The concentration of platelet becomes maximum near the vessel wall in the blood flow, and this is referred to as the “Near Wall Excess, NEW.” This excessive concentration of platelet near the wall plays a major role for the hemostasis process, and this concentration occurs by the repetitive interaction with red blood cells. In order to make the clinical application of artificial platelet successful, we need to know the microscopic motion of platelet or its substitute in the blood flow and to explore the way how to achieve the NWE of platelet. In this review, we will have a literature survey of the previous studies on the microscopic motion of platelet.
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