In 1900, C.S. TOMES  in his observations on the fish teeth stated that in fish teeth the dentin is exposed from the enamel cap to the supporting bone and although it seems to be an easy task whether the dentin is covered with a thin layer of enamel or not, it is actually a very difficult one (Fig. 1). This dentin is called “Kragen” by SCHMIDT and KEIL  and “outer dentin” by ISOKAWA , one of the present authors. The surface of this dentin is given by TOMES to be brittle and become dissolved by the presence of an acid. On the other hand, CARTER  stated that in the teeth of hake the surface of outer dentin lacks any indication of enamel. The authors concerned themselves with historadiographic observations of certain fish teeth of this outer dentin in certain fish teeth so as to contribute toward an elucidation of the long-standing problem.
Carcinoma of the tongue, the most malignant type of cancers, is known to occur more frequently in males than in females. For descriptive purposes, carcinoma of the tongue is treated either as carcinoma on the base of the tongue or as carcinoma of the tongue excluding the basal region. Of the latter type, carcinoma of the tongue is most commonly found on the side of the tongue and one on the tip or dorsum is relatively rare. Carcinoma on the base of the tongue, on the other hand, is comparatively restricted in its incidence among the Japanese, accounting for nearly 20 % in the total occurrence of carcinoma of the tongue. In Europe, its incidence is much higher and anywhere 1/4 to 2/5 of carcinoma of the tongue is said to be of the basal type. By way of histologic types, a greater portion of carcinoma on the base of the tongue is of the squamous-cell carcinoma and, in many cases, they are relatively undifferentiated. Although there are other types such as lymphoepithelioma and transitional-cell carcinoma, adenocarcinoma is only rarely found. The present report describes a case of adenocarcinoma recently encountered by the Department of Pathology, Nihon University School of Dentistry, Tokyo, Japan.
In our previous report , we established the fact that a conjoint administration.of vitamin C and glucose-cysteine is quite potent as an antidotal agent against acetaldehyde and nicotine. In the present paper, we are concerned with carbon tetrachloridum and chloro-form using the same antidotal agent. Since the former is known as a unique substance associated with the liver disturbance and the latter with various forms of the cardiac complaints, our understanding relative to the antidotal action of vitamin C on these drugs would also contribute to better elucidation of the pharmacological mechanisms of the liver and heart.