Electrophysiological studies were made on blinking in unanesthetized rabbits as to its development mechanism.
1. "Blink r eflex" was observed to developed unilaterally on the eye after a certain amount of air pressure was given to that eye's cornea and recorded by electromyography.
2. The frequency of developing "blink reflex" was either increased or decreased following the wearing of a contact lens.
3. In EEG there developed arousal reaction following a 100 c/s stimulation on reticular formation (RF), nucleus centrum medianum (CM) and nucleus ventralis anterior (VA), recruiting response following an 8 c/s stimulation on CM and VA, and spike and wave following a 3 c/s stimulation on CM and VA. Such development was always accompanied with bilateral blinking.
4. The freq u ency of blinking developing due to central nerve stimuli either increased or decreased following the wearing of a contact lens.
5. Three types of blinking developed following c entral nerve stimuli, T type which was continuous for a certain duration at certain intervals in the post -stimulation stage, P type which was repetitious during and immediately after stimulation, and TP type which was a mixed form. Generally T type often developed in association with spike and wave, P and TP type tended to develop in association with recruiting response and arousal reaction.
6. Th e types of evoked muscular discharge following central nerve stimuli maintained almost a parallel relationship with the types of blinking.
7. A comparative study of the effects of barbiturate, myanesin and chlorpromazine on "blink reflex" and flexion reflex revealed that both reflexes were of the same origin of mechanism.
8. Experimentally barbiturate, myanesin and chlorpromazine worked differently on blinking due to central nerve stimuli and "blink reflex". It was assumed that these two kind of blink were of different origin.
9. The inhibitory action of barbitura te, myanesin and chlorpromazine on blinking due to central nerve stimuli showed a parallel relationship with their inhibitory acti on on uusal reaction, recruiting response and evoked muscular discharge.
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