巻号一覧
8 巻, 5-6 号
選択された号の論文の8件中1～8を表示しています
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上野 五郎1962 年 8 巻 5-6 号 p. 371-375
発行日: 1962年
公開日: 2010/03/12
ジャーナル フリー米国製並びにオーストリー製加熱人血漿蛋白について, pH, 蛋白質量, ヘム含量, ナトリウム及びカリウム含量, 電気泳動法による純度, 光散乱法による混濁度からみた安定性, ゲル内沈降反応, などの生物化学的性状を検討した結果, 製剤としての改良の余地はあるが, 60℃, 10時間の加熱処理によつて血清肝炎の感染を防止しかつそれに伴う有害な作用を生じない人血漿蛋白液であると認められた.抄録全体を表示PDF形式でダウンロード (614K) -
吉村 敬三, 古川 俟隆, 水野 明, 古城 雄二1962 年 8 巻 5-6 号 p. 376-382
発行日: 1962年
公開日: 2010/03/12
ジャーナル フリーRecently, it has become possible to perform massive blood transfusions far above the normal human circulating volume with the advance of transfusions techniques.
We observed statistically 35 cases which required tranfusions over 10, 000ml during and within 24 hours after operation.
These patients (total 7243) were admitted and operated at 2nd Surgical Clinic of Tokyo University Hospital and The National Sanatorium of Kiyose Hospital during 5 years from 1956 to 1960.
The results are as follows:
1) The average rate of incidence of massive transfusion was 0.48%, but in the last 2 years it became to 1% and these cases tend to increase year by year.
2) The majority of these cases occured with pulmonary and vascular surgery.
3) Eighteen cases died during or soon after operation. The volume of transfusion and mortality were directly related in our cases, and no cases survived who were transfused over 16, 000c.c.
Shock from bloodlos and pulmonary edema were the chief causes of death.
4) The occurance of anemia and gamma-globulinemia about 1 month after transfusion was very remarkable. These findings reflect to changes of that of bone mallow and liver function.抄録全体を表示PDF形式でダウンロード (876K) -
浅沼 哲雄1962 年 8 巻 5-6 号 p. 383-394
発行日: 1962年
公開日: 2010/03/12
ジャーナル フリーLactic acid dehydrogenase (LDH) activity in whole blood or serum has been proved by various investigators. Most of their methods for the estimation of LDH activity were electrophotometric determination of the reduction of diphosphopyridine nucleotide.
The author tried to estimate LDH activity with the use triphenyl tetrazolium chloride (TTC). The reduction of TTC was, however, not observed at all.
The blood constituents were added to the reaction mixture in phosphate buffer containing TTC lactate and lactic dehydrogenase obtained from guinea pig liver,
Results indicated that TTC reduction was inhibited by the addition of red blood cell. the nature of inhibition were summaried as follows.
1. The inhibitory action of red blood cell could tolerate against the temperature of 58°C and survive 65°C for 5 minutes.
2. When the red blood cell was treated with acetone, the inhibitor was not found in the solution, and precipitated completely.
3. The inhibtory action was found in the blood of rabbit, guinea pig, sheep and also of human beeing.
4. The mechanism of this action was supposed to the substance contained in red blood cell, which inhibited hydrogen transfer from lactic acid to TTC.抄録全体を表示PDF形式でダウンロード (1432K) -
浅沼 哲雄, 松村 義寛, 徳永 栄一1962 年 8 巻 5-6 号 p. 395-398
発行日: 1962年
公開日: 2010/03/12
ジャーナル フリーIt has been known that the viability of preserved erythrocytes derceases during storage in acid-citrate-dextrose at 4°-6°C, and this decrease is aseociated with a failure of cellular glycolytis.
Recently the isolation and analysis of human red cells glycolytic intermediates have been studied with the use of paper chromatography and ion exchange column chaomatography. Howevr the cause of the glycolytic failure has not been elucidated. This failure may be closely related the activities of the glycolytic enzymes of stored red cells.
In the present work the activity of aldolase in the stored red cell was studied with the use of Sibley's method.
Results indicated that aldolase activity of stored red cells remained constant during 40 days of storage at 4-6°C.
We conclude that the failure in glycolytic system is caused by inhibition due to the accumulation of metabolic products, and is not caused from the decrease of the activity of individual enzyme.抄録全体を表示PDF形式でダウンロード (497K) -
大村 泰男, 小沢 啓邦, 深沢 義明, 長崎 真一1962 年 8 巻 5-6 号 p. 399-401
発行日: 1962年
公開日: 2010/03/12
ジャーナル フリーPDF形式でダウンロード (340K) -
鳥居 有人, 川井 三郎, 千島 雅太郎1962 年 8 巻 5-6 号 p. 402-403
発行日: 1962年
公開日: 2010/03/12
ジャーナル フリーPDF形式でダウンロード (187K) -
土谷 太郎, 蔵田 元二, 横山 三男, 佐藤 登1962 年 8 巻 5-6 号 p. 404-409
発行日: 1962年
公開日: 2010/03/12
ジャーナル フリーThe Graydon (Gr) blood group was found in Australia in 1943 and was reported by Graydon in 1946. This blood group antigen was considered to be a “family” blood group at that time. In addition, another new blood group antigen, Verweyst (Vw) was described by van der Hart, Bosman and van Loghem in 1954.
The anti-Gr antibody was found in the normal human serum and anti-Vw antibody production was considered as results of pregnancy. The both anti-sera reacted better at lower temperature than at 37°C.
Recently, we found an atypical antibody in the serum of tuberculosis patient and the serum is contained anti-Lae antibody however, when the patients serum reacted with one of the Le (a-) donor's cells in saline, albumin and by indirect coombs tests but not by enzyme method.
This unknown antibody in the patient's serum which was conbined with anti-Lea antibody was confirmed as probably anti-Vw by Dr. J. A. Allen (Blood Grouping Laboratory of Boston).
Therfore, the donor' cell which was Le (a-) but reacted with this patient's serum probably possesed the Vw blood group antigen.抄録全体を表示PDF形式でダウンロード (733K) -
富田 功一, 田坂 勝1962 年 8 巻 5-6 号 p. 410-415
発行日: 1962年
公開日: 2010/03/12
ジャーナル フリー著者等は輸血副作用から偶然見出された高力価の不完全抗D凝集素産生例について報告した. すなわち患者は昭和34年8月と35年6月の2度に亘り何回かのRh式血液型不適合輸血を受けたために, かゝいる完全及び不完全抗D凝集素を産生したものと思われる. 特に不完全凝集素はフイチン処理血球に対し最盛期には1000倍稀釈以上でも凝集反応を示すほど高力価のものであつた. またこの抗D抗体の産生とともに不完全抗Lae凝集素も弱いながら若干産生されたのではないかと推測されるが, この方は確認困難であつた.抄録全体を表示PDF形式でダウンロード (724K)
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