Journal of Nippon Medical School
Online ISSN : 1884-0108
Print ISSN : 0048-0444
ISSN-L : 0048-0444
Search
Advanced search
OR
Browse
Search
Volume 62, Issue 6
Displaying 1-15 of 15 articles from this issue
Show all abstracts
    • |<
    • <
    • 1
    • >
    • >|
  • Reconstructive surgery using the flaps pedicled by rectus abdominis muscle or deep inferior epigastric artery
    Hiko Hyakusoku
    1995 Volume 62 Issue 6 Pages 567-573
    Published: December 15, 1995
    Released on J-STAGE: March 01, 2010
    DOIhttps://doi.org/10.1272/jnms1923.62.567
    JOURNAL FREE ACCESS
    Download PDF (4811K)
  • Long-term results in valve replacement with Björk-Shiley prosthesis
    Analysis of life expectancy by relative survival rate
    Noriyoshi Kutsukata
    1995 Volume 62 Issue 6 Pages 574-587
    Published: December 15, 1995
    Released on J-STAGE: March 01, 2010
    DOIhttps://doi.org/10.1272/jnms1923.62.574
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    Using the U.S. STS guidelines, I analyzed the results of 389 patients who underwent Bjöork-Shiley valve (BS valve) replacement at Nippon Medical School over the past 15 years. In addition, I calculated their relative survival rates using the Japanese Abridged Life Table and objectively determined the treatment effects by taking into account the patients' postoperative life expectancy. There were 201 male and 188 female patients, whose mean age at the time of surgery was 52±12 years. Of these, 151 patients underwent aortic valve replacement (AVR); 185 had mitral valve replacement (MVR); and 53, aortic and mitral valve replacement (DVR). Convexo-Concave models (CC models) were used in 94 patients, and Monosrut models (MS models) in 295. Their cumulative follow-up was 2006 patient-years and their average observation period was 5.2±3.6 years (complete follow-up in 98% of cases). A total of 32 patients suffered an early death, while 36 suffered a late death. At 10 years after surgery, the actual survival rates were 80.3% for patients who underwent AVR; 81.9% for MVR; and 70.7% for DVR, indicating no significant differences among the three groups (NS). Meanwhile, the relative survival rates at 10 years after surgery were 88.6% for patients who underwent AVR; 88.2% for MVR; and 75.4% for DVR, indicating that AVR was superior to DVR (p<0.001), with MVR rated between the two. No significant differences were seen among the three groups with respect to the occurrence rate of valve-related complications. The most frequent complications' thromboembolism occurred at a rate of 2.29%/patient-years overall. Strut fractures occurred in two patients using the CC models (0.25%/patient-years), but there were no strut fractures among those using the MS models. While the effect of atrial fibrillation on the subjects' life prognoses was unclear (NS), patients often developed complications related to artificial valves (p<0.025), and their life prognoses were inferior to those of patients with sinus rhythm. Survivors reported marked improvements in their quality of life, and their late survival rates were satisfactory. However, their life expectancy was inferior to that of the normal population.
    View full abstract
    Download PDF (2420K)
  • Analysis of duodenal bile acids in patients with colorectal tumors and control subjects
    Fumihiko Taguchi
    1995 Volume 62 Issue 6 Pages 588-595
    Published: December 15, 1995
    Released on J-STAGE: March 01, 2010
    DOIhttps://doi.org/10.1272/jnms1923.62.588
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    Bile acids are believed to play a role in the etiology of colorectal cancer. To investigate a possible relationship between bile acids and colorectal tumors, duodenal bile acids were analyzed in 18 patients with colorectal adenomas, 18 patients with colorectal carcinoma and 18 control subjects. Using high performance liquid chromatography and immobilized 3 α-hydroxysteroid dehydrogenase in column form, significant increases in the proportion of chenodeoxycholic acid and significant decreases in the proportion of deoxycholic acid and lithocholic acid were found in the bile of patients with colorectal adenoma or carcinoma compared with the control subjects. The data support the concept that bile acids have a role to play in the development of large bowel tumors.
    View full abstract
    Download PDF (1457K)
  • The influence of methionine and its metabolites on the progression of atherosclerosis in rabbits
    Junzoh Koyama
    1995 Volume 62 Issue 6 Pages 596-604
    Published: December 15, 1995
    Released on J-STAGE: March 01, 2010
    DOIhttps://doi.org/10.1272/jnms1923.62.596
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    The effects of a high level of methionine on the changes of lipid and amino acid metabolism were investigated. Eighteen New Zealand White rabbits were divided into three groups; a methionine group, which was fed a diet supplemented with 3%D, L-methionine, a Cholesterol+Methionine group, which was fed a 3% D, L-methionine and a 0.2% cholesterol diet, and a Cholesterol group which was fed a 0.2% cholesterol diet for 22 weeks.
    The plasma triglyceride, cholesterol, homocysteine, cysteine and serum SO42-levels were measured and compared. On the first and the final day of the experiment, lipid peroxide levels in blood smaples were also measured.
    We found that the Methionine group and the Cholesterol+Methionine group showed elevated levels of plasma triglyceride, cholesterol, homocysteine, cysteine, serum SO42-and lipid peroxide compared with the Cholesterol group. More prominent fat deposits in the aorta were observed in the Methionine group and the Cholesterol+Methionine group than in the Cholesterol group.
    Our results indicated that the interaction of cholesterol with methionine or its derivatives plays a role in the progression of atherosclerosis.
    View full abstract
    Download PDF (3187K)
  • Regional cerebral blood flow in status epileptics measured by single photon emission computed tomography (SPECT)
    Hajime Ichiseki, Makoto Hamamoto, Tokuzo Miyazaki, Akiro Terashi
    1995 Volume 62 Issue 6 Pages 605-614
    Published: December 15, 1995
    Released on J-STAGE: March 01, 2010
    DOIhttps://doi.org/10.1272/jnms1923.62.605
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    Status epileptics (SE) due to a cerebral vascular accident can cause a change for the worse in the quality of life of patients.
    We have performed single photon emission computed tomography (SPECT) with 99m Tc-hexamethylpropylene amineoxim (HM-PAO) to evaluate regional cerebral blood flow (rCBF) in SE caused by a cerebral vascular accident. In addition, we have discussed the neurophysiology of SE based on the SPECT findings.
    A total of sixteen patients (5 males and 11 females, average age; 78.2 years old) with SE who were suffering from prolonged consciousness disturbance were investigated.
    When SPECT was performed in the ictal state, there was a remarkable increase in Radio Isotope (RI) uptake at the focus which correlated well with EEG findings. However, in other cortical regions, basal ganglia and thalamus, there was a relatively demonstrated decrease in RI uptake compared with that of the focus.
    Additionally in the interictal state, we found a decrease in RI uptake in the epileptic foci and normal recovery of the RI uptake level in other cerebral regions.
    We speculate that these characteristic patterns of cerebral blood flow distribution shown by SPECT scans in the ictal state reflect the state of consciousness disturbance due to SE.
    In general, in the elderly, it is difficult to make a differential diagnosis between prolonged consciousness disturbance due to nonconvulsive SE and other diseases such as cardiovascular, dehydration, metabolic disorder, etc.
    Nevertheless, nonconvulsive SE causes diffuse cell loss and irreversible brain damage. Therefore the elderly who have suffered from prolonged consciousness disturbance due to SE need an exact diagnosis and immediate medical treatment. When we diagnose a nonconvulsive SE, the characteristic findings of SPECT scans in the ictal state are very clear and useful.
    In conclusion, SPECT is a very simple and non-invasive method that demonstrates abnormalities of brain function exactly. Therefore, we should perform not only EEG but also SPECT scans when making a diagnosis of SE.
    View full abstract
    Download PDF (3203K)
  • Writing a manuscript in English
    Koichi Tamura
    1995 Volume 62 Issue 6 Pages 615-619
    Published: December 15, 1995
    Released on J-STAGE: March 01, 2010
    DOIhttps://doi.org/10.1272/jnms1923.62.615
    JOURNAL FREE ACCESS
    Download PDF (898K)
  • [title in Japanese]
    [in Japanese], [in Japanese], [in Japanese]
    1995 Volume 62 Issue 6 Pages 620
    Published: December 15, 1995
    Released on J-STAGE: March 01, 2010
    DOIhttps://doi.org/10.1272/jnms1923.62.620
    JOURNAL FREE ACCESS
    Download PDF (189K)
  • [title in Japanese]
    [in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
    1995 Volume 62 Issue 6 Pages 625-636
    Published: December 15, 1995
    Released on J-STAGE: March 01, 2010
    DOIhttps://doi.org/10.1272/jnms1923.62.625
    JOURNAL FREE ACCESS
    Download PDF (2524K)
  • [title in Japanese]
    [in Japanese], [in Japanese]
    1995 Volume 62 Issue 6 Pages 637-641
    Published: December 15, 1995
    Released on J-STAGE: March 01, 2010
    DOIhttps://doi.org/10.1272/jnms1923.62.637
    JOURNAL FREE ACCESS
    Download PDF (927K)
  • [title in Japanese]
    1995 Volume 62 Issue 6 Pages 642-650
    Published: December 15, 1995
    Released on J-STAGE: March 01, 2010
    DOIhttps://doi.org/10.1272/jnms1923.62.642
    JOURNAL FREE ACCESS
    Download PDF (2321K)
  • [title in Japanese]
    1995 Volume 62 Issue 6 Pages 651-667
    Published: December 15, 1995
    Released on J-STAGE: March 01, 2010
    DOIhttps://doi.org/10.1272/jnms1923.62.651
    JOURNAL FREE ACCESS
    Download PDF (4361K)
  • [title in Japanese]
    1995 Volume 62 Issue 6 Pages 667-677
    Published: December 15, 1995
    Released on J-STAGE: March 01, 2010
    DOIhttps://doi.org/10.1272/jnms1923.62.667
    JOURNAL FREE ACCESS
    Download PDF (2861K)
  • [title in Japanese]
    1995 Volume 62 Issue 6 Pages 678-691
    Published: December 15, 1995
    Released on J-STAGE: March 01, 2010
    DOIhttps://doi.org/10.1272/jnms1923.62.678
    JOURNAL FREE ACCESS
    Download PDF (3579K)
  • [title in Japanese]
    1995 Volume 62 Issue 6 Pages 692-706
    Published: December 15, 1995
    Released on J-STAGE: March 01, 2010
    DOIhttps://doi.org/10.1272/jnms1923.62.692
    JOURNAL FREE ACCESS
    Download PDF (3850K)
  • [title in Japanese]
    1995 Volume 62 Issue 6 Pages 707-716
    Published: December 15, 1995
    Released on J-STAGE: March 01, 2010
    DOIhttps://doi.org/10.1272/jnms1923.62.707
    JOURNAL FREE ACCESS
    Download PDF (2404K)
    • |<
    • <
    • 1
    • >
    • >|
feedback
 Top