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Volume 53 (2001)
- Issue 2-4 Pages 125-
Volume 53, Issue 2-4
Displaying 1-5 of 5 articles from this issue
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Yasuhiro Isami, Toshihiro Ikuma, Mineo Okamoto, Shunpei Mizutani, Miki ...2001 Volume 53 Issue 2-4 Pages 125-129
Published: December 20, 2001
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSBackground; Creatinine (Cr) is supposed to be uniformly distributed in body fluid, as is the case with urea nitrogen (UN). We calculated the normalized dialyser serum Cr (S-Cr) clearnce (Kt/Vcr), time averaged concentration of S-Cr (TACcr), and creatinine generation rate per body weight (gCr) on the basis of creatinine kinetics instead of urea k inetics and assessed whether these parameters would provide useful new indicators for optimal dialysis. Methods; Blood UN (BUN) and S-Cr values were measured in 13 hemodialysis patients immediately before and after a session of dialysis and immediately before the next session. Based on these measurements, the new indicators were calculated and compared with the conventional indicators [normalized dialyser urea clearnce (Kt/Vurea), time averaged concentration of BUN (TACBUN), protein catabolic rate (per) ]. Results; There was a significant positive correlation (r = 0.95, P<0.001) between Kt/Vcr (1.05 ± 0.15) and Kt/Vurea, and between TACcr (9.9 < 1.6) and TACBUN (r = 0.85, P <0.001). The gCr (27.9 < 5.5mg/kg/day) also correlated with per. Conclusion; Kt/Vcr and TACcr can be new indicators for optimal dialysis. The gCr may serve as a comprehensive indicator of nutritional conditions in hemodialysis patients.View full abstractDownload PDF (804K) -
Shigeo Kyutoku, Koji Yasui, Moritaka Shima, Masahito Satoh2001 Volume 53 Issue 2-4 Pages 130-134
Published: December 20, 2001
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSEpignathus, rare congenital tumor is generally known as an oropharyngeal mass, often resulting air way obstruction following birth. We present a case with epignathus combined with cleft palate; a female infant who was born in 37weeks of pregnancy by Casesarian operation and underwent an excision in her first day of life because of respiratory distress by the tumor.View full abstractDownload PDF (1940K) -
Farjana Jahan Fattah, Masayuki Morita, Satoshi Mizutani, Kazi Riaz Fat ...2001 Volume 53 Issue 2-4 Pages 135-140
Published: December 20, 2001
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSWe sequenced an E. coil 6.6 kb fragment by using in vitro transposition reaction of Tn3. Tn3 inserted randomly into the target plasmid and the ends of the transposon can be used as movable primer sites. Our selection system eliminates cointegrates and leaves only the simple insertions which makes it suitable for sequencing. We applied both the shotgun method and the ordered method in order to compare them. The shotgun method required more clones but produced the total sequence quickly by the use of a suitable software such as DNAMAN. Moreover, the redundancy of sequencing involved in shotgun method has the advantage of making the result more reliable. The ordered method requires information about the order and separation of transposon insertion sites in different clones in order to select the plasmids to be used for sequencing, but resulted in minimum redundancy. However, the amount of preliminary wo rk required in the ordered method before actual sequencing far outweighs the benefit in the reduction in the number of clones necessary to be sequenced. The E. colt: sequence we obtained turned out to be a recombinant between the standard database sequence (AE000441) and another sequence published by Jensen's group (X00781) within the rph gene.View full abstractDownload PDF (970K) -
Yoichiro Uchida, Hiroaki Kitade, Masaki Kaibori, Soichiro Takai, Yusai ...2001 Volume 53 Issue 2-4 Pages 141-147
Published: December 20, 2001
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSThe Groshong catheter is a central venous catheter that can be inserted through the peripheral veins. In this study, we reviewed our experience with the use of this apparatus. The subjects comprised 21cases (total of 24 operations) between April 1998 and June 2000. The patients ranged in age from 18 to 87 years (mean 64 years) and included 12 males and 9 females. Six operations were performed for the treatment of gastric cancers,3 for colon cancers,3 for pancreatic cancers, and 9 for other diseases. The purpose for the use of the Groshong catheter was the administration of high calorie parenteral nutrition in 19 cases, chemotherapy in 4 cases, and another purpose in one case. The duration of device implantation ranged from 3 to 51 days, with an average of 18.9 days. There were 16 cases in which the catheter was removed prior to the termination of therapy. The reasons for removal included pyrogenic reactions in 10 cases, phlebitis in 4 cases, and other reasons in 2 cases. There was a high incidence of catheter removal before the termination of therapy, since early removal is our general policy when there are pyrogenic reactions during the placement of a central venous catheter. Apart from these minor complications, the Groshong catheter did not cause any other serious complications, and was technically easy to insert. Therefore, we concluded that this apparatus is very beneficial for the purposes of the continuous administration of carcinostatics or high calorie parenteral nutrition in cases there was no need to measure the central venous pressure.View full abstractDownload PDF (1693K) -
Kazi Riaz Fattah, Satoshi Mizutani, Fariana Jahan Fattah, Yoshinobu Su ...2001 Volume 53 Issue 2-4 Pages 148-151
Published: December 20, 2001
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSIn the N antitermination system of bacteriophage lambda and related phages, the BoxB of the nut site interacts with the N protein to form an antitermination complex. Arginine-rich sequences in the N-proximal region of these proteins in phage lambda, P22 and P21 have been assigned as the recognition sequences of these phages. An arginine-rich motif very similar to that of P22 N protein has been found in the N protein of phage HK97 and the toxin-converting phages 933W and H-19B, which we suggest to be the recognition sequence of these N proteins because these three phages have a BoxB loop sequence identical with that of P22. We also found a slightly different, but similarly located arginine-rich sequence in phage VT2-Sa N protein, which we suggest is the recognition sequence of the N protein for this phage. This is consistent with the fact that its BoxB loop is different from the other three phages.View full abstractDownload PDF (543K)
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