To compute an electrical current source from electrophysiological data, the single equivalent current dipole has been widely used. However, the method is not suitable for analyzing multiple dipoles. We used MUltiple SIgnal Classification (MUSIC) algorithm for analyzing multiple dipole sources in pain-related somatosensory evoked magnetic fields (SEFs) that had been obtained by 148-channel whole head type magnetoencephalography. Both middle latency (contralateral SI) and long latency (bilateral SII and cingulate gyri) components were clearly identified in the maps superimpksed on MR images. Not only the MUSIC results were in very good agreement with the single dipole estimation results, but also gave the temporal profiles of each current dipole source in stacks of consecutive maps. Thse results suggested that MUSIC algorithm is an effective tool for the analysis of multiple dipole sources of pain-related SEFs.
In this article, I consider whether the consent of the deceased or the bereaved family is needed or not for the anatomical dissection and preservation of the dead body from a viewpoint of medical jurisprudence and bioethics. The conclusion can be summarized as follows: The Autopsy Law 1949 is applied to the anatomical dissection and preservation of the dead body. According to this law, in principle the consent of the bereaved family is needed. However, the consent of the deceased is not needed. From a viewpoint of bioethics, especially the principle of autonomy, the consent of the deceased should be required instead of the consent of the bereaved family. To fulfill the intention of the deceased, we need to wait for new legislation or the revision of the Autopsy Law. The important things are both the recognition of the meaningful role of anatomical dissection and preservation of the dead body in medical research and education, and the consideration of the viewpoint of bioethics, especially the principle of autonomy and the derivative notion of informed consent, in case of new legislation or revision of the Autopsy Law.
A 45-year-old female was admitted to our hospital with sever abdominal fullness, and was diagnosed as polycystic liver disease with ultrasonography, abdominal CT and abdominal angiography. Almost all part of the right lobe of the liver was replaced with a lot of cysts. The liver obviously swelled up. We thought her symptom came from oppression of the digestive tract by the liver. Liver function is good. Right lobe resection, deroofing and fenestration were performed, and after operation the volume of the liver was reduced and the symptom got better. We report a case of polycystic liver disease improved with surgical therapy, adding some study with reference.