鼻腔内疾患が疑われた犬20症例に対して後鼻腔内視鏡生検を行ったところ、内視鏡所見と病理組織診断・細胞診所見の一致率は85%であり、後鼻腔内視鏡生検サンプルの最終的な診断率は95%であった。後鼻腔内視鏡生検で高い診断率を得るためには、内視鏡下でBoring biopsyを実施する事と治療に反応が悪い場合や画像診断所見と生検結果が明らかに異なった場合には再検査を実施することが重要であると考えられた。

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11歳齢、去勢雄のシーズーが急速に増大した下顎腫瘤を主訴に来院した。犬歯から下顎先端にかけて2.7×1.5 cm大の歯肉腫瘤がみられ、X線検査では著明な骨吸収像が認められた。初診時に行った生検でアミロイド産生性歯原生腫瘍（APOT）と診断された。初診から14日後には病巣はさらに増大しており（3.3×3.0 cm）、第2～3前臼歯を切断線とする両側吻側下顎骨切除術を実施した。切除組織には歯原性上皮細胞の増殖とともに、コンゴレッド染色で陽性を示すアミロイドの豊富な沈着が認められ、肉眼病巣の急速な拡大は腫瘍増殖のみでなく旺盛なアミロイド産生によるものと考えられた。組織学的に腫瘍は完全切除されており、術後46ヶ月間再発・転移は認められなかった。局所浸潤をともなって急速に増大するAPOTにおいては、下顎骨切除のような早期の拡大手術が有効な治療になると思われた。

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An 8-month-old female cat presented with a 1-month history of open-mouth breathing and intermittent regurgitation. Contrast radiography revealed megaesophagus (ME) with a large pharyngeal mass. The mass was removed by gentle traction under general anesthesia, after which the ME resolved within 9 days. The mass was diagnosed as a nasopharyngeal polyp based on clinical and histopathological findings. A similar polyp recurred 50 days postoperatively, and was also removed by traction followed by four treatments with methylprednisolone acetate. The cat remained asymptomatic for 9 months after the second surgery. This report demonstrates that ME resulting from a nasopharyngeal polyp may resolve spontaneously after polyp removal, but post-surgical glucocorticoid therapy may also be needed to decrease the chance of recurrence.

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A 13-year-old spayed female cat presented for chronic vomiting and weight loss. Ultrasonic examination identified an abdominal mass likely originating from thickened small intestine. Laparotomy revealed a mass involving ileum, cecum, and ascending colon. Affected tissues were resected, followed by end-to-end ileocolic anastomosis. Grossly, an abscess that did not continue to the intestinal lumen was present in the central area of the resected mass, from which Clostridium perfringens was isolated. Histopathologically, the area surrounding the abscess contained dense collagen trabeculae with marked eosinophilic infiltration, enabling diagnosis of feline gastrointestinal eosinophilic sclerosing fibroplasia (FGESF). Chronic vomiting almost resolved after surgery and body weight gradually increased. Administration of predonisolone was continued for 26 months to control mild enteritis. FGESF should be considered as a differential diagnosis for cats with abdominal mass, and treatment by surgical resection should be considered because of the possibility of intralesional bacterial infection.

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