岡山医学会雑誌
Online ISSN : 1882-4528
Print ISSN : 0030-1558
75 巻, 10-12supplement 号
選択された号の論文の6件中1~6を表示しています
  • 緒方 正名, 只友 淳雄, 人見 硬, 森 忠繁, 実成 不二郎
    1963 年 75 巻 10-12supplement 号 p. 1-11
    発行日: 1964/03/05
    公開日: 2009/03/30
    ジャーナル フリー
    A survey was conducted on the prevalence of Japanese B encephalitis occurring in Okayama Prefecture from the standpoint of seasonal variation, locality, age and sex during the year 1960, and the results were compared with the national statistics. The results were as follows:
    1. The total number of patients with Japanese B encephalitis was 89, 29 deaths occured and the morbidity rate was 5.1. This 5.1 morbidity rate is of moderate prevalence for Okayama Prefecture ranking 5th place in the nation; the rate 5.1 is about 3 times the national morbidity rate.
    2. The peak period of this disease in the southern district of Okayama Prefecture comes about one week earlier than that in the northern district.
    3. The incidence of the disease during 1960 differed completely from the usual regional trend, showing a higher morbidity rate in such regions as Wake, Jodo, Oda, Katsuta Counties and Niimi City. This is in marked contrast to the usual morbidity rate which was higher in such districts as Kurashiki City, Asakuchi County and Kojima City. This seems to indicate that the prevalency of this disease is moving from the south-western to the south-eastern and north-western districts.
    4. The mortality rates of 1960 in the northern and southern districts did not change much from the years 1958 and 1959. The mortality rate in the northern district in 1960 was 60 per cent which is not an appreciable difference from 1950; however, in the southern district the mortality rate was about 42 per cent in the period of 1950-1955 and it decreased to 21.9 per cent in 1960. This decrease in the mortality rate is about one half of former years and is believed to be due to the improvement of medical facilities in the southern districts.
    5. The number of vaccinated individuals was 370, 000 and the rate of vaccination was 24.7 per cent compared to the total population. The morbidity rate in the vaccinated group was 1.9 per cent and 6.2 per cent in the unvaccinated group showing a significant decrease in the morbidity in the vaccinated group. In the x2 test of the difference between the morbidity rates of the vaccinated group and the unvaccinated group, the risk of error proved to be less than one per cent.
  • 緒方 正名, 只友 淳雄, 人見 硬, 実成 不二郎
    1963 年 75 巻 10-12supplement 号 p. 13-20
    発行日: 1964/03/05
    公開日: 2009/03/30
    ジャーナル フリー
    A survey was done on the prevalency of Japanese B encephalitis in Okayama Prefecture during the year 1961 from the standpoint of seasonal variation, age and sex as well as locality and the following results were obtained:
    1. The number of encephalitic patients was 79, the number of deaths was 29, and the mortality rate was 36.7 per cent. Its prevalency in Okayama Prefecture was intermediate, ranking eleventh in Japan with 2.1 times the national morbidity rate.
    2. As for the incidence of patients according to the season, the peak period in the southern district of Okayama Prefecture is about ten days earlier than that in the northern district.
    3. This disease increased after 1960 in Mitsu, Kibi Counties, and Takahashi City instead of such districts of Okayama City, Tamano City, Asakuchi County and Kurashiki City where it used to occur frequently. The trend during 1960 and 1961 has been to move from the former districts of the south toward the adjacent northern districts.
    4. In 1961 the mortality rate in the northern distrct was 65.4 per cent and 22.6 per cent in the southern district, showing a distinct decrease. There is an increasing morbidity in old people in the southern district. One of the reasons for the decrease in the mortality rate is due to the improvement in medical facilities since 1958.
    5. The number of persons receiving preventive vaccination in 1961 was 415, 000; the vaccination rate was 24.8 per cent. The morbidity rate was 1.4 per cent in the vaccinated group and 5.8 per cent in the unvaccinated group. The difference of the morbidity rate between the vaccinated group and the unvaccinated group is significant. The error in the statistics obtained from using the x2 test is under 0.1 per cent.
  • (I) 日本脳炎ウイルスのプラック形成について
    俵 寿太郎, 藤原 清, 内海 武夫, 前田 正利, 水原 良昌, 坂野 才藏
    1963 年 75 巻 10-12supplement 号 p. 21-23
    発行日: 1964/03/05
    公開日: 2009/03/30
    ジャーナル フリー
    A plaque assay has been developed to fill the need for a more precise virus assay. We knew something from this experiment.
    1) Washing the cell cultures with Hank's solution before inoculation of viruses was better than the washing with PBS solution to give neutral red in cells, and they will show more clear cut plaques on monolayer cultures. 2) Cultures should be used for plaque assay as soon as they grew into healthy monolayers, as young cultures are more readily maintained in good condition for 2 weeks under agar. 3) Cultures infected with JBE virus should be kept in dark place for plaque assay as soon as possible after overlay of agar to get a good observation of direct proportionality between the concentration of virus suspension and the number of PFU.
  • 稲臣 成一, 木村 道也, 板野 一男
    1963 年 75 巻 10-12supplement 号 p. 25-31
    発行日: 1964/03/05
    公開日: 2009/03/30
    ジャーナル フリー
    In 1962, mosquitoes were collected from April through October at three spots of Kurashiki city and at a single spot of Okayama city twice a week during nights by means of light-trapping.
    The mosquitoes collected were mostly Culex pipiens, Culex tritaeniorhynchus and Anopheles sinensis, and totaled 6, 718 (Kurashiki) and 6, 716 (Okayama).
    Coinciding with the findings obtained in the present decade, the incidence of Japanese B encephalitis is most dominant two to four weeks after the peak propagation of C. tritaeniorhynchus.
    While three times as many of males as females were found in C. pipiens, males were only one-seventh of females in number in C. tritaeniorhynchus, and the term of propagation is much shorter in the latter.
  • 木山 敦磨, 太田 善介, 小塚 堯, 高橋 建次, 加原 雅教
    1963 年 75 巻 10-12supplement 号 p. 33-34
    発行日: 1964/03/05
    公開日: 2009/03/30
    ジャーナル フリー
    1) Purification of JBE (Japanese B encephalitis) virus and morphological demonstration of the virus particles were tried by means of fluorocarbon treatment and elcetron microscopy
    Fluorocarbon extract of brains of mice infected with JBE virus revealed numerous spherical particles, 60 mμ in diameter by the shadowing method of electron microscopy
    Electron microscopic observation on ultrathin sections of chick red cells which were precipitated in hemagglutination induced with the fluorocarbon extract revealed round particles 30 to 40 mμ in diameter with an obscure nucleoid, on the surface of the red cells.
    These particles were believed to be JBE virus.
    2) In vivo locailzation of JBE virus antigens was persued by fluorescent antiody method in the brains of mice infected with JBE virus. The antibody was prepared from the serum of rabbits treated previously with the fluorocarbon extract.
    Specific fluorescence which was seen in granular forms was observed in nerve cells and partially in neuroglia cells of the substantia nigra and thalamus.
    3) JBE virus antigens were observed by fluorescent antibody method in phagocytes present in the cerebrospinal fluid of patients with Japanese B encephalitis. This finding was believed to contribute to early diagnosis of Japanese B encephalitis.
    4) JBE virus antigens were demonstrated by fluorescent antibody method in nerve cells and partially neuroglia cells of the brain obtained by autopsy from patients with Japanese B encephalitis.
    Specific fluorescence was seen in the Purkinje cells in the cerebellum, and granular layer of the cerebral cortex and basal ganglia, particularly substantia nigra.
  • 妹尾 左知丸, 浜田 日佐夫
    1963 年 75 巻 10-12supplement 号 p. 35
    発行日: 1964/03/05
    公開日: 2009/03/30
    ジャーナル フリー
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