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Volume 21 (1969)
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Volume 21, Issue 2
Displaying 1-11 of 11 articles from this issue
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(1) Influence of Radiation on the contents of Potassium and Sodium in Erythrocytes of RabbitMatsuko Sasa1969 Volume 21 Issue 2 Pages 1-9
Published: June 20, 1969
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSErythrocytes of rabbits were treated by Roentgen radiation in doses of from 100R to 5,000R and the following results were obtained.
1. The content of potassium in e rythrocytes irradiated in a dose of 2,000R was decreased at the temperature of 37°C. This result was assumed that the reduction of potassium content was caused by the disturbance of erythrocytes membrane irradiated.
2. If the erythrocytes were kept in cold room (4°C) immediately after the radiation even in a dose of 2,000R was done, the influence of radiation on erythrocytes was reduced.View full abstractDownload PDF (1559K) -
(I). On Glycolysis and Inosine FormationTomiyosi Ito1969 Volume 21 Issue 2 Pages 10-16
Published: June 20, 1969
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSThe antibody promoting factor, inosine, in a great amount of quantity has been shown to appear in the circulating blood in the early stage which is called the negative phase after an antigen invasion by our laboratory's reports. Thus the author set out to examine the interrelations between inosine formation and glycolysis in the negative phase. The results obtained were as follows:
1) Inosine formation varied i n contrast to the behaviors of ATP in mouse liver after the typhoid-paratyphoid vaccine (TPV) invasion. The variation was especially remarkable 60 minutes later.
2) Inosine which increased in the spleen was formed mainly in the liver and carried in it, through the circulation. When an adequate glucose was added in a liver homogenate enucleated and made 60 minutes after the TPV invasion and the incubation was continued in vitro for 1 hour, inosine formation was accelerated still more, and pH of the medium gradually turned acidic and fell to pH 6.4-6.5 in the end. NADH decreased slightly and SDH could hardly be discovered in the activity. When the homogenate of mice livers enucleated and made 1 hour after the first TPV invasion was incubated for 30 minutes, the amount of pyruvate in it was shown to increase slightly, also, uric acid increased with the addition of AICA in it. On the contrary, lactate and uric acid in the homogenate of the liver enucleated 1 hour after the second TPV invasion increased remarkably in comparison to the first and the quantity of pyruvate did not increase.View full abstractDownload PDF (1327K) -
(2). On the Mutual Relation between the Formation of Hemolysin Plaque Forming Cells and Some Interm ediates in Glycolysis.Tomiyosi Ito1969 Volume 21 Issue 2 Pages 17-24
Published: June 20, 1969
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSIn the present paper, the migrations of hemolysin plaque forming cells (HPFC) contained in the spleen were made 24 hours apart during ten days according to Jerne's method after the primary sensitization of sheep erythrocyte antigen (SEA), and in that corse, especially, the mutual relation in quantity-- on the one hand between formation of HPFC and of pyruvate, lactate, acetaldehyde, inosine (antibody promoting factor), uric acid, and on the other hand. -- NADH activity contained in the mouse spleen was examined, and the results obtained were as follows:
The formation of HPFC increased in quantity about 2 times 24 hours later and arrived to a maximal value 4-5 days later after the SEA invasion, i. e. it corresponded to about 240 times of non-treated control group in quantity and after that, it decreased abruptly to normal range in quantity in the mouse spleen. Both lactate and uric acid increased similarly and arrived to a maximal value 1-2 days before HPFC and on the contrary, inosine increased parallel to the behavior of HPFC daily, and pyruvate and acetaldehyde had almost no behaviour. The simple or combined pre-treatments of inosine and pyruvate into the peritoneal cavity for 7 days prior to the sensitization of SEA remarkably accelerated to about 2-3 times the HPFC formation as compared with non-pretreated control group, respectively.View full abstractDownload PDF (2486K) -
Kyoko Hata1969 Volume 21 Issue 2 Pages 25-48
Published: June 20, 1969
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSGrowth and proliferation during embryonic stage of the posterior silk gland of silkworm, Bombyx mori., have been studied electron microscopically. Growth of the gland could be described subdividing into the following three phases.
(1) The first phase (blastokinesis 24 hours).
This is the latent phase during which the growth in the next proliferation phase is to be prepared. Electron microscopical observations on the posterior silk gland cells have shown that, in this stage, there exist a number of free ribosomes in the cytoplasm. On the contrary, only a small number of endoplasmic reticulum are observable in this phase.
Golgi apparatus is very poorly developed and no Golgi vacuole is found.
(2) The second or proliferations phase (flastokinesis 48-96 hours)
The most striking change is observed in the rough endo plasmic reticulum: The rough endoplasmic reticulum starts to proliferate rapidly. The Golgi vacuoles are still few in number.
(3) The third phase or the stage of fibroin biosynthesis (blastokinesis 120 hours-just before hatchiability). The cytoplasm is mostly filled with tubular or vesicular endoplasmic reticulum, and the intracisternal spaces are now markedly distended. Golgi vacuoles, golgi vesicles, and free vacuoles (fibroin globules) are also quite numerous.
It is concluded that, in the early stage after the blastokinesis, the cellu lar structures necessary for the biosynthesis of fibroin are rapidly formed, while in the later stage the biosynthesis of fibroin proceeds at a maximum rate. These observations suggest that the synthesis and secretion of fibroin in the embryonal posterior silk gland are very similar to those in the fifth larval instar.View full abstractDownload PDF (22381K) -
Kyõko Ichiki1969 Volume 21 Issue 2 Pages 49-75
Published: June 20, 1969
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSA study was undertaken concerning the relationship between the electrical phenomenon of the central nervous system caused by stimulating rabbit's brain stem reticular formation and thalamus and the intestinal movement.
Simultaneously with the appeara nce of the spike and wave in the electroencephalograms by a 3 c/s electric stimulation of nucl. ventralis anterior (VA), nucl. centrum medianum (CM), the intestinal movement was observed to be accelerated. With the 8 c/s stimulation of VA, the intestinal movement was accelerated with consequence upon the onset of a recruiting response, but, in the case of 8 c/s stimulation of CM, the intestinal movement was seen to be either accelerated or inhibited. In the case of 100c/s stimulation of VA and CM, the intestinal movement indicated an inhibitory effect as the reselt of an arousal reaction.
By the 100c/s stimulation of the brain stem reticular formation, an arousal reaction was brought about, and consequntly, the intestinal movement was seen to be inhibited; when this inhibitory effect on the intestinal movement was relatively weak, much of the tonic type muscular discharge was seen in the fore and hind limbs, and on the other hand, when the inhibitory effect was strong, much of the tonic phasic type muscular discharge tended to, appear. T he inhibition of the intestinal movement by the stimulation of the brain stem reticular formation was not influenced at all by adrenalectomy and vagotomy, but it was observed to disappear by splanchnicectomy.
This inhibitory effect on the intestinal movement is assumed to be brought about via the splanchnic nerve.
The effects of cardiazol, strychnine, barbiturate, chlorpromazine, morphine, adrenaline, acetylcholine and atropine on arousal reaction and intestinal movement and the inhibitory effect of arousal reaction on intestnal movement were examined. As a result, it was assumed that the inhibitory effect of arousal reaction exerted on the intestinal movement emerges via a lower inhibitory center.View full abstractDownload PDF (5209K) -
Kokichi Kanazawa, Tadashi Kondo, Tatusji Hagihara1969 Volume 21 Issue 2 Pages 76-82
Published: June 20, 1969
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSThis patient died from gastric cancer.
However, in addition to gastri c cancer, our autopsy revealed a combined deposit of ceroid pigment and melanosis pigment, and fat necrosis of the pancreas. It is an infrequent disorder that a deposit of ceroid pigment occurs in the smooth muscle of the small intestine and a deposit of melanosis pigment in the mucosa of the large intestine. According to Braunstein, a ceroid pigment deposition was observed in the smooth muscle of the small intestine in 22 out of the 36 adult cases with chronic pancreatits which caused a tocopherol deficiency. On the other hand, ceroid pigment in the smooth muscle of the small intestine was observed by Blanc et. al. in autopsy cases of children with cystic fibrosis of the pancreas and congenital biliary atresia, and a similar case was reported by Kerner and Goldbloom.
The most important factor of a ceroid pigment deposition in the smooth muscle of the small intestine seems to be a deficiency of tocophrol caused by malabsorption of fats.View full abstractDownload PDF (2905K) -
Tadahisa Kurimoto, Satoru Kubota, Naoki Kageyama, Masao Wakeno, Sigeka ...1969 Volume 21 Issue 2 Pages 83-86
Published: June 20, 1969
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSA case reported in this paper showed peculiar seizures induced by sudden voluntary movements of the leg. The seizures were tonic or torsionlike spasms which was initiated in the unilateral lower extremity, preceded by abnormal sensation in the sole of the foot, and then followed by tonic seizures of the upper extremity on the same side. His consciousness was clear throughout the attack, the duration of which was about thirty to sixty seconds. The general physical examination and neurological examination revealed no abnormality and the laboratory examination was normal.
E. E. G. and pneumoencephalogram showed no thing abnormal. Diphenylhydantoin and phenobarbital was given to the patient, which was followed by complete disappearance of seizures. Several cases which seemed to be identical to the above patient have been reported in the literature. There are various different opinions on the pathogenesis and the name of the diseases, but a dysfunction of the basal ganglia is considered the most probable factor because of the characteristic features of the seizure and of the intact consciousness.View full abstractDownload PDF (1101K) -
Yoshiko Sameshima, Mineko Sasakawa, Takako Mizuno, Minoru Kamata, Shin ...1969 Volume 21 Issue 2 Pages 87-100
Published: June 20, 1969
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSEffects of urogastrone on gastric and duodenal ulcers were studied with a double blind method.
Urogastrone was given to 16 cases and lactose as placebo to 11 cases, each 4 capsules a day, for 42-56 days.
Clinical effects were evaluated on the basis of pre and post administration subjective symptoms, gastrocamera findings and G. I. X-ray data.
Fourteen cases (87.5%) out of 16 cases subjec t ed to urogastrone showed improvement of ulcer. Eight cases (72.0%) of 11 cases subjected to placebo were improved. It was found that urogastrone were effective, without adverse effects.View full abstractDownload PDF (6264K) -
[in Japanese]1969 Volume 21 Issue 2 Pages 101-108
Published: June 20, 1969
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSDownload PDF (3464K) -
[in Japanese]1969 Volume 21 Issue 2 Pages 109-114
Published: June 20, 1969
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSDownload PDF (1468K) -
[in Japanese]1969 Volume 21 Issue 2 Pages 115-119
Published: June 20, 1969
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSDownload PDF (2807K)
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