All issues
Volume 58 (2006)
- Issue 2-4 Pages 153-
Volume 58, Issue 2-4
Displaying 1-5 of 5 articles from this issue
- |<
- <
- 1
- >
- >|
-
Kazuko NAKAO, Ryuichi MATSUZAKI, Yusaku AMAYA, Shin-ichi KYUHOU, Hisae ...2006 Volume 58 Issue 2-4 Pages 153-162
Published: December 30, 2006
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSRecently we recorded readiness potentials for self-paced movements of various body parts in the posterior parietal cortex (PPC) as well as in the motor cortex. To study involvement of the PPC in muscle force control, we analyzed readiness potentials recorded by electrodes implanted in many cortical areas in two monkeys performing self-paced hand movements to lift a lever either with or without additional load. Readiness potentials in the PPC increased in amplitude as required muscle force in hand movements increased as well as in the premotor, motor and somatosensory cortices. Further, we investigated in which body part the PPC activates muscles and how easily. Electromyograms induced in muscles in various body parts after cortical stimulation in three monkeys were analyzed. Stimulation of areas 5 and 7 produced a somatotopic pattern in muscle activities, as in the motor cortex. Stimulus intensity in area 5 for inducing muscle activity was slightly higher than that in the motor cortex, while much higher stimulus intensity was required in area 7. Taken together, preparative muscle force control was found in the PPC, which could activate muscles in various body parts, similar to the motor cortex but with a higher threshold. These suggest that the PPC plays important roles in motor functions.View full abstractDownload PDF (2227K) -
Zhijie QIN, Sandip VYAS, Anthony L. FINK, Jinsong LI, Hiroshi KIHARA2006 Volume 58 Issue 2-4 Pages 163-169
Published: December 30, 2006
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSSubstantial questions remain about the process of protein folding, including whether transient intermediates exist with significantly different secondary structure than the final fold. The src SH3 domain is a highly beta-rich structure with five betastrands. We report here a far-UV circular dichroism investigation of the refolding of His-tagged Src SH3 at subzero temperatures. We observed a transient a-helix-rich intermediate, indicating that the early stages of protein folding can involve the formation of intermediates with very different structures from the final conformation.View full abstractDownload PDF (1089K) -
Masahiko IZUMIKAWA2006 Volume 58 Issue 2-4 Pages 171-177
Published: December 30, 2006
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSDownload PDF (2846K) -
Takamichi UCHIYAMA, Richard M. ENGELMAN, Nilanjana MAULIK, Dipak K. DA ...2006 Volume 58 Issue 2-4 Pages 178-185
Published: December 30, 2006
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSDownload PDF (2284K) -
Nobuyuki TANIGAWA2006 Volume 58 Issue 2-4 Pages 186-187
Published: December 30, 2006
Released on J-STAGE: February 19, 2013
JOURNAL FREE ACCESSDownload PDF (423K)
- |<
- <
- 1
- >
- >|