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Volume 8 (1961 - 1962･･･
- Issue 5-6 Pages 371-
- Issue 3-4 Pages 243-
- Issue 2 Pages 93-
- Issue 1 Pages 1-
Predecessor
Volume 8, Issue 5-6
Displaying 1-8 of 8 articles from this issue
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Goro UENO1962 Volume 8 Issue 5-6 Pages 371-375
Published: 1962
Released on J-STAGE: March 12, 2010
JOURNAL FREE ACCESSStudies on the heat-treated human plasma proteins made in U. S. A. (Plasmanate: 20 Lots) and Austria (PPF: 5 Lots), were performed with respects to pH, total protein content, hem content, sodium and potassium content, electrophoretic purity, heat stability by the turbidity of light-scattering method and precipition reaction in agar gel.
Both preparations are considered to be usefull and to cause no homologous serum hepatitis owing and no untoward reactions, although their safeness was not proved pharmacentically.View full abstractDownload PDF (614K) -
Keizo Yoshimura, Yoshitaka Furukawa, Akira Mizuno, Yuuji Kojo1962 Volume 8 Issue 5-6 Pages 376-382
Published: 1962
Released on J-STAGE: March 12, 2010
JOURNAL FREE ACCESSRecently, it has become possible to perform massive blood transfusions far above the normal human circulating volume with the advance of transfusions techniques.
We observed statistically 35 cases which required tranfusions over 10, 000ml during and within 24 hours after operation.
These patients (total 7243) were admitted and operated at 2nd Surgical Clinic of Tokyo University Hospital and The National Sanatorium of Kiyose Hospital during 5 years from 1956 to 1960.
The results are as follows:
1) The average rate of incidence of massive transfusion was 0.48%, but in the last 2 years it became to 1% and these cases tend to increase year by year.
2) The majority of these cases occured with pulmonary and vascular surgery.
3) Eighteen cases died during or soon after operation. The volume of transfusion and mortality were directly related in our cases, and no cases survived who were transfused over 16, 000c.c.
Shock from bloodlos and pulmonary edema were the chief causes of death.
4) The occurance of anemia and gamma-globulinemia about 1 month after transfusion was very remarkable. These findings reflect to changes of that of bone mallow and liver function.View full abstractDownload PDF (876K) -
Tetsuo Asanuma1962 Volume 8 Issue 5-6 Pages 383-394
Published: 1962
Released on J-STAGE: March 12, 2010
JOURNAL FREE ACCESSLactic acid dehydrogenase (LDH) activity in whole blood or serum has been proved by various investigators. Most of their methods for the estimation of LDH activity were electrophotometric determination of the reduction of diphosphopyridine nucleotide.
The author tried to estimate LDH activity with the use triphenyl tetrazolium chloride (TTC). The reduction of TTC was, however, not observed at all.
The blood constituents were added to the reaction mixture in phosphate buffer containing TTC lactate and lactic dehydrogenase obtained from guinea pig liver,
Results indicated that TTC reduction was inhibited by the addition of red blood cell. the nature of inhibition were summaried as follows.
1. The inhibitory action of red blood cell could tolerate against the temperature of 58°C and survive 65°C for 5 minutes.
2. When the red blood cell was treated with acetone, the inhibitor was not found in the solution, and precipitated completely.
3. The inhibtory action was found in the blood of rabbit, guinea pig, sheep and also of human beeing.
4. The mechanism of this action was supposed to the substance contained in red blood cell, which inhibited hydrogen transfer from lactic acid to TTC.View full abstractDownload PDF (1432K) -
Tetsuo ASANUMA, Yoshihiro Matsumura, Eiichi Tokunaga1962 Volume 8 Issue 5-6 Pages 395-398
Published: 1962
Released on J-STAGE: March 12, 2010
JOURNAL FREE ACCESSIt has been known that the viability of preserved erythrocytes derceases during storage in acid-citrate-dextrose at 4°-6°C, and this decrease is aseociated with a failure of cellular glycolytis.
Recently the isolation and analysis of human red cells glycolytic intermediates have been studied with the use of paper chromatography and ion exchange column chaomatography. Howevr the cause of the glycolytic failure has not been elucidated. This failure may be closely related the activities of the glycolytic enzymes of stored red cells.
In the present work the activity of aldolase in the stored red cell was studied with the use of Sibley's method.
Results indicated that aldolase activity of stored red cells remained constant during 40 days of storage at 4-6°C.
We conclude that the failure in glycolytic system is caused by inhibition due to the accumulation of metabolic products, and is not caused from the decrease of the activity of individual enzyme.View full abstractDownload PDF (497K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese]1962 Volume 8 Issue 5-6 Pages 399-401
Published: 1962
Released on J-STAGE: March 12, 2010
JOURNAL FREE ACCESSDownload PDF (340K) -
[in Japanese], [in Japanese], [in Japanese]1962 Volume 8 Issue 5-6 Pages 402-403
Published: 1962
Released on J-STAGE: March 12, 2010
JOURNAL FREE ACCESSDownload PDF (187K) -
Taro TSUCHIYA, Motozi KURATA, Mitsuo YOKOYAMA, Noboru SATOU1962 Volume 8 Issue 5-6 Pages 404-409
Published: 1962
Released on J-STAGE: March 12, 2010
JOURNAL FREE ACCESSThe Graydon (Gr) blood group was found in Australia in 1943 and was reported by Graydon in 1946. This blood group antigen was considered to be a “family” blood group at that time. In addition, another new blood group antigen, Verweyst (Vw) was described by van der Hart, Bosman and van Loghem in 1954.
The anti-Gr antibody was found in the normal human serum and anti-Vw antibody production was considered as results of pregnancy. The both anti-sera reacted better at lower temperature than at 37°C.
Recently, we found an atypical antibody in the serum of tuberculosis patient and the serum is contained anti-Lae antibody however, when the patients serum reacted with one of the Le (a-) donor's cells in saline, albumin and by indirect coombs tests but not by enzyme method.
This unknown antibody in the patient's serum which was conbined with anti-Lea antibody was confirmed as probably anti-Vw by Dr. J. A. Allen (Blood Grouping Laboratory of Boston).
Therfore, the donor' cell which was Le (a-) but reacted with this patient's serum probably possesed the Vw blood group antigen.View full abstractDownload PDF (733K) -
Koichi TOMITA, Masaru TASAKA1962 Volume 8 Issue 5-6 Pages 410-415
Published: 1962
Released on J-STAGE: March 12, 2010
JOURNAL FREE ACCESSThe authors observed a pronounced development of anti-Rh antibody. in the serum of a patient given a number of blood transfusions during two different surgical procedures, The operations were the removal of a Uterine Myoma in Aug. (1959) and total resection of the right lung in the next year.
When one of the authors made arrangement for the operation in June (1960), rather definite side reactions became evident with each blood transfusion.
The execution of the Total Resection was adjourned to Sept. (1960) so that a good deal of blood of d gaoup was prepared. The examination of the srrum of the patient showed the presence of complete anti-D agglutinin which was not present at the time of the first operation. The actual titre of the incomplete anti-D agglutinin with ficinized D cells was more than 1:1000 even in Aug. (1960). It was also observed that there was a small amount of anti-Lea agglutinin in the serum.
This case was found when Tasake (one of the autnors) was on duty at the Hiroshima Nationol Sanatorium.View full abstractDownload PDF (724K)
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