An 11-month-old spayed Kinkalow cat (crossbreed of an American curl and a Munchkin) presented with acute vomiting and anorexia. Radiographic and ultrasound examinations revealed two mass lesions: one in the abdominal cavity and one originating from the thoracic wall. Histopathological examination of the mass revealed a malignant peripheral nerve sheath tumor characterized by highly dysplastic and pleomorphic mesenchymal cells that were positive for anti-S100 antibody. The patient underwent surgery, and two tumor lesions were completely resected. However, on day 490, thoracic radiography revealed signs of lung metastasis, and the patient died of presumptive lung metastasis 520 days after the initial evaluation. We found no published clinical reports on malignant peripheral schwannoma in the abdominal cavities of cats at an early age; thus, the case seemed rare. Additionally, only two cases of metastasis of this tumor type have been reported to date. In these reports, tumor cell pleomorphism and multiple mass formations were considered possible causes of the metastasis.
A 14-year-old spayed long-haired mixed breed cat underwent forelimb amputation to treat a synovial sarcoma of the right forelimb. The cat was in good condition for 2 days postsurgery but suddenly became anorexic, and her general condition deteriorated. Blood tests showed leukopenia (1,790/μl) with neutrophil depletion (1,110/μl). Subsequently, the cat showed mild azotemia, an elevated serum total bilirubin concentration and jaundice. Abdominal ultrasonography revealed pancreatic swelling, and qualitative testing for feline pancreatic-specific lipase yielded a strongly positive result. The cat was diagnosed with postoperative acute pancreatitis of unknown causes and underwent medical treatment for pancreatitis. The treatment resulted in improved blood test results and an improved general condition. Eight months after the first visit, the cat remains in good general condition. This case revealed that acute pancreatitis can occur after surgery without intraperitoneal manipulation in cats. Veterinarians should recognize that feline leukopenia is one early clinical symptom of acute pancreatitis in cats.