From November 24 th 1978 through August 3rd 1979, 1, 000 examinations were carried out with 4 th generation computed body tomography scanner, Delta-scan 2010 at the CBT center of Nippon Medical School Daiichi Hospital.
A statistical review is reported on sex and age distribution. The requisitions on body organs by each department are analyzed. New indication for computed body tomography is discussed. Our technic of whole body second fast scanner tomography as well as contrast enhancement is explained on these cases. Present status of CBT in our department of radiology is evaluated, and perspectives of this modality of examination are discussed. Illustrative cases with Delta-scan 2010 are demonstrated and explained.

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The circulating erythrocytes of Rana catesbeiana tadpole and adult frog were separated into young and old age fractions according to their density by use of the method of Danon et al., in which phthalate esters are used as a separating liquid, and also by use of Murphy's technique.
The density-separated tadpole and adult frog erythrocytes were subjected to measurements of [¹⁴C] leucine incorporating activity into hemoglobin and to differential determination of tadpole and adult frog hemoglobins with immunoprecipitation. Change-over from tadpole to adult frog erythrocytes during metamorphosis was investigated in relation to the transition of hemoglobin. The results obtained are as follows;
1) The tadpole and adult frog erythrocytes are distributed in the density ranging from 1.0850 to 1.1000 and from 1.0925 to 1.1075, respectively.
2) At the onset of metamorphosis, the tadpole erythrocytes become heavier.
3) At the metamorphic climax, the circulating erythrocytes are separated into two groups differing in their density from one another. The less dense cells contain the adult frog hemoglobin and are highly active to synthesize the hemoglobin molecule, whereas the more dense cells contain the tadpole hemoglobin and show a low biosynthetic activity.
4) The transition from tadpole to adult frog hemoglobin occurs in parallel with the changeover from tadpole to adult frog erythrocytes during metamorphosis.

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It has been known that several RNases occur in various tissues of vertebrates, although the role in the RNA metabolism of individual RNase is obscure. To study a possible mechanism involved in the regulation of RNase activity in the muscle during bullfrog metamorphosis, it was attempted to characterize a RNase from bullfrog muscle showing its activity in neutral region.
The neutral RNase in the cytosol fraction from bullfrog muscle occurs in two forms, one is a free form and the other a complex (latent form) of the RNase and its inhibitor. As compared with those of bullfrog liver, it was found that in the muscle cytosol fraction the greater part of the RNase is present as the complex and an excess amount of the RNase inhibitor as a free form. The partially purified RNase from the muscle cytosol fraction resembled to that of the liver in enzymatic properties.

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The recent progress in endoscopic examinations, especially in the technique of biopsy under direct vision has remarkably increased the accuracy of the diagnosis of gastric lesions. However, a complete histological diagnosis cannot be expected for every case. I have examined 954 patients with 980 lesions which required correct histological diagnosis in the past twelve years. 73 out of these 980 lesions were false negative in forceps biopsy (7.4%). Most of these false negative cases were submucosal tumors including sarcomas whose lesions are characteristically found in submucous layer. In a few other cases the following cause would be considered; biopsy forceps might not reach the lesional parts, and the specimens were not available for proper pathological diagnosis.
To improve the accuracy of the histological diagnosis in these false negative cases, a combined technique of forceps biopsy and mucosal cut with electrocoagulation, polypectomy, and the newly devised needle biopsy were applied with favorable results. The latter biopsy needle proved itself to be especially useful as a means of biopsy for submucosal tumor, capable of getting desirable specimens more easily.

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esophagography with barium meal and endoscopic examination are widely used for the diagnosis of esophageal disturbances. Besides them, angiographic examination has recently attracted the interesting discussion of this field, esophageal arteriography is expected to be of importance in investigating the neoplastic extension towards the outside, infiltration to the adjacent organs and metastatic regions of malignancies.
Upon vessels supplying the thoracic and abdominal esophagi, however, little has been written about the pathological changes in esophageal diseases, particularly in cancer.
A newly shaped catheter was desinged by authors and esophageal arteriography was performed with it on 50 cases. The arteriographic findings in esophageal cancer and angioscintigraphies by direct intraarterial injection of¹³¹I-MAA or ^99mTc-MAA were investigated to get the following knowledges.
1. The success rate of selective arteriography by using the improved catheter was 93.9% in bronchial artery, 90.9% in proper esophageal artery and 100% in coeliac artery.
2. Out of 46 cases of proper esophageal artery, 44 occured from a left anterior surface. one from a centre and one from a right anterior surface of the descending aorta. All arteries originate at a level of Th 7-Th 9.
3. Subtraction technique was effective to visualize the vascular change at periphery and cineradiography was useful to observe the dynamic status.
4. In cancer of the thoracic esophagus, hypervascularity, tumour stain, irregularity of vessels and arteriovenous shunt were observed in almost the same frequency in both proper esophageal and bronchial arteriographies. On the other hand, these findings were not remarkable in the coeliac artery field. In esophageal cancer localized in at least more than two segments, arteries related showed the changes according to the anatomical position of the disease.
5. All arteriographic findings excluding arteriovenous shunt were observed in the frequency of more than 90%, particularly as high rate as 96.0% so far as hypervascularity concerned. It is, therefore, concluded that esophageal cancer arteriographically belongs to the category of hypervascularity.
6. Angioscintigraphy supported well the arteriography in getting the further information of the morphology of tumour. Macroaggregated albumin was recognized to stay up to 72 hours at the neoplastic region.
The clinical value of esophageal arteriography in both diagnostic and some therapeutic radiology were discussed.

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We have employed a statistical study on a total of 1, 161 cases during the ten years from July 15, 1966 to July 14, 1976. Of which 498 (43%) were manic-depressive illness, 200 (17%) were schizophrenia and 120 (10%) were psychogenic reaction.
There were no remarkable annual change in diagnostic distribution.
The age distribution showed the peak at the age between 20 and 30. As for manic-depressive illness, however, involutional melancholia aged between 40 and 50 was most numerous.
As for regional distribution, patients from Bunkyo district of Metropolitan Tokyo nearby our clinic were most numerous.
In our clinic, somatic treatments such as psychopharmacotherapy and electric convulsive therapy (ECT) have mainly been used for psychiatric patients effectively.

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