For exploration of promising intermediates in fine chemical industry, a new method using a computer-aided system for synthesis design, SYNSUP, is presented. The synthesis design system is utilized to generate promising intermediates. The promising intermediates are included in the common intermediates, which have more than one different target compounds.
As compared with the current ongoing chemical process, the facility and validity of the proposed intermediates were evaluated with respect to candidates for new intermediates. Consequently, it was cleared that the extracted intermediates contained not only the reported intermediates but also the new ones. The new tactics is very powerful to find new promising intermediates among various chemical compounds. In addition, the total system including SYNSUP and extraction of common intermediates is automatically executed to a huge amount of chemicals in a computer, although the similar operation is impossible by manual.
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