Okayama Igakkai Zasshi (Journal of Okayama Medical Association)
Online ISSN : 1882-4528
Print ISSN : 0030-1558
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Volume 77, Issue 4
Displaying 1-9 of 9 articles from this issue
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  • Analytical Studies on the Column Chromatographic Determination of DNA Base Composition with Ion Exchange Resins
    HARUO OHKUMA, YASUHIRO KANEMASA
    1965 Volume 77 Issue 4 Pages 707-709
    Published: April 30, 1965
    Released on J-STAGE: August 24, 2009
    DOIhttps://doi.org/10.4044/joma1947.77.4_707
    JOURNAL FREE ACCESS
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    1. Many type of methods has been designed for determination of nucleic acid base composition. In this paper the a curacy of the results obtained using ion exchgers were tested about calf thymus DNA. The column chromatographic methods yield satisfactory results.
    2. In the course of the operation, nutralization of acidic solution of nucleic acid bases must be carried out carefully to avoid precipitation of purine bases.
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  • Corticoid Metabolism in the Body: Correlation Pattern of Blood and Urine Corticoids in Psychiatric Patients
    Mutsutoshi Kohsaka, Junzo Kobayashi, Harunori Tsuji, Kazunori Izumiya, ...
    1965 Volume 77 Issue 4 Pages 711-716
    Published: April 30, 1965
    Released on J-STAGE: August 24, 2009
    DOIhttps://doi.org/10.4044/joma1947.77.4_711
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    To investigate the corticoid metabolism In Vivo of endogenous psychosis, authors have studied the relationship between urinary and serum corticoid patterns.
    Twenty four hour urine and blood samples were taken from 17 cases of both sexes of schizophrenic patients, 17 cases from both sexes of depressed patients, 17 cases from both sexes of normal control persons, 11 cases of right and left lobotomized chronic schizophsenic patients and 12 cases from both sexes of patients with pituitary tumors, pituitary cysts, craniopharyngeomas, disturbances in hypothalamus and so on.
    The urinary 17-KS were measured by a modified method of Koch and Holtorff and 17-OHCS were measured by Silber-Porter and Bongiovanni. Bacterial β Glucuronidase was used in hydrolysis.
    The results were as follows:
    1. Free 17-OHCS in the urine and the serum were increased in schizophrenic and depressed patients in aggravating situations without exception.
    2. Urinary 17-KS were decreased in aggravating situations in both schizophrenic and depressed patients.
    3. The decrease of urinary 17-KS was significant in the male but not in the female.
    4. High serum 17-CHCS levels were followed by high urine 17-OHCS values; in other words the values moved parallel in psychotic patients.
    5. The value of conjugated 17-OHCS over free 17-OHCS (C/F) in the urine and blood always decreased in schizophrenic and depressed patients.
    6. The ratios of urinary 17-KS over free serum 17-OHCS, and urinary total 17-OHCS over free serum 17-OHCS showed significant relationships in both schizophrenic and depressed patients; these ratios are decreased in an aghravating situation.
    7. The frontal lobe plays a role in urinary 17-KS excretion. It should be emphasized that separating the frontal lobe from the thalamus or hypothalamus area will cause an increase in urinary 17-KS excretion.
    8. Urinary or serum 17-OHCS values du not move in parallel to urinary 17-KS but rather in a reverse manner in psychotic patients.
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  • Report of Field Survey on Acatalasemia and Hypocatalasemia in 1964
    Shigeo Takahara, Yoshio Ogura, Kozo Yasuhara, Hideo Okazaki, Masanori ...
    1965 Volume 77 Issue 4 Pages 717-724
    Published: April 30, 1965
    Released on J-STAGE: August 24, 2009
    DOIhttps://doi.org/10.4044/joma1947.77.4_717
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    The authors reported the results of the field survey and family follow-up of acatalasemia and hypocatalasemia during the year of 1964.
    Among 2, 964 individuals submitted to the screening test for the purpose of detecting acatalasemic gene carriers in various parts of Japan, two proved to be hypocatalasemia.
    On examination of the remaining 34 members of two acatalasemic families, there were one case of acatalasemia and 11 of hypocatalasemia in addition to the formerly known cases.
    Consequently, the total of reported acatalasemic cases amounted to 80 cases of 37 families by the end of 1964.
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  • Chromosome Studies On Human Leukemias
    Norio Kawamura
    1965 Volume 77 Issue 4 Pages 725-742
    Published: April 30, 1965
    Released on J-STAGE: August 24, 2009
    DOIhttps://doi.org/10.4044/joma1947.77.4_725
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    Chromosome studies were carried out on 13 cases of various types of leukemias (acute myelogenous and lymphocytic leukemias, monocytic leukemia, erythroleukemia, chronic myelogenous and lymphocytic leukemias, and the Down's syndrome associated with acute lymphocytic leukemia) and on 5 cases of normal controls.
    In 6 out of the 13 cases, both peripheral blood and bone marrow were studied, and in the other 7 cases only peripheral blood was used.
    The Ph1 chromosomes and a rather low diploid modality were observed in either of 2 cases of chronic myelogenous leukemis. No chromosome abnormality except for the trisomy of the 21st chromosome (Denver classification) was observed in a case of the Down's syndrome associated with acute lymphocytic leukemia. In the other types of leukemias, no significant chromosome abnormality was found either in peripheral blood or bone marrow specimens.
    These findings suggest that in human leukemias there is no consistent chromosome change except for the Ph1 chromosome in chronic myelogenous leukemia.
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  • Physiological Aspects of Filamentous Elongated Bacteria Induced by X-ray Irradiation
    Satoru Nishii
    1965 Volume 77 Issue 4 Pages 743-749
    Published: April 30, 1965
    Released on J-STAGE: August 24, 2009
    DOIhttps://doi.org/10.4044/joma1947.77.4_743
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    Sequences of cytological changes occurring in some bacteria following irradiation of X-ray have been described by many workers. It is known that, unless bacteria receive a considerable amount of irradiation, they continue to grow and become elongated, only their cell division being inhibited.
    In the present study, the author gave physiological aspects on the filamentous Salmonella typhi H901W elongated by culture following after X-ray irradiation (2000 r).
    1. It was observed by Warburg's manometric technique that most of enzyme activities in the elongated cells were reduced. Especially, the induction of a adaptive enzyme for glucuronic acid could not be observed in the elongated cells.
    2. In the post culture following after X-ray irradiation, protein and RNA increased as long as cell body elongates but DNA didn't increase. This result coincides with the finding that irradiated Salmonella typhi elongated without the increasing of number of nuclear apparatus.
    3. In the studies on the agglutination reaction of the elongated cells, the author found that the agglutinability with antibody were reduced and moreover the isoelectric point moved slightly against to neutral pH.
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  • Studies on Clonorchis sinensis
    Part 1 Geographical distribution in Okayama Prefecture
    Yosihiro Ito, Daigoro Sakumoto, Kazuo Itano, Taneo Tsubota, Seiiti Ina ...
    1965 Volume 77 Issue 4 Pages 751-757
    Published: April 30, 1965
    Released on J-STAGE: August 24, 2009
    DOIhttps://doi.org/10.4044/joma1947.77.4_751
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    Okayama Prefecture has been known as one of endemic areas of Clonorchis sinensis in Japan. In on attempt to see the chronological change in the area, several investigations have been condncted on the distribution of the parasite.
    1. Parafossalurus manchouricus, the first intermediate host, was found in three cities and in two other districts, and the area of endemicity is seemingly less extensive than that reported by Nagano (1954).
    2. The metacercarial stages were recognized in three cities and in a county being coextensive with the distribution of the snails.
    3. The eggs in feces were recovered in both previous and present regions infested with the snails.
    4. The avarage infection rate of liver flukes in the areas examined was approximately two per cent with an exception of seven per cent in Saidaiji City.
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  • [title in Japanese]
    1965 Volume 77 Issue 4 Pages 759-762
    Published: April 30, 1965
    Released on J-STAGE: August 24, 2009
    DOIhttps://doi.org/10.4044/joma1947.77.4_759
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  • [title in Japanese]
    1965 Volume 77 Issue 4 Pages 762-767
    Published: April 30, 1965
    Released on J-STAGE: August 24, 2009
    DOIhttps://doi.org/10.4044/joma1947.77.4_762
    JOURNAL FREE ACCESS
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  • [title in Japanese]
    1965 Volume 77 Issue 4 Pages 767-772
    Published: April 30, 1965
    Released on J-STAGE: August 24, 2009
    DOIhttps://doi.org/10.4044/joma1947.77.4_767
    JOURNAL FREE ACCESS
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