Cholinesterase reactivator PAM (Pralidoxime) is used in the treatment of organophosphates poisoning with anticholinergic agent atropine. However, some reports demonstrated recently that PAM has inefficacy in some cases of so-called low toxicity organophosphates poisoning. So, to atempt to discuss the efficacy of PAM in clinical treatment, we searched for the case reports of these poisoning by JOIS. In this time, we compared with the specificity of each data bases and presented some examples in this on-line information retrieval.
The necessity of a retrieval aid solely for review literature is recognized according to the former study on existing bibliographic databases. The project to compile and publish the index journal RAMBIOS : Review Articles of Molecular Bioscience as an aid for efficient retrieval of review literature is reported with its background and processes of tasks. Some findings and reaction of users are also introduced from the experience of indexing and computer-aided compilation of GRR : Guide to Recent Reviews in Biophysics, Biochemistry and Molecular Physiology, published as a preliminary edition of RAMBIOS. The on-line retrieval of RAMBIOS database now available is explained lastly, followed by remarks on encouraging researchers to utilize the journal and on the future plan of RAMBIOS.