemoglobin concentration of stored blood, survival of erythrocytes after transfusion, concentration of hemoglobin and bilirubin in recipient's plasma and quantitative estimations of urobilinogen contents in urine and feces of the recipients, transfused with stored blood, lead to the following conclusion:
Hemolysis was more accelerated by the contact of blood with needles, filters, glass- and rubber tubes in the course of transfusion. The survival of erythrocytes of stored blood was shorter than of normal erythrocytes. Circulating chromoprotein amount in plasma of recipients was changed in parallel with its concentration. Plasma hemoglobin reached the highest value at 7th day and bilirubin was 9th day after transfusion. The shift of urobilinogen contents in urine and feces was related with plasma bilirubin content in recipients.
From the studies of chromoprotein metabolism it was concluded as follows:
As blood aged, the amount of hemoglobin and the number of erythrocytes in recipients coming from transfused blood were gradually increased.
Subsequently the transfusion of the shorter stored blood could produce the more similar therapeutic effects to the fresh blood.抄録全体を表示PDF形式でダウンロード (2653K)
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