巻号一覧
71 巻 (1959)
- 12-2 号 p. 8243-
- 12-1 号 p. 7861-
- 11supplement 号 p. 1-
- 11-2 号 p. 7531-
- 11-1 号 p. 7095-
- 10-2 号 p. 6691-
- 10-1 号 p. 6223-
- 9-2 号 p. 5773-
- 9-1 号 p. 5405-
- 8-2 号 p. 4993-
- 8-1 号 p. 4515-
- 7-2 号 p. 4069-
- 7-1 号 p. 3623-
- 6-2 号 p. 3149-
- 6-1 号 p. 2783-
- 5-2 号 p. 2423-
- 5-1 号 p. 1989-
- 4-2 号 p. 1655-
- 4-1 号 p. 1145-
- 3supplement-2 号 p. 1-
- 3supplement-1 号 p. 1-
- 3-2 号 p. 1145-
- 3-1 号 p. 691-
- 2-2 号 p. 691-
- 2-1 号 p. 323-
- 1 号 p. 1-
前身誌
102 巻, 3-4 号
選択された号の論文の26件中1～26を表示しています
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何川 凉, 守屋 文夫, 中井 三代子, 橋本 良明1990 年 102 巻 3-4 号 p. 281-285
発行日: 1990年
公開日: 2009/08/24
ジャーナル フリーFrom August 1978 to December 1989, 85 paternity testings were performed in our department.
In 49 cases, each man was accused to be the father of an illegitimate child. In 24 cases, each child was accused to be an illegitimate child by the father. In 9 cases, each child was sued for making sure to be a real child of a man.
Paternity was excluded in 15 of the cases.抄録全体を表示PDF形式でダウンロード (242K) -
第1編 三叉神経脊髄路尾側亜核におけるサブスタンスPおよびエンケファリン濃度変動の意義に関する基礎的研究藤原 則章1990 年 102 巻 3-4 号 p. 287-297
発行日: 1990年
公開日: 2009/08/24
ジャーナル フリーわれわれはdeafferentation painの発現あるいは抑制機序についてSP及びENKの果たす役割を調査した.まず予備実験としてSTNの同定ならびにSTNへのこれら両物質の局在を確かめるべくネコ6頭を用いSTNのH. E.染色を行い組織学的同定により同核の解剖学的位置を確認した後,他のネコ6頭を用いPAP変法により組織染色を行い, STNにおけるそれぞれの物質の分布を調べた.この予備実験結果をもとに,ネコ8頭を用いGGを切断することによりdeafferentation painモデルネコを作成したうえでSTN中の両物質の濃度変動を調べた.また, Freund's adjuvantをネコ一側顔面に注入することによりexcess painモデルネコ6頭を作成し,同様にSTN中の濃度を調査した.
その結果,まずdeafferentationモデルネコではSTN中SPに著明な低下が認められた.これは三叉神経の神経伝達物質としてのSPの役割からすれば当然の結果と考えられた.またexcess painモデルネコでのSPの上昇は, SPの痛みの神経伝達物質としての関与を示す結果であろうと考えられた.次に, deafferentationモデルネコにおいてはENKの濃度変化は認められなかった.しかし, STNのオピエートは上位中枢の支配下にかならずしもあるとはいえず, propriospinalに機能している可能性も否定できないと思われた.最後にexcess painモデルネコではENKは変化がみられなかった.これはENKの代謝速度が速やかなためその濃度変化を捕らえにくかったものと考えられるとともに,痛みの自動抑制機構としてはENKのみならずドーパミン,ノルエピネフリンなどのモノアミンの関与を考慮すべきことが示唆された.
稿を終えるに臨み,終始御懇切なる指導を賜った岡山大学脳神経外科西本詮教授,ならびに本研究の直接の御指導をいただいた岡山労災病院難波真平先生に深い感謝の意を表します.抄録全体を表示PDF形式でダウンロード (4683K) -
第2編 頑痛患者に於ける髄液中β-endorphinおよびmonoamine代謝産物 -中枢神経系の電気刺激前後に於ける濃度変動について-藤原 則章1990 年 102 巻 3-4 号 p. 299-308
発行日: 1990年
公開日: 2009/08/24
ジャーナル フリーThe concentration of β-endorphin-immunoreactivity (β-END-IR) and monoamine metabolites which are 3-methoxy-4-hydroxy-phenylglycol (MHPG), homovanillic acid (HVA) and 5-hydroxyindole acetic acid (5-HIAA) were measured in cerebrospinal fluid (CSF) of patients with intractable pain to estimate the participation of these substances in the mechanism of intractable pain.
The amount of β-END-IR and monoamine metabolites was measured with radioimmunoassay and HPLC (high performance liquid chromatography), respectively.
Eight cases of intractable pain were treated with implantation of the stimulating electrode for pain relief. This treatment was performed in 2 ways, deep brain stimulation (DBS) done on 6 cases and spinal dorsal column stimulation (DCS) on 2 cases. The concentrations of β-END-IR and monoamine metabolites were also estimated before and after the stimulation. No patient treated with DBS showed the elevation of β-END-IR or monoamine metabolites after the stimulation, except for one patient who showed significant increase of monoamine metabolites accompanying excellent pain relief by the stimulation. On the other hand, the two patients treated with DCS indicated significant elevation of β-END-IR as well as monoamine metabolites.
Thus, both β-END and monoamines could play an important role in DCS, and that monoamine could be involved in DBS for pain relief.抄録全体を表示PDF形式でダウンロード (643K) -
河田 真作1990 年 102 巻 3-4 号 p. 309-318
発行日: 1990年
公開日: 2009/08/24
ジャーナル フリーThe histological appearance of reperfusion injury is pulmonary edema associated with leukocyte aggregation in the vessels. We hypothesized that leukocytes play an important role in reperfusion injury and that leukocyte depletion could prevent it. Eighteen white male rabbits were divided into 3 groups. After extirpation, the lungs in group 1 were not preserved, and were reperfused with whole blood that was taken from other white rabbits. In groups 2 and 3, after flushing with 100 ml of modified Collins' solution, the lungs were preserved in the same solution for 6 hours at 4°C. Lungs in group 2 were then reperfused with whole blood while lungs in group 3 were reperfused with leukocyte-depleted blood. We measured the water content of the lung to determine the degree of pulmonary damage, the malondialdehyde (MDA) levels in reperfused blood and lung tissue, the complement activity, and examined the histological findings. Group 2 showed severe pulmonary edema histologically, and a significantly higher water content and MDA level than the other groups. There was no significant difference in complement activity between the 3 groups. Leukocyte depletion was effective in reducing reperfusion injury of the lung.抄録全体を表示PDF形式でダウンロード (6220K) -
蓮井 雅浩, 向原 直木, 丸谷 盛雄, 大林 直嗣, 白木 照夫, 内田 真司, 井原 敬子, 戸川 潤一郎, 山成 洋, 日名 一誠, ...1990 年 102 巻 3-4 号 p. 319-323
発行日: 1990年
公開日: 2009/08/24
ジャーナル フリーWe reported a case of primary cardiac lipoma in a 74-year-old woman who had a 23-year history of cardiomegaly. The chest roentgenogram showed an enlargement of the cardiac silhouette. The electrocardiogram showed slight abnormalities including mild low voltage of R wave in V6 and flat T wave in V5 and V6. M-mode and cross-sectional echocardiography revealed a low echoic mass which mainly situated between left ventricular posterior wall and the pericardium. The left and right ventricular wall motion was not affected. Computed tomography of the heart revealed a large mass backward of the left ventricle and right side of the right atrium. The attenuation values of the mass ranged around-118HU and was compatible to lipoma. We diagnosed as a lipoma of the heart possibly arising from the pericardium. Computed tomography may be of use for a very specific diagnosis of cardiac lipoma.抄録全体を表示PDF形式でダウンロード (3657K) -
新田 浩喜1990 年 102 巻 3-4 号 p. 325-336
発行日: 1990年
公開日: 2009/08/24
ジャーナル フリーDestruction of attachment of the anterior cruciate ligament (ACL) was studied. The tibial attachments of the ACLs from 32 rheumatoid knees taken during total knee replacement were examined by light microscope. Sections of samples were stained with hematoxylin-eosin (H. E.) and peroxidase anti-peroxidase (PAP) methods.
The destructive changes of ligament attachments were degeneration of collagen fibers, disappearance of fibrocartilage zone and mineralized fibrocartilage zone, increase of fibroblast-like cells at the area of ligament insertion, change and disappearance of tide mark, invasion of fibrous granulation tissues, bone trabecular thinning, inflammation of intramedullary space, and proliferation of blood vessels at the ACL with granulation tissues.
Statistical examination of these findings showed that the condition of tide mark is characteristic in destruction of the enthesis of rheumatoid knees.
Calcification and ossification of the enthesis were not observed, and turnover of the enthesis can be very active.
On the other hand, large monocytes and fibroblast-like cells at the area invasived by fibrous granulation tissues have positive staining for lysozyme by PAP method. Monocytes and chondrocytes at the area remained in the fibrocartilage zone and mineralized fibrocartilage zone were positive for S-100 protein.
The present pathological study of the ACL destruction of the rheumatoid knees confirmed that tide mark is very peculiar in the changes of the enthesis. Invasion of the granulation tissues from intramedullary space can also be a cause to destruct the ligament attachment.抄録全体を表示PDF形式でダウンロード (10707K) -
岡田 泰士, 村上 哲英, 根木 哲郎, 福西 勇夫, 堀 泰雄1990 年 102 巻 3-4 号 p. 337-345
発行日: 1990年
公開日: 2009/08/24
ジャーナル フリーThe congenital absence of corpus callosum has been recently found to occur among some mice of the ddN strain in our laboratory. In this experiment, the differences of the visual evoked potentials among the normal corpus callosum, callosal hypogenesis and agenesis in ddN strain mice were investigated. One-Hz- flash stimulations were given on the left eye through a glass fiber connector from the EEG stimulator. Under Nembutal anesthesia, two hundred times of average evoked field potentials were recorded from the contralateral and ipsilateral visual cortices. Electrophysiologically, the normal mice showed complete decussation on the opic chiasm. On the other hand, the complete acallosal mice could be classified into two types, such as those of complete decussation and those of absence of optic chiasm. In the complete decussation of acallosal mice, the latency, peak latency and duration of these potentials from ipsilateral side significantly prolonged, and the amplitude of the potentials extremely diminished. In the absence of optic chiasm of complete acallosal mice, the potentials were obtained only in ipsilateral cortex. After amputation of the corpus callosum in the normal mice, the visual evoked field potential showed similar to acallosal mice. However, in the hypogenesis of corpus callosum, there was no significant difference in the potentials compared with the normal mice.抄録全体を表示PDF形式でダウンロード (2624K) -
妹尾 紳1990 年 102 巻 3-4 号 p. 347-356
発行日: 1990年
公開日: 2009/08/24
ジャーナル フリーThe mechanism by which L-histidine inhibits the methamphetamine (MAP)-induced hyperactivity was examined in mice.
L-histidine (1g/kg, i. p.) significantly reduced the locomotor hyperactivity induced by MAP (1mg/kg, i. p.) in either experiment using Open field or Animex apparatus, although L-histidine did not affect the locomotor activity of control mice. L-histidine elevated brain levels of histamine and tele-methylhistamine. Pretreatment with α-fluoromethylhistidine, a histidine decarboxylase inhibitor, suppressed both behavioral and biochemical effects of L-histidine. Metoprine, a histamine-N-methyltransferase inhibitor, increased brain histamine level and suppressed the MAP-induced locomotor hyperactivity. Although L-histidine (1g/kg) markedly changed brain tyrosine levels, this amino acid alone had no significant influence on the monoamine metabolism. It did not modify the change in the monoamine metabolism induced by MAP (1mg/kg), either. The inhibition by L-histidine of the MAP-induced hyperactivity was observed in the mice pretreated with para-chlorphenylalanine or atropine.
These results suggest that central histaminergic systems may have an inhibitory influence on the MAP-induced locomotor hyperactivity. However, serotonergic and cholinergic mechanisms seem not to be involved in this phenomenon.抄録全体を表示PDF形式でダウンロード (2616K) -
國方 永治1990 年 102 巻 3-4 号 p. 357-364
発行日: 1990年
公開日: 2009/08/24
ジャーナル フリーThe human growth hormone (hGH) in lung cancer was studied immunohistochemically in 160 patients by the PAP method. Thirty-four neoplasm specimens (21.3%) contained hGH-positive tumor cells. Positive reaction for hGH was shown in 19 of 64 squamous cell carcinomas, 13 of 48 adenocarcinomas, 2 of 5 carcinods, and none of 26 small cell carcinomas and 17 large cell carcinomas. The sensitivity for hilar type lung cancer was higher than that for peripheral type (p<0.05). Positive rates for hGH were not affected by age, sex, tumor size, lymph node involvement or postsurgical stage. The survival rate of hGH positive patients was not worse than that of hGH negative.抄録全体を表示PDF形式でダウンロード (2058K) -
第1編 キニノゲンに対するモノクローナル抗体による各ドメインの検索石丸 文彦1990 年 102 巻 3-4 号 p. 365-376
発行日: 1990年
公開日: 2009/08/24
ジャーナル フリーAnalysis of kininogen molecule status in four Japanese families affected with total kininogen deficiency and one Japanese family with isolated high molecular weight kininogen deficiency was performed using an immuoblotting method with monoclonal antibodies to high molecular weight kininogen (HKG H 12, L 7, L 17).
The purified high molecular weight kininogen showed two bands with apparent mot wts of 120, 000 and 105, 000, respectively, and the purified low molecular weight kininogen showed a single band with an apparent mot wt of 60, 000. In normal human plasma, these three bands were also detected. No variant molecule of the kininogens was present in either cases of total kininogen deficiency or isolated high molecular weight kininogen deficiency.抄録全体を表示PDF形式でダウンロード (4704K) -
第2編 キニノゲン遺伝子のSouthern blottingによる検討石丸 文彦1990 年 102 巻 3-4 号 p. 377-389
発行日: 1990年
公開日: 2009/08/24
ジャーナル フリーSouthern blot analysis of genomic DNA was performed after digestion with 14 restiction endonucleases in four Japanese families affected with total kininogen deficiency and one Japanese family with isolated high molecular weight kinioogen deficiency, as well as in 15 normal subjects. The blots were hybridized with a kininogen cDNA probe (phKG36).
In cases of total kininogen deficiency, the kininogen gene appeared to be grossly normal at the level of whole genome Southern blotting, suggesting that there were no major deletions, insertions or rearrangement in the kininogen gene.
In a case of isolated high molecular weight kininogen deficiency, a partial deletion in intron 7 was identified. This deletion might have some influence on the mechanism of alternative splicing.
Restriction fragment length polymorphism was detected with Msp I, but carrier detection in these deficient families was impossible.抄録全体を表示PDF形式でダウンロード (7727K) -
小坂 誠1990 年 102 巻 3-4 号 p. 391-404
発行日: 1990年
公開日: 2009/08/24
ジャーナル フリーThe effects of halothane (H) or enflurane (E) concentration on the circulatory system were studied in dogs. Two hours of halothane or enflurane anesthesia resulted in a linear dose-dependent decrease in circulatory indices inculding: mean arterial pressure (mAP), heart rate (HR), cardiac index (CI) and left ventricular peak dp/dt/IP (peak dp/dt/IP). Systemic vascular resistance (SVR) did not change during either anesthesias. The correlations between the percent change of circulatory indices and the logarithm of the blood anesthetic concentrations were expressed by correlation coefficients (r): mAP, r=-0.718 (H), and -0.650 (E); HR, r=-0.329 (H), and -0.352 (E); CI, =-0.597 (H), and -0.596 (E); SVR, r=-0.161 (H), and -0.030 (E); peak bp/dt/IP, r=-0.708 (H), and -0.871 (E). Using several indices of anesthetic depth including MAC, MAC-EI and MAC-BAR, the percent change of mAP, CI and peak dp/dt/IP were calculated at the same anesthetic depth using halothane or enflurane. These results indicated that enflurane depressed these circulatory indices more than halothane. These defferences were: mAP, 14.51±1.46%; CI, 8.14±1.86%; peak dp/dt/IP, 7.38±3.95% (mean±SD). These results, indicate that the depression of circulatory indices at the same anesthetic depth could be expressed by numerical values.抄録全体を表示PDF形式でダウンロード (7950K) -
清水 義央1990 年 102 巻 3-4 号 p. 405-417
発行日: 1990年
公開日: 2009/08/24
ジャーナル フリーThe CNS action of methylguanidine (MGua) was investigated in male S. D. rats. The effects of a GABA-agonist and anticonvulsants on the MGua-induced EEG changes were studied. Several min after an intraventricular injection of 10 μl of a MGua solution (100 mM), rats displayed running fits, tonic- and clonic-convulsion with myoclonic twitching accompanied by polyspikes and spike bursts in the EEG. Diazepam (DZP) (10mg/kg, i. p.) inhibited the convulsive activity, but ethosuximide (ESM) (200mg/kg, i. p.) showed no effect.
Sporadic spike discharges began 2-10 min after MGua (1 μmol) application to the pia mater of the sensorimotor cortex, and thereafter, a recurrent ictal seizure pattern (ISP) was induced. The ISPs were suppressed by DZP (10mg/kg) and phenobarbital (PB) (20mg/kg), injected after the completion of ISPs induced by MGua. Spike discharges were not induced by the application of MGua together with muscimol (50nmol), although muscimol did not suppress the ISPs following their completion. Intraperitoneal injection of either ESM (50-200mg/kg), valproate (200mg/kg) or phenytoin (25 mg/kg), after the completion of ISPs, did not affect the ISPs.
These findings suggest that GABAA receptors might participate in the induction mechanism of MGua-induced seizure activities, and that DZP and PB receptors might a play role in the mechanism which suppresses MGua-induced Seizures.抄録全体を表示PDF形式でダウンロード (854K) -
戸田 洋子1990 年 102 巻 3-4 号 p. 419-434
発行日: 1990年
公開日: 2009/08/24
ジャーナル フリーThe effect of guanidinoethanesulfonic acid (amidino-taurine, GES) on electrocorticograms (ECoG) and the effects of a 4-aminobutanoic acid (GABA)-agonist and anticonvulsants on the GES-induced ECoG changes were studied. Sporadic spike discharges began 2-5 min after GES (1 μ mol) application to the pia mater of the sensorimotor cortex of a rat with a frequency of 5-10 spike discharges/min. Spike discharges in the ECoG of the opposite cerebral hemisphere were observed 60 min after the onset of the spike discharges. The spike discharges lasted until the end of recording after 3 h.
The GES-induced spike discharges were completely suppressed with the supplementation of taurine (1-3 μ mol) on the pia mater following the completion of the spike discharges. GABA (1 μ mol) and its agonists, (3 R)-(-)-4-amino-3-hydroxybutanoic acid and muscimol (10 nmol) when applied topically, also suppressed the GES-induced spike discharges. While diazepam (DZP) (10 mg/kg, i. p.), which acts as a functional GABA-agonist, showed suppressive effects on the GES-induced spike discharges following their completion, phenobarbital (PB) (20 mg/kg, i. p.), which also acts as a functional GABA-agonist, increased the frequency and voltage of spike discharges. While ethosuximide (100 mg/kg, i. p.) showed weak suppressive effects on spike discharges, intraperitoneal injection of either valproate (200 mg/kg) or phenytoin (25 mg/kg) did not affect them.
These findings suggest that neurotransmission or neuromodulatory effects of taurine might participate in the induction mechanism of GES-induced seizure activities, and that GABA and DZP receptors might play a role in the mechanism which suppresses GES-induced seizures.抄録全体を表示PDF形式でダウンロード (923K) -
和気 幹子1990 年 102 巻 3-4 号 p. 435-452
発行日: 1990年
公開日: 2009/08/24
ジャーナル フリーSix adult dogs were anesthetized by deep hypothermia with a combination high dose fentanyl and PGE1 (F group). The circulatory system and blood catecholamine concentration were determined. Another 6 adult dogs were anesthetized by deep hypothermia with a combination ether and PEG1 (E group) for a comparison with the F group.
Before cooling under anesthesia, the PAP, PVRI and Pp/Ps showed a significant difference in the E group. During cooling, the MAP was 74% and 56% of the control values in the F and E groups, respectively and there were significant differences between the F and E groups. The peak dp/dt/IP was significantly different between the F and E groups at the lowest temperature (46% and 27% of the conrol values, respectively). The CI was 34% and 25% of control values at the lowest temperature in both groups.
EP or NE did not significantly increase during cooling or rewarming in the F group. The EP had a tendency to increase during rewarming and NE significantly increased in comparison with the control values during cooling and warming in the E group. Combination anesthesia with high dose fentanyl and PGE1 inhibits the circulatory systems to a lesser degree, resulting in easier maintenance of the circulatory system. This combination system is also more stable than that with ether and PGE1 or with ether and TFP.抄録全体を表示PDF形式でダウンロード (1157K) -
河上 雄之介1990 年 102 巻 3-4 号 p. 453-463
発行日: 1990年
公開日: 2009/08/24
ジャーナル フリーThe effect of iron ion injection on acetylcholine (ACh) turnover was studied in the cerebral cortex of male Sprague-Dawley rats. Rats were divided into 3 groups: rats of the Fe-group were injected with 500 nmol of Fe3+ in the left sensorimotor cortex, rats of the HCl-group were injected with HCl-acidified saline (pH 1.8) in the left sensorimotor cortex, and a shamoperated group acted as a control (Sham-group).
On both sides of the cortex, the choline acetyltransferase (CAT) activity of the HCI- and Fe-groups decreased 30 min after, increased 6h after, and then decreased 24h after the injection compared with the activity of the Sham-group. A no time was there any difference between the CAT activities of the HCl- and Fe-groups. On both sides of the cortex, the ACh content of the HCl- and Fe-groups decreased transiently 24h after injection, but there was no difference in ACh content between the two groups. In the left cortex of the Fe- and HCl-groups, acetylcholinesterase (AChE) activity, which showed no difference between the two groups, decreased 30 min after injection.
These findings suggested that cortical neurons especially AChergic neurons might be irritated by a transient increase in intracranial pressure due to brain edema induced by the injection of acid into the cortex, as no specific effct of Fe3+-injection was observed in this study.抄録全体を表示PDF形式でダウンロード (676K) -
武家尾 拓司1990 年 102 巻 3-4 号 p. 465-483
発行日: 1990年
公開日: 2009/08/24
ジャーナル フリーThe effects of calmodulin inhibitors [W-7: N-(6-aminohexyl)-5-chloro-1-naphthalensulfonamide-HCl, TFP: Trifluoperazine]; cell growth inhibition, morphologic changes, and alterations of flow cytometry DNA hisotgram were studied in cultured glioma cells. The cell lines used in this experiment were KC and KY, which had been established from human glioblastomas, and C-6 from a methylnitrosourea-induced rat glioma. A dose-dependent growth inhibition was found in cells exposed to calmodulin inhibitors (W-7, TFP). The morphologic changes of cells were manifested by a rounding of the cells with numerous fine electron dense granules in the cytoplasm as early as 3 hours following exposure to calmodulin inhibitors. The influence of calmodulin inhibitors on cell kinetics was analysed by flow cytometry which revealed an accumulation of cells in G2+M phases within 24 hours after treatment. These results, together with the previous reports, indicate that the effects of calmodulin inhibitors on cell growth may be due not only to the inhibition of DNA synthesis in the G1/S boundary phase but also to the inhibition of tubulin disassembly in G2+M phases.抄録全体を表示PDF形式でダウンロード (18466K) -
鈴木 茂樹1990 年 102 巻 3-4 号 p. 485-495
発行日: 1990年
公開日: 2009/08/24
ジャーナル フリーThe contents of tyrosine (Tyr), tryptophan (Trp) and their metabolites in brain regions of ddY, non-stimulated E1 (E1 (-)) and stimulated E1 (E1 (+)) mice were measured using a Three Dimensional HPLC System.
In the cerebral cortex, striatum, midbrain and cerebellum, Trp contents of E1 (+) mice were higher than those of ddY and E1 (-) mice. The contents of 5-hydroxytryptophan in E1 (-) or (+) mice brain were lower than those in ddY mice except in the medulla oblongata. Those in the cerebral cortex, and midbrain of E1 (+) mice were lowest. Brain regional serotonin (5-HT) contents of E1 (+) mice seemed to be slightly higher than those of ddY and E1 (-) mice. In the cerebral cortex, hippocampus, medulla oblongata and cerebellum of E1 (+) or (-) mice, the kynurenin contents were remarkably high compared to ddY mice.
Although brain Tyr content did not differ between the three groups, the dopamine contents in the cerebral cortex, hypothalamus and striatum of E1 (+) mice were lower than those in ddY mice, and those in the cerebral cortex and striatum of E1 (+) mice were higher than those in E1 (-) mice. The norepinephrine contents did not differ between E1 (-) and ddY mice, but some brain regions of E1 (+) mice had higher levels. The content of 3-methoxy-4-hydroxyphenylglycol of E1 (-) mice was lower, and in E1 (+) mice was lowest in 7 brain regions. The tyramine contents in E1 (-) or (+) mice brains were higher than those in ddY mice, except in the midbrain of E1 (+) mice.
These data, suggest a possible genetic metabolic abnormality of Try and Tyr in the brains of E1 mice.抄録全体を表示PDF形式でダウンロード (6195K) -
雫 稔弘, 島田 宜浩1990 年 102 巻 3-4 号 p. 497-500
発行日: 1990年
公開日: 2009/08/24
ジャーナル フリーPDF形式でダウンロード (2124K) -
鳥羽 信行, 門原 三志男, 雫石 邦義, 広川 健, 細田 明秀, 松野 充孝, 河村 学, 渡辺 和彦, 川崎 寛中1990 年 102 巻 3-4 号 p. 501-503
発行日: 1990年
公開日: 2009/08/24
ジャーナル フリーPDF形式でダウンロード (131K) -
合原 儀行, 福本 四郎, 島田 宜浩1990 年 102 巻 3-4 号 p. 505-508
発行日: 1990年
公開日: 2009/08/24
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福本 陽平, 水町 宗治, 松田 和也, 安藤 正也, 安永 満, 小西 知己, 沖田 極1990 年 102 巻 3-4 号 p. 509-511
発行日: 1990年
公開日: 2009/08/24
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浮田 実, 西川 芳之, 松尾 龍一, 守本 洋一, 森下 博文, 臼井 裕子, 辻 孝夫1990 年 102 巻 3-4 号 p. 513-515
発行日: 1990年
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中村 利夫, 伊藤 博之, 北本 幹也, 永井 尚生, 天野 始, 小松 晃一, 田村 徹, 舛田 一成, 森石 真吾, 中山 茂, 松尾 ...1990 年 102 巻 3-4 号 p. 517-519
発行日: 1990年
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河野 宏, 真鍋 康二, 杉山 明, 川口 憲二, 尾上 公昭1990 年 102 巻 3-4 号 p. 521-523
発行日: 1990年
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発行日: 1990年
公開日: 2009/08/24
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