A study is made of 294 fatal tuberculous cases in Osaka for 1954 and 1955 in reference to their respective families, centering around their morbid course and living conditions. It is attempted to find out if any changes have been introduced to clinical and living conditions of the tuberculous. The results obtained are as follows: The survival period after onset is 3 years and 4 months on an average. About 50 per cent are fatal within 2 years after onset. About 80 per cent have neither remission nor relapse,30 per cent are treated with no or less than 35 g. of streptomycin,60 per cent are nonhospitalized, the hospitalization period is one year on an average. The survival period after onset is shorter for non-insurance patients than that for social insurance patients.
For a tuberculosis control, an attempt is made to study the special features of tuberculosis prevalence in a certain district in reference to the social factors and living conditions of its residents. For that purpose it seems necessary to obtain practional data on a locality basis. The data include the average survival period and the survival rate after onset of fatal tuberculous cases(cumulative mortality curve)and Δindex(total fatal cases/fatal cases within one year after onset), which are obtained from the death toll reported to a health center in charge.
A study has been made how the movement of the tissue fluids is influenced by the dye powder method. The results obtained are as follows: A. Adrenalectomized mice 1. Following adrenalectomy the tissue fluids is lost. The humidity of the tissues decreased greatly. Therefore there appear a decreased movement of the tissue fluids, i. e., a narrow halo forming surrounding dye masses, a markedly decreased infiltration of the dye into blood capillaries, a markedly decreased dye movement along venuleous walls and a markedly decreased absorption of the dye into the lymphatic vessels. 2. After injection of cortisone, the tissue fluids of adrenalectomized animals considerably increase. Therefore a decreased movement of the tissue fluids of adrenalectomized mice considerably restores, i. e., there appear a halo resembling a normal halo surrounding the dye masses and considerably vigorous dye movement along venuleous walls. However, there is still observed a decrease in infiltration of the dye into blood capillaries and in absorption into lymphatic vessels. 3. After injection of DOCA the amount of the tissue fluids of adrenalectomized animals increases to a small degree. Therefore the movement of the tissue fluids is not significantly restored. B. Sham operated mice 1. After injection of cortisone the amount of the tissue fluids of sham operated mice considerably decreases. Therefore the movement of the tissue fluids considerably decreases, i. e., suppression of a halo forming surrounding dye masses of a dye movement along venuleous walls, infiltration of the dye into blood capillaries, and absorption of the dye into lymphatic vessels are observed. 2. After injection of DOCA the amount of the tissue fluids considerably increases. Therefore the movement of the tissue fluids is considerably promoted. However, the absorption into lymphatic vessels is not so much promoted.
The influence of DOCA upon Arthus' phenomenon of sham operated rabbits and adrenalectomized rabbits were studied. The results were as follows: 1) The macroscopic findings of Arthus' phenomenon of the adrenalectomized animals injected with DOCA are markedly greater compared with those of non-operated animals. 2) The microscopic findings of Arthus' phenomenon of adrenalectomized rabbits injected with DOCA were as follows: edema was marked, hyperplasia of arteriols, vaquolar degeneration of endothels, thrombi-formation at the acute stage and plasma cell reactions at reconvalescent stage were considerably marked compared with those of the non-injected adrenalectomized animals. 3) Macroscopic findings of Arthus' phenomenon of sham operated rabbits injected with DOCA were similar to those of the control animals. Only the extent of edema was very wide. 4) Microscopic findings of Arthus' phenomenon of sham operated animals injected with DOCA were as follows: edema was marked; leucocytic reaction was considerably marked, however, it did not form an abscess, and degeneration of collagenous fibers and reactions of blood vessels were not significantly marked. 5) The inflammatory reactions of adrenalectomized animals were markedly suppressed, whereas the reaction became marked after the injection with DOCA, although the degree of reactions was considerably low compared with those of the animal injected with cortisone. 6) If DOCA is used in order to maintain the life of the adrenalectomized animals, the inflammatory reactions of adrenalectomized animals became marked compared with those of non-operated animals. Therefore in an attempt to study the inflammatory reactions of adrenalectomized animals, the method without DOCA is more usful than with DOCA. It was confirmed again that the inflammatory cell reactions of adrenalectomized animals were suppressed.
Anatomisches Institut der Kansai Medizinischen Hochschule Wir Verfasser haben experimentell die Regenerationsvorgange der Linse bei den Anurenlarve überblickt. 1. Die obere Iris ist immer das Reaktionsmaterial fur die Linsenregeneration. 2. Wir vermuten, daB der das Reaktionsmaterial aktivierende Faktor durch den Glaskorper von der Netzhaut gegeben wird. 3. Ausserdem konnen wir vermuten, daB der aktivierende Faktor auch durch die GefaBe vom Chorioidea gegeben wird. 4. Es wird auch vermutet, daB der aktivierende Faktor wie den induzierende die chemische Substanz ist. 5. Und noch konnen wir vermuten, daB der Regenerator (Retina und Chorioidea) regionell einen Teilfaktor von den allgemeinen Faktoren wahlt und wie der Induktor ihn dem Reaktionsmaterial gibt, oder der Regenerator ihnen das spezifische Element nachtraglich hinzusetzt.
ch implantierte homooplastisch das gesamte Gewebe von dem Gebiete des Mittel, Hinterhirns und der zweiten Myotome der einen Tieren in den Bauch der anderen bei vier Tierarten von den japanischen Anurenamphibienlarven, und befand, dass die Seitenorgane durch das Nervensystem induziert werden, also ich lehne die Harrison'sche Ansicht (1904)hartnackig ab, welch die Organe an der Anlage der Seitenlinie oder -organe durch ihre Energie selbstdifferenziert. 1. Die “Seitenlinieanlage”, welche Harrison beschrieb, ist ganz sicher ein verdickender Teil der Sinnesschichte der Epidermis. Demnach kann ich seine Ansicht nicht bestatigen, in der er betont, dass dieser Verdickungsteil bei Versuchtieren weithin sich erstreckt, dagegen die Epidermis wenig caudal von Myotomgrenze erwachst. Wenn die “Seitenlinienanlage” einer Komponente durch die Sinnesschicht der anderen Komponente sich erstrecken konnte, so musste dies auf den starksten Widerstand treffen. Diese Annahme steht im Gegensatz zu Harrisonischer Behauptung, dass die Wachstumsbahn von der Anlage der Weg vom geringsten Widerstand sei. 2. Harrison betont, dass die Seitenlinieanlage experimentell selbstdifferenziert, und ganz vom Nervensystem entwicklungsweise nicht abhangig ist. Aber ich sollte an das Vorhandensein von Entwicklungs-Wechselbeziehungen der beiden folgendermassen glauben.
Studies were carried out by means of the Kuhne's M. gracilis method every day from Oct.1950 to Sep.1951. There were four fundamental conduction systems of excitation upon the neuro-muscular junction of frog, e. g. typical isodromical system (reciprocal conduction), atypical isodromical system, heterodromical system (irreciprocal conduction) and apparently non-conducting system. However, there was seasonal variation in conduction system. During a certain period from July to February, isodromical conduction system was the most dominant. On the other hand, during another period from March to June apparently non-conductig system andheterodromical systems were dominant. Anyhow, these four fundamental systems conduction were reversible under certain condition e. g. administration of adrenaline.
Adrenal glands of frog were extirpated bilaterally following the Kotsuka's operation. The conduction systems of excitation upon the neuro-muscular junction of adrenalectomised frog were examined with the same method as described previously. Results obtained were as follows: 1) The conduction system were heterodromic or apparently non-conductive. From June to December, heterodromic system was dominant. On the other hand, from January to May apparently non-conducting system was relatively dominant. 2) After a certain period following the adrenalectomy the isodromical conduction system could not be found. 3) The conduction systems of adrenalectomised frog could be turned into the isodromical conduction system under certain condition e. g. administration of adrenaline.
1. It is demonstrated whith a new “glycerine spot method” (1952, Kotsuka) and a mechanical stimulation method that efferent glossopharyngeal vasodilator nerves exist in a frog's tongue. 2. Atropinized blood vessels in a frog's tongue are constricted when the cut peripheral end of glossopharyngeal nerves is stimulated with “glycerine spot method” and mechanical stimulation method. It is evidenced that there exist efferent glossopharyngeal vasoconstricting nerves in a frog's tongue. 3. The above findings demonstrate that blood vessels of frog's tongue are subject to a vasodilatation and vasoconstriction action of glossopharyngeal nerves i. e., glossopharyngeal double innervation action.
1. Blood vessels in a bull-frog's tongue are constricted when the cut peripheral end of hypoglossal nerves is stimulated with a new “glycerine spot method” and mechanical stimulation method. It is evidenced that there exist the efferent hypoglossal vasoconstricting nerves in a bull-frog's tongue. Hypoglossal nerves have been classically believed to be pure somatomotor nerves in the cerebral nerves. But it is demonstrated in the present experiment that vasoconstricting nerves which are visceromotoric exist in the hypoglossal nerves in a bull-frog. 2. Pertaining to a bull-frog, hypoglossal nerves are equivalent in terms of vasomotoric function to the anterior root of spinal nerves.
Décrite d'abord par HOFF et POETZL, l'agnosie des physionomies est comprise dans le cadre de la clinique neuropsychiatrique comme une forme particulière de la cécité psychique. Il s'agit d'une non-reconnaissance des physionomies humaines: le malade ne peut plus identifier des individus connus de lui, ni comprendre des expressions mimiques, seulement par le regard. En 1947, BODAMER rapporta sur trois cas personnels de ce syndrome curieux sous le nom de “prosopagnosie”. Dès lors apparaient de plusieurs travaux, que nous avons à passer en revue au cours de notre étude, par les auteurs tels qu'il suit; FAUST, PALLIS, HECAEN et DE AJURIAGUERRA, etc. Les deux observations nouvelles que nous avons recueillie jusqu'à maintenant, nous incitent a discuter ce syndrome pour le faire mieux comprendre.