Journal of the Japan Society of Blood Transfusion
Online ISSN : 1883-8383
Print ISSN : 0546-1448
ISSN-L : 0546-1448
Volume 50, Issue 6
Displaying 1-8 of 8 articles from this issue
  • Akimichi Ohsaka, Hitoshi Ohto, Atsushi Kikuta, Akira Ohara, Ichiro Tsu ...
    2004 Volume 50 Issue 6 Pages 739-745
    Published: December 20, 2004
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
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  • Toshiya Ohsawa, Yuka Nakajima, Yoshiaki Furuta, Kayoko Yanagidate, Kay ...
    2004 Volume 50 Issue 6 Pages 746-752
    Published: December 20, 2004
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
    To prevent incorrect blood transfusion attributable to misidentification of the patient or blood unit, we developed a novel computer-assisted blood transfusion management system which connects with the barcode patient-blood unit identification system. The system is composed of 1) a hand-held computer that reads the barcodes of the patient's wristband, the blood unit, the compatibility report form and the compatibility label attached to the blood pack, 2) a computer-assisted blood transfusion management system capable of receiving the patient's transfusion data from a bedside hand-held computer, and 3) an automated blood testing instrument (GelStation). This system permits a decrease in the number of manual procedures in multiple steps of the blood transfusion process and the monitoring of bedside verification procedures in real-time at the transfusion laboratory, together resulting in the minimization of human errors and the improvement of transfusion safety. Further evaluation is needed to establish whether this barcode patient-blood unit identification system may play a role in increasing transfusion safety.
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  • A COMPARISON OF AHG-LCT, LIFT, PIFT, MAGNETIC MPHA AND FlowPRA METHODS
    Satoshi Saito, Masao Ota, Yoshihiko Katsuyama, Hideki Makishima, Toyoh ...
    2004 Volume 50 Issue 6 Pages 753-760
    Published: December 20, 2004
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
    A total of 15 distinct human sera that did not exhibit reactivity against HPA antibodies but contained HLA-specific antibodies were used for sensitivity analysis of the AHG-LCT, LIFT, PIFT, M-MPHA and FlowPRA methods. The HLA antibody titer of each serum sample was defined as the highest dilution of serum that became positive to each method. 145 sera samples from patients receiving platelet transfusions were also screened to detect HLA antibodies by these methods. Results showed that FlowPRA was the most sensitive for identifying HLA antibodies. Although FCM is generally considered the most sensitive method, our analysis suggests that M-MPHA is as useful as FCM in both sensitivity and screening tests. PIFT sensitivity was slightly less than that of LIFT and M-MPHA. AHG-LCT sensitivity was significantly less than that of the other methods.
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  • Tomoko Takagi, Kazumasa Kajiro, Yurika Yazawa, Yuko Takada, Toshio Tak ...
    2004 Volume 50 Issue 6 Pages 761-767
    Published: December 20, 2004
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
    We evaluated the appropriateness of usage of fresh frozen plasma (FFP) and albumin for patients in internal medicine in seven general of Tokyo Metropolitan hospitals according to blood usage guidelines revised in 1999. We investigated patients with hepatoma or disseminated intravascular coagulation (DIC) in 1999, and all patients in internal medicine except for those undergoing plasma exchange in 2000.
    The total number of patients entered in the study for FFP and albumin was 279 and 250, respectively. FFP transfusion was judged appropriate when used in patients whose prothrombin time (PT) was 30% or less. Albumin administration was judged appropriate if used for patients with hypoalbuminemia below 3.0g/dL and with circulation failure, or in patients with hypoalbuminemia below 2.5g/dL without circulation failure. We judged the usage of FFP or albumin to be inappropriate if the PT value of patients for FFP or serum albumin value of patients for albumin was not measured before usage. Appropriate usage rate of FFP in patients with hepatoma or DIC was 16.2% in 1999 and 20.8% in 2000. In contrast, the appropriate usage rate of albumin from 1999 to 2000 was 65.2%.
    This study will help in assessing the degree of publicity received by the blood usage guidelines and the future direction of this publicity.
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  • Ken Ishimaru, Chika Tenman, Yoshikazu Fujiwara, Masashi Ohe, Toshiaki ...
    2004 Volume 50 Issue 6 Pages 768-773
    Published: December 20, 2004
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
    We report here a rare case of delayed hemolytic transfusion reaction (DHTR) probably caused by a primary immune response. The patient was a 32-year-old Japanese female who underwent surgery for ectopic pregnancy. For treatment of intraoperative hemorrhage shock, she received 5 units of RBCs (all positive for Jka, C and e antigen) that were crossmatch-compatible by indirect antiglobulin testing using polyethylene glycol (PEG-IAT). On day 22 after transfusion, she showed symptoms of hemoglobinuria, reticulocytosis, and elevated serum levels of LDH (1, 106IU/L) and total-bilirubin (5.6mg/dL). She did not receive further transfusion during this period. On irregular antibody screening of patient serum collected 24 days after transfusion, anti-Jka was detected by PEG-IAT. Her blood was typed as B, DccEE, Jk (a-b+). She then received 1 unit of RBCs (Jka-negative but C, e-positive). Her anemia improved after transfusion and no hemolytic transfusion reaction was observed. IgM type anti-C+e in the patient detected on day 24 after the first transfusion did not seem to be involved in the DHTR because transfusion of C+e+RBCs on the 24th day did not cause DHTR. Further, we demonstrated that the immunoglobulin (Ig) class of the anti-Jka switched from IgM to IgG during the clinical course. These results suggest that the DHTR was probably due to anti-Jka caused by a primary immune response.
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  • Kimiko Yurugi, Takeshi Yuasa, Hiroaki Tsuji, Norimi Niwa, Yoko Akai, R ...
    2004 Volume 50 Issue 6 Pages 774-779
    Published: December 20, 2004
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
    For centralized blood services, the establishment of intelligent systems to secure the quality of blood products is mandatory. One such responsibility is to control the temperature of blood products, because inappropriate storage conditions can ultimately pose a life-threatening risk to a patient. Although blood refrigerators have their own thermometer and record system, alarms are apt to be ignored and records are not well documented. In September 2002, we have established a centralized computer system to check the temperature of fifteen refrigerators at a blood service and two at a certain ward. Temperatures are remotely recorded, and when abnormalities occur, computer systems issue an alarm to staff at the blood service. In total, 107 records generated for one year were analyzed. One case involved the malfunction of the external cooling unit, while the remaining 106 with abnormally high temperature were caused by incomplete closure of refrigerator doors. When staff receive an alarm, they immediately check the records of the computer system, and then contact the ward or a 24-hour service company if needed. In conclusion, this computer system for temperature survey is useful in securing the quality of blood products and can save staff time by reducing troublesome tasks.
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  • 2004 Volume 50 Issue 6 Pages 805-806
    Published: December 20, 2004
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
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  • 2004 Volume 50 Issue 6 Pages 807-808
    Published: December 20, 2004
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
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