Staphylococci pyogenes and streptococci pyogenes are generally acknowledged to be pathogenic bacteria in connection with acute suppurative diseases. However, their bacteriological study in the oral area has been scanty so far and the necessity for detection of these bacteria is made all the more imperative by the recent appearance of so-called antibiotics-fast bacteria. Therefore, the authors have undertaken the following series of experiment on the subject. The sensibility test has also been done on separated bacteria as an aid for bacteriological therapy.

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In the present experiment efforts have been made by the authors to determine possible influence which the occlusion movement exercises on the secretion of parotid saliva in the Japanese.
The following findings are obtained as a result of a series of tests described in the foregoing sections:
1) No increase in the salivary secretion has been observed in the case of the empty occlusion movement where nothing is inserted in the mouth as contrasted against the salivary secretion under normal circumstances. On the contrary, a decrease is observed in some cases. It may be attributed to the fact that when the empty occlusion movement is repeated for a certain length of time, it does not bring about any reflex secretion but rather works as inhibitory factor upon the normal secretion.
2) Although paraffin wax is accompanied with a certain unpleasant taste, it evidently stimulates the secretion of reflex saliva. The amount of parotid saliva that was induced as a consequence is about 7.5 times as much as the case of normal secretion.
3) When a piece of chewing-gum is inserted in the mouth for a length of time, there is seen a far greater increase in the salivary secretion than the case of 2) above. The average increase amounts to 45.2 times as much as the normal secretion. This phenomenon more or less parallels to a set of findings which were obtained by the present authors (SUHARA and ASAKAWA) as a result of tests in which lunch and other foods were provided to the examinees.
4) Insertion of a tasteless chewing-gum also increases the salivary secretion by about 6.9 times on the average. Infusion of acetic vinyl in the mouth is known to give rise to a similar increase.
The conclusion to be drawn from these series of tests indicates the insertion of various substances in the oral cavity and the occlusion movement thereof brings about an increase in the salivary secretion, whereas the mere occlusion movement without anything in the oral cavity is not accompanied by an increase worthy of note.

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The following is the overall result obtained as a consequence of a comparison as regrads various sympathetic stimulants tested on the jejunums of domestic rabbits. Three sets of ratings as strong, medium and weak are used to indicate the quantity required to bring forth the prescribed function in the 40 mol Jyrode solution. The test drugs are g iven in the order of their effects.

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Intrarod structures in enamel lamella from human beings and cows were examined with the electron microscope. The microscope revealed the following:
1. The lamella's intrarod structures are composed of (1) intrarod organic substance and (2) intrarod needle-form fine crystals.
2. A lamella's intrarod structure, however, is often composed only of intrarod organic substance.
3. The intrarod organic substance probably contains calcium salts of a noncrystalline nature. The intrarod crystals probably have a twin-crystal character.
4. The intrarod crystals are seen patterned mosaically in the intrarod organic substance.
5. These crystals are seen running in every direction, however most run parallel.
6. The proportion of intrarod organic substance and intrarod crystals is a remarkable histologic difference between rods contained in normal enamel and lamellae. The lamella's rods contain proportionately more intrarod organic substance. In fact sometimes no crystals at all are seen in the lamella's rods.

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